Medicine and Health Sciences Commons^™

Improving Oral Health In Pakistan Using Dental Hygienists, Musarrat Anjum Shah

Dental Hygiene Master's Papers and Projects

This document presents a review of the literature addressing education, healthcare, healthcare delivery and finance in Pakistan and the oral health status of the Pakistani people. Considering the enormous unmet oral health needs, the insufficient supply of dental professionals and the current unstructured dental hygiene curriculum in Pakistan, this document offers a mission, vision, and goals for the new dental hygiene theoretical framework for Pakistan. Moreover, it offers recommendations for competency-based dental hygiene education and practice, professional licensing, a practice act, and a dental hygiene scope of practice to help protect the welfare of the Pakistani public, i.e., increasing the …

In Vivo Murine Melanoma Tumor Responses To Nanosecond Pulsed Electric Field Treatment, Xinhua Chen

Theses and Dissertations in Biomedical Sciences

High intensity nanosecond pulsed electric fields (nsPEF) were applied to melanoma tumors to observe functional and structural biological changes and to investigate the possible molecular mechanisms responsible. An animal model was set up by injecting B16F10 mouse melanoma cells into SKH-1 mice. A treatment (Tx) of 100 pulses: 300 nanosecond duration; 40 kV/cm field strength; at 0.5 Hz rate were delivered to melanoma tumors in 120 mice. The nsPEF Txcaused tumor self-destruction with sharply decreased cell volumes and shrunken nuclei. The apoptotic biochemical tests confirmed nsPEF Tx induced apoptosis in a time-dependent manner. Examination of gross vessel and micro-vessel density …

Nanosecond Pulsed Electric Fields Induce A Mitochondria-Independent Apoptosis In B16f10 Melanoma Cells In Vitro, Wentia Elissa Ford

Theses and Dissertations in Biomedical Sciences

Nanosecond pulsed electric fields (nsPEFs) are ultra-short pulses that induce direct electric field and biological effects that initiate apoptosis. Here the application of ten 300ns pulses ranging in electric fields from 12kV/cm-60kV/cm was administered to determine the effects on B16F10 melanoma cells evaluated by in vitro studies. Initial application of nsPEFs demonstrated apoptosis induction in an electric field- and pulse number-dependent manner measured by caspase activation that correlated with decrease in cell viability 24hr post pulse. In addition caspase activity was shown to be independent of calcium mobilization though ions may play a part in other aspects of apoptosis. The …

Effect Of Outside Employment On Academic Success Among Full-Time Associate Degree Nursing Students, Julian A. Moore

Educational Leadership & Workforce Development Theses & Dissertations

Large portions of the United States are experiencing a shortage of nurses in the workplace. In 2001 the American Hospital Association reported that there were 126,000 vacancies for RNs nationwide. Sixty percent of all U.S. educated RNs who entered the field in 2000 received their education at the associate degree level and 79% of these associate degree recipients graduated from a community college. Improving completion rates in nursing programs is one major strategy in the effort to relieve this shortage of nurses.

The intent of this research was to study the effect of various factors on the academic achievement of …

Identifying Determinants Of Physical Activity In Maritime Union Members Using The Theory Of Planned Behavior, Susan Atkinson Tweed

Health Services Research Dissertations

This study examined the usefulness of the Theory of Planned Behavior to predict how attitude, subjective norm, perceived behavioral control, and intention are associated with physical activity in longshoremen from the Hampton Roads Shipping Association-International Longshoreman's Association (HRSA-ILA). The study was conducted in two phases. In the first phase, five focus groups were conducted to elicit information about the health behaviors of longshoremen. From the results of these focus groups, a 90-question, theory based, self-reported questionnaire was developed to identify beliefs, attitudes, subjective norms, perceived behavioral control, and intentions that contribute to longshoremen engaging in physical activity. In the second …

Bisphenol A Blood And Saliva Levels Prior To And After Dental Sealant Placement In Adults, Joyce Marie Downs

Dental Hygiene Theses & Dissertations

Placement of pit and fissure dental sealants is an effective therapy for tooth decay prevention and is widely accepted as a standard of care throughout the United States. Pit and fissure dental sealants (sealants) are manufactured using the resin component of composite dental materials, formed by reacting glycidyl methacrylate with bisphenol A. Bisphenol A (BPA) is a hormonally active, synthetic chemical that is part of a broad group of chemicals known as endocrine disrupting compounds, xenoestrogens, which mimic bioactivity of estrogen. This study measured BP A in saliva and blood after the placement of a widely used, pit and fissure …

In Vitro Comparison Of 360° Unirotational Disposable Prophylaxis Angles Versus 90° Reciprocating Disposable Prophylaxis Angles On Spatter During Rubber Cup Polishing, Kelly Marie Schulz

Dental Hygiene Theses & Dissertations

The purpose of this in vitro study was to compare the traditional 360° unirotational disposable prophylaxis angle (DPA) to a 90° reciprocating DPA in terms of spatter production. The 2x3x3 factorial design involved: 2 types of DP As x 3 types of prophylaxis pastes (fine, medium and coarse) x 3 dental handpiece revolutions per minute (rpm) settings (1500, 2000, and 3000). The eStylus'™ operated the DP As under controlled speeds. Using a mounted dental manikin, 90° reciprocating DP As and 360° unirotational DP As were evaluated for spatter production with the use of prophylaxis pastes of various grits in 270 …

College Students Concern Toward Public Intoxication, Ashley N. Mason

Sociology & Criminal Justice Theses & Dissertations

A survey of college students was administered in order to better understand why students choose to either walk after consuming alcoholic beverages or drive after consuming alcoholic beverages. Students were asked to answer demographic questions along with opinion questions as well. The main variables used in this study were perceived severity of offense, perceived certainty of offense (i.e. level of concern about getting stopped), moral condemnation and punishment avoidance.

Univariate, bivariate and multivariate analyses were examined to see what characteristics have an impact on students behavior regarding public intoxication. Although significant with one or both dependent variables, perceived severity, perceived …

An Assessment Of An Education Intervention On Youth Sports Coaches Knowledge Of Concussions, Heidi Elizabeth Brigham

Human Movement Sciences & Special Education Theses & Dissertations

Research has shown that sport related concussions are occurring at high rates across the United States. Research has also shown that there are many misconceptions among youth sports coaches regarding concussions. Therefore the purpose of this study was to determine the effects of an educational intervention on the knowledge of concussion recognition, management and prevention for youth sports coaches. A secondary purpose was to compare various relationships between demographic characteristics and the concussion knowledge assessment scores. A twenty-one question multiple choice assessment and 16 option symptom recognition checklist was utilized to assess concussion knowledge prior to and following an educational …

Real-Time Ultrasound Simulation For Medical Training And Standardized Patient Assessment, Bo Sun

Computational Modeling & Simulation Engineering Theses & Dissertations

With the increasing role played by ultrasound in clinical diagnostics, ultrasound training in medical education has become more and more important. The clinical routine for ultrasound training is on real patients; therefore monitored and guided examinations involving medical students are quite time-constrained. Furthermore, standardized patients (SPs), who are increasingly used in medical school for teaching and assessing medical students, need to be augmented. These SPs are typically healthy individuals who can not accurately portray the variety of abnormalities that are needed for training especially when medical examinations involve instrument interactions. To augment SPs in a realistically effective way and also …

The Application Of Innovative High-Throughput Techniques To Serum Biomarker Discovery, Izabela Debkiewicz Karbassi

Theses and Dissertations in Biomedical Sciences

Time-of-flight mass spectrometry continues to evolve as a promising technique for serum protein expression profiling and biomarker discovery. As seen in our initial SELDI-TOF MS and MALDI-TOF MS profiling study of serum for the assessment of breast cancer risk, many profiling strategies typically employ single chemical affinity beads or surfaces to decrease sample complexity of dynamic fluids like serum. However, most proteins, captured on a particular surface or bead, are not resolved in the lower mass range where mass spectrometers are most effective. To this end we have designed an expression profiling workflow that utilizes immobilized trypsin paramagnetic beads in …

Cannabinoids: A Novel Treatment Strategy For Retinal Neurodegenerative Disorders, Sandeep Samudre

Theses and Dissertations in Biomedical Sciences

Synthetic and naturally occurring cannabinoids are known to decrease intraocular pressure (IOP). Glaucomatous damage to the retina and optic nerve progresses even after therapy to maintain normal intraocular pressure (IOP). Topical application of cannabinoids decreases IOP while not affecting blood pressure or heart rate. Based upon their effects on other tissues, we hypothesize that these analogs reduce IOP and may also confer direct neuroprotective effects on the retina, possibly via CB1 and/or CB2 receptors. The purpose of this study is to determine if the newly synthesized CB agonists, lipid soluble O-1812 (CB 1), and water soluble O-2545 (CB 1

The …

Application Of The Interactional Model Of Cultural Diversity To Identify Diversity Climate Factors Associated With Organizational Effectiveness In Accredited U.S. Physical Therapist Education Programs, Elizabeth Francis Giles

Health Services Research Dissertations

Accredited U.S. physical therapist education programs are responsible for the preparation of its graduates to provide culturally sensitive care to meet the physical therapy needs of an increasingly diverse population. While the importance of workforce diversity has been articulated, the effect of diversity climate on organizational effectiveness within accredited U.S. physical therapist education programs has not been described. The purpose of this study was to evaluate the effectiveness of the Interactional Model of Cultural Diversity (IMCD, Cox, 1993) as a theoretical framework to identify diversity climate factors associated with organizational effectiveness in accredited U.S. physical therapist education programs. A descriptive, …

Modeling Physical Activity In Working Adults: How Suitable Is The Expanded Parallel Process Model?, Adwoa B-H-Sam

Health Services Research Dissertations

This study is an assessment of the usefulness of the Expanded Parallel Process Model in predicting health enhancing physical activity as an outcome variable. The theory is tested in the context of risk for coronary heart disease and involves secondary analyses of a dataset from a group of working adults. These individuals had elected first to participate in a health plan ‘Quality Improvement Study’ and were then randomly selected to receive an intervention program designed to get people to be more active.

Data on self-reported demographics, physical activity levels, health status characteristics and perceptions measured on a Likert-type scale known …

Gene Therapy Using Tet-Repressor System To Modulate Prostate Tumor Microenvironment, Nazita Yousefieh

Theses and Dissertations in Biomedical Sciences

Prostate cancer is the most commonly diagnosed malignancy in men in the United States and is projected to be the third most frequent cause of male cancer-related deaths in 2007 after lung and skin cancers. The initial treatment for prostate cancer at early stages is prostatectomy or radiation, which usually is curative. However, approximately 20% of patients are not cured by such treatments and their cancer recurs, sometimes with long latencies. In other patients prostate cancer is diagnosed only after the cancer has metastasized and there are no effective therapies at this stage. Therefore immunotherapy seems to be a promising …

Maldi Mass Spectrometry Imaging For The Discovery Of Prostate Carcinoma Biomarkers, Lisa Harris Cazares

Theses and Dissertations in Biomedical Sciences

The elucidation of new biological markers of prostate cancer (PCa) should aid in the detection, and prognosis of this disease. Diagnostic decision making by pathologists in prostate cancer is highly dependent on tissue morphology. The ability to localize disease-specific molecular changes in tissue would help improve this critical pathology decision making process. Direct profiling of proteins in tissue sections using MALDI imaging mass spectrometry (MALDI-IMS) has the power to link molecular detail to morphological and pathological changes, enhancing the ability to identify candidates for new specific biomarkers. However, critical questions remain regarding the integration of this technique with clinical decision …