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Pepperdine University

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Angiogenesis Lymphangiogenesis Cell Survival

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Comparison Of Downstream Cell Survival Responses In Huvecs And Hlecs During Vegf Signaling, Haley Smith Apr 2015

Comparison Of Downstream Cell Survival Responses In Huvecs And Hlecs During Vegf Signaling, Haley Smith

Seaver College Research And Scholarly Achievement Symposium

Comparison of Downstream Cell Survival Responses in HUVECs and HLECs During VEGF Signaling

Author: Haley M. Smith

Mentor: Thomas L. Vandergon

Angiogenesis and lymphangiogenesis are vital processes that allow the formation of new blood and lymph vessels from existing blood or lymph vessels. Formation of these vessels is essential to bring oxygen and nutrients to the body as well as maintaining tissue fluid balance. New blood or lymph vessel growth occurs in response to Vascular Endothelial Growth Factor (VEGF) signaling to vascular endothelial cells. The VEGF signal molecules bind to cell surface receptors and elicit a variety of responses including …