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Full-Text Articles in Medicine and Health Sciences

Quantifying Fluid Shear Stress In A Rocking Culture Dish, Xiaozhou Zhou, Dawei Liu, Lidan You, Liyun Wang May 2010

Quantifying Fluid Shear Stress In A Rocking Culture Dish, Xiaozhou Zhou, Dawei Liu, Lidan You, Liyun Wang

School of Dentistry Faculty Research and Publications

Fluid shear stress (FSS) is an important stimulus for cell functions. Compared with the well established parallel-plate and cone-and-plate systems, a rocking “see-saw” system offers some advantages such as easy operation, low cost, and high throughput. However, the FSS spatiotemporal pattern in the system has not been quantified. In the present study, we developed a lubrication-based model to analyze the FSS distributions in a rocking rectangular culture dish. We identified an important parameter (the critical flip angle) that dictates the overall FSS behaviors and suggested the right conditions to achieving temporally oscillating and spatially relatively uniform FSS. If the maximal …


Cementoblastic Response To High Vs. Low Level Of Mechanical Force In Vitro, Natalie Nicole Mullally Apr 2010

Cementoblastic Response To High Vs. Low Level Of Mechanical Force In Vitro, Natalie Nicole Mullally

Master's Theses (2009 -)

One of the possible complications of orthodontic treatment is apical root resorption. During orthodontic treatment, as the teeth are being moved, the alveolar bone is continually being modeled to accommodate the teeth. This process activates specific cells that are responsible for bone resorption and can have the unwanted effect of resorbing the apex of the tooth root adjacent to the bone. It is unclear exactly what aspects of orthodontic treatment may trigger the resorptive process. A positive correlation, however, between root resorption and mechanical loading applied during orthodontic tooth movement has been established implicating orthodontic treatment in this adverse effect. …