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Full-Text Articles in Medicine and Health Sciences
3d-Printed Membrane For Guided Tissue Regeneration, Lobat Tayebi, Morteza Rasoulianboroujeni, Keyvan Moharamzadeh, Thafar K.D. Almela, Zhanfeng Cui, Hua Ye
3d-Printed Membrane For Guided Tissue Regeneration, Lobat Tayebi, Morteza Rasoulianboroujeni, Keyvan Moharamzadeh, Thafar K.D. Almela, Zhanfeng Cui, Hua Ye
School of Dentistry Faculty Research and Publications
Three-dimensional (3D) printing is currently being intensely studied for a diverse set of applications, including the development of bioengineered tissues, as well as the production of functional biomedical materials and devices for dental and orthopedic applications. The aim of this study was to develop and characterize a 3D-printed hybrid construct that can be potentially suitable for guided tissue regeneration (GTR). For this purpose, the rheologyanalyses have been performed on different bioinks and a specific solution comprising 8% gelatin, 2% elastin and 0.5% sodium hyaluronate has been selected as the most suitable composition for printing a structured membrane for GTR …
Collagenous Matrix Supported By A 3d-Printed Scaffold For Osteogenic Differentiation Of Dental Pulp Cells, Farahnaz Fahimipour, Erfan Dashtimoghadam, Morteza Rasoulianboroujeni, Mostafa Yazdimamaghani, Kimia Khoshroo, Mohammadreza Tahriri, Amir Yadegari, Jose Gonzalez, Daryoosh Vashaee, Douglas C. Lobner, Tahereh S. Jafarzadeh Kashi, Lobat Tayebi
Collagenous Matrix Supported By A 3d-Printed Scaffold For Osteogenic Differentiation Of Dental Pulp Cells, Farahnaz Fahimipour, Erfan Dashtimoghadam, Morteza Rasoulianboroujeni, Mostafa Yazdimamaghani, Kimia Khoshroo, Mohammadreza Tahriri, Amir Yadegari, Jose Gonzalez, Daryoosh Vashaee, Douglas C. Lobner, Tahereh S. Jafarzadeh Kashi, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Objective
A systematic characterization of hybrid scaffolds, fabricated based on combinatorial additive manufacturing technique and freeze-drying method, is presented as a new platform for osteoblastic differentiation of dental pulp cells (DPCs).
Methods
The scaffolds were consisted of a collagenous matrix embedded in a 3D-printed beta-tricalcium phosphate (β-TCP) as the mineral phase. The developed construct design was intended to achieve mechanical robustness owing to 3D-printed β-TCP scaffold, and biologically active 3D cell culture matrix pertaining to the Collagen extracellular matrix. The β-TCP precursor formulations were investigated for their flow-ability at various temperatures, which optimized for fabrication of 3D printed scaffolds with …