Medicine and Health Sciences Commons^™

Pilot Evaluation Of A New Urine Progesterone Test To Confirm Ovulation In Women Using A Fertility Monitor, Thomas Bouchard, Richard Fehring, Mary Schneider

College of Nursing Faculty Research and Publications

Background

Progesterone rises ~24–36 h after ovulation. Past studies using ultrasound-confirmed ovulation have shown that three consecutive tests with a threshold of 5μg/mL of urine progesterone (pregnanediol-3-glucuronide, PDG), taken after the luteinizing hormone (LH) surge, confirmed ovulation with 100% specificity.

Purpose

The purpose of this study was to a evaluate a new urine PDG self-test to retrospectively confirm ovulation in women who were monitoring ovulation using a hormonal fertility monitor.

Methods

Thirteen women of reproductive age were recruited to test urine PDG while using their home hormonal fertility monitor. The monitor measured the rise in estrogen (estrone-3-glucuronide, E3G) and LH …

Use Of Urinary Pregnanediol 3-Glucuronide To Confirm Ovulation, R. Ecochard, R. Leiva, Thomas Bouchard, H. Boehringer, A. Direito, A. Mariani, Richard Fehring

College of Nursing Faculty Research and Publications

Objective

Urinary hormonal markers may assist in increasing the efficacy of Fertility Awareness Based Methods (FABM). This study uses urinary pregnanediol-3a-glucuronide (PDG) testing to more accurately identify the infertile phase of the menstrual cycle in the setting of FABM.

Methods

Secondary analysis of an observational and simulation study, multicentre, European study. The study includes 107 women and tracks daily first morning urine (FMU), observed the changes in cervical mucus discharge, and ultrasonography to identify the day of ovulation over 326 menstrual cycles. The following three scenarios were tested: (A) use of the daily pregnandiol-3a-glucuronide (PDG) test alone; (B) use of …

Accuracy Of The Peak Day Of Cervical Mucus As A Biological Marker Of Fertility, Richard Fehring

College of Nursing Faculty Research and Publications

The (PD) peak day of cervical mucus is an important biologic marker for the self-determination of the optimal time of fertility in a woman’s menstrual cycle. The purpose of this article is to provide evidence (literature and empiric) for the accuracy of the PD of cervical mucus as a biologic marker of peak fertility and the estimated day of ovulation. An analysis of data from four published studies that compared the self-determination of the PD of cervical mucus with the urinary luteinizing hormone (LH) surge was conducted. The four studies yielded 108 menstrual cycle charts from 53 women participants. The …

Evaluation Of The Lady Free Biotester® In Determining The Fertile Period, Richard Fehring, Nancy Gaska

College of Nursing Faculty Research and Publications

Small hand-held microscopes have been developed for self-observation of salivary ferning patterns to detect the fertile time of a woman’s menstrual cycle. The purpose of this study was to evaluate one such microscope, the Lady Free Biotester^®, by comparing it with the self-observation of cervical-vaginal mucus and with the self-detection of luteinizing hormone (LH) in the urine. Twelve natural family planning teachers (average age 34.6 years) observed their cervical-vaginal mucus, tested their urine for LH, and observed salivary and cervical-vaginal mucus ferning patterns (with the Lady Free Biotester) for two menstrual cycles. Data indicated that there was a …