Medicine and Health Sciences Commons^™

Transdermal Delivery Of Functional Collagen Via Polyvinylpyrrolidone Microneedles, Wenchao Sun, Mohammed Inayathullah, Martin A. C. Manoukian, Andrey V. Malkovskiy, Sathish Manickam, M. Peter Marinkovich, Alfred T. Lane, Lobat Tayebi, Alexander M. Seifalian, Jayakumar Rajadas

School of Dentistry Faculty Research and Publications

Collagen makes up a large proportion of the human body, particularly the skin. As the body ages, collagen content decreases, resulting in wrinkled skin and decreased wound healing capabilities. This paper presents a method of delivering type I collagen into porcine and human skin utilizing a polyvinylpyrrolidone microneedle delivery system. The microneedle patches were made with concentrations of 1, 2, 4, and 8% type I collagen (w/w). Microneedle structures and the distribution of collagen were characterized using scanning electron microscopy and confocal microscopy. Patches were then applied on the porcine and human skin, and their effectiveness was examined using fluorescence …

Biomaterial Properties Of Titanium In Dentistry, Soni Prasad, Mark Ehrensberger, Monica Prasad Gibson, Hyeongil Kim, Edward A. Monaco, Jr.

School of Dentistry Faculty Research and Publications

Background

Among various dental materials and their successful restorative uses, titanium provides an excellent example of integrating science and technology involving multiple disciplines of dentistry including biomaterials, prosthodontics and surgical sciences. Titanium and its alloys have emerged as a material of choice for dental implants fulfilling all requirements biologically, chemically and mechanically. Several excellent reviews have discussed the properties of titanium and its surface characteristics that render it biocompatible. However, in most patients, titanium implants are used alongside several other metals. Presence of different metals in the same oral environment can alter the properties of titanium. Other influencing factors include …

Condylar Hyperplasia: An Updated Review Of The Literature, Luis Eduardo Almeida, Joseph Zacharias, Sean Pierce

School of Dentistry Faculty Research and Publications

Condylar hyperplasia (CH) is a rare disorder characterized by excessive bone growth that almost always presents unilaterally, resulting in facial asymmetry. Classification of the different types of CH can differ depending on the authors. Correct diagnosis is critical in determining the proper treatments and timing. This paper is a review of the recent literature on the epidemiology, etiology, diagnosis, classification, and surgical treatments of CH.

Imaging Of The Jaws, Lisa J. Koenig

School of Dentistry Faculty Research and Publications

No abstract provided.

Children’S Oral Health Assessment, Prevention, And Treatment, Christopher Okunseri, Cesar Gonzalez, Brian D. Hodgson

School of Dentistry Faculty Research and Publications

No abstract provided.

Social Media In The Dental School Environment, Part A: Benefits, Challenges, And Recommendations For Use, Heiko Spallek, Sharon P. Turner, Evelyn Donate-Bartfield, David Chambers, Maureen Mcandrew, Pamela Zarkowski, Nadeem Karimbux

School of Dentistry Faculty Research and Publications

Social media consist of powerful tools that impact not only communication but relationships among people, thus posing an inherent challenge to the traditional standards of who we are as dental educators and what we can expect of each other. This article examines how the world of social media has changed dental education. Its goal is to outline the complex issues that social media use presents for academic dental institutions and to examine these issues from personal, professional, and legal perspectives. After providing an update on social media, the article considers the advantages and risks associated with the use of social …

Social Media In The Dental School Environment, Part B: Curricular Considerations, Heiko Spallek, Sharon P. Turner, Evelyn Donate-Bartfield, David Chambers, Maureen Mcandrew, Pamela Zarkowski, Nadeem Karimbux

School of Dentistry Faculty Research and Publications

The goal of this article is to describe the broad curricular constructs surrounding teaching and learning about social media in dental education. This analysis takes into account timing, development, and assessment of the knowledge, skills, attitudes, and behaviors needed to effectively use social media tools as a contemporary dentist. Three developmental stages in a student’s path to becoming a competent professional are described: from undergraduate to dental student, from the classroom and preclinical simulation laboratory to the clinical setting, and from dental student to licensed practitioner. Considerations for developing the dental curriculum and suggestions for effective instruction at each stage …

Dental Service Utilization And Neighborhood Characteristics In Young Adults In The United States: A Multilevel Approach, Christopher Okunseri, Raul I. Garcia, Elaye Okunseri, Alexis D. Visotcky, Aniko Szabo

School of Dentistry Faculty Research and Publications

Objective: To investigate the association between neighborhood level factors and dental visits in young adults in the United States after adjusting for individual level factors.

Methods: The National Longitudinal Study of Adolescent Health Wave 1 (1994-1995) to Wave III (2001-2002) was analyzed. The primary outcome of having had at least one dental visit in the previous 12 months was analyzed via a multilevel random-effects logistic model accounting for geographic clustering in Wave III and survey design clustering from Wave I. Neighborhood level covariates were defined at the census tract level.

Results: Overall rate of dental visits was 57 percent, highest …

Labial Reduction Guide For Laminate Veneer Preparation, Seok-Hwan Cho, William W. Nagy

School of Dentistry Faculty Research and Publications

This article describes a method of fabricating a labial reduction guide for laminate veneer preparations by using a digital tire tread depth gauge and orthodontic wire. The labial reduction guide can help clinicians to achieve accurate reduction of the labial surface. Minimally invasive porcelain laminate veneers have become a popular option in esthetic dentistry. Porcelain laminate veneers require only 25% to 50% of the amount of tooth reduction required for complete coverage restorations.Nevertheless, adequate labial reduction is important in creating optimal esthetics. However, excessive reduction can lead to compromised bond strength due to penetration of the enamel surface. Typically, the …

The Relationship Between Consumption Of Beverages And Tooth Wear Among Adults In The United States, Christopher Okunseri, May C.M. Wong, David T.W. Yau, Colman Mcgrath, Aniko Szabo

School of Dentistry Faculty Research and Publications

Objectives: To investigate the prevalence and severity of tooth wear (TW) and its relationship with consumption of beverages among adults in the United States.

Methods: The National Health and Nutrition Examinations Survey data for 2003-2004 was analyzed. TW was defined as “wear on at least one surface of at least one examined tooth.” Drink/juice consumption was ascertained via a Food Frequency Questionnaire processed with Diet*Calc software to obtain the average daily consumption frequency for all queried drinks and juice categories including milk. Survey-weighted descriptive and multivariable analyses with interaction terms were performed.

Results: Our study sample consisted of 3,773 adults …

Platform Switching Of Implants May Decrease Bone Loss, Gary L. Stafford

School of Dentistry Faculty Research and Publications

Data sources: PubMed/Medline, Web of Science and the Cochrane Oral Health Group Trials Register, clinicaltrials.gov, www.centerwatch.com/clinical-trials, www.clinicalconnection.com supplemented by a manual search of dental implants-related journals.

Study selection: Clinical studies, either randomised or not, comparing implant failure rates, marginal bone level (MBL) and/or postoperative infection in any group of patients receiving platform-switched implants or platform-matched implants were considered.

Data extraction and synthesis: Study quality was assessed using the Newcastle-Ottawa scale (NOS).Only randomised clinical trials (RCTs) were considered for meta-analysis. Implant failure and postoperative infection were the dichotomous outcomes measures evaluated. Weighted mean differences were used for MBL.

Results: Twenty-eight studies …

Comparison Of The Kois Dento-Facial Analyzer System With An Earbow For Mounting A Maxillary Cast, Laura H. Lux, Geoffrey A. Thompson, Kenneth J. Waliszewski, Gerald J. Ziebert

School of Dentistry Faculty Research and Publications

Statement of problem: The Kois Dento-Facial Analyzer System (KDFA) is used by clinicians to mount maxillary casts and evaluate and treat patients. Limited information is available for understanding whether the KDFA should be considered as an alternative to an earbow.

Purpose: The purpose of this study was to evaluate maxillary casts mounted using the KDFA with casts mounted using Panadent's Pana-Mount Facebow (PMF). Both articulation methods were compared against a lateral cephalometric radiograph.

Material and methods: Fifteen dried human skulls were used. Lateral cephalometric radiographs and 2 maxillary impressions were made of each skull. One cast from each skull was …

Intraosseous Sebaceous Adenocarcinoma Of The Maxilla, Deepthi Hoskoppal, Sohail Qayyum, Kenneth M. Anderson, Yeshwant B. Rawal

School of Dentistry Faculty Research and Publications

Primary intraosseous salivary malignancies are rare. The adenoid cystic adenocarcinoma, adenocarcinoma not otherwise specified, acinic cell adenocarcinoma and the epithelial-myoepithelial carcinoma have all been reported within the jaws. The mucoepidermoid carcinoma is by far the most common tumor in this setting accounting for 2%-4% of all mucoepidermoid carcinomas. An intraosseous sebaceous adenocarcinoma has never been reported. We document a case of sebaceous adenocarcinoma of the maxilla in a 56-year-old woman who presented with a painful swelling of the right face. CT scans showed an expansile, osteolytic tumor of the right maxilla. An exploratory biopsy revealed the tumor to be expanding …

Color-To-Grayscale Conversion Using A Smart Phone Camera For Value Comparison, Seok-Hwan Cho

School of Dentistry Faculty Research and Publications

No abstract provided.

Custom Total Occlusal Convergence Angle Sticker Fabrication, Seok-Hwan Cho, William W. Nagy

School of Dentistry Faculty Research and Publications

This article describes a method of fabricating a custom total occlusal convergence angle sticker with photo editing software and label stickers. The custom total occlusal convergence angle sticker can help clinicians achieve an accurate degree of taper during axial wall reduction of tooth preparation.

Development Of Optical Biosensor Technologies For Cardiac Troponin Recognition, Mojgan Abdolrahim, Mohammad Rabiee, Sanaz Naghavi Alhosseini, Mohammadreza Tahriri, Sara Yazdanpanah, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events. The cardiac troponin concentration level in blood has been shown to rise rapidly for 4–10 days after onset of AMI, making it an attractive approach for a long diagnosis window for detection. The extremely low clinical sensing range of cardiac troponin levels consequently makes the methods of detection highly sensitive. In this review, by taking into consideration optical methods applied for cardiac troponin detection, …

Fracture Resistance Of Compromised Endodontically Treated Teeth Restored With Bonded Post And Cores: An In Vitro Study, Georgios Maroulakos, William W. Nagy, Elias D. Kontogiorgos

School of Dentistry Faculty Research and Publications

Statement of problem: It is unclear which post and core system performs best when bonded to severely compromised endodontically treated teeth.

Purpose: The purpose of this study was to investigate the fracture resistance and mode of failure of severely compromised teeth restored with 3 different adhesively bonded post and core systems.

Material and methods: Thirty extracted endodontically treated maxillary anterior teeth were randomly divided into 3 groups, CPC, gold cast post and core; TPC, titanium prefabricated post/composite resin core; and FPC, quartz fiber reinforced post/composite resin core. All posts were adhesively cemented. All cores resembled a central incisor preparation with …

Using A Thermoplastic Sheet To Add Palatal Rugae To A Complete Removable Dental Prosthesis, Seok-Hwan Cho, William W. Nagy

School of Dentistry Faculty Research and Publications

No abstract provided.

Customized Occlusal Reduction Guide Made From A Thermoplastic Sheet, Seok-Hwan Cho, William W. Nagy

School of Dentistry Faculty Research and Publications

No abstract provided.

Induced Ankylosis Of A Primary Molar For Skeletal Anchorage In The Mandible As Alternative To Mini-Implants, Matina V. Angelopoulou, Despina Koletsi, George Vadiakas, Demetrios J. Halazonetis

School of Dentistry Faculty Research and Publications

Background

Mesial protraction of mandibular posterior teeth requires increased anchorage to avoid undesired tooth movements. Orthodontic mini-implants have become a popular and successful way to increase skeletal anchorage in such cases. However, mini-implants may cause injury to adjacent teeth or anatomical structures and may lead to tissue inflammation. Induced ankylosed primary teeth have been used in the past as abutments for the protraction of the maxilla in cases of maxillary retrognathism. However, this technique has not been described in the literature for the protraction of mandibular molars. The aim of this paper is to present, through a case report, an …

Desmoplastic Fibroma Of The Mandible: A Series Of Three Cases And Review Of Literature, T. R. Woods, D. M. Cohen, M. N. Islam, Yeshwant B. Rawal, I. Bhattacharyya

School of Dentistry Faculty Research and Publications

The desmoplastic fibroma (DF) is a rare, fibroblastic lesion of bone that histologically resembles the desmoid tumor of soft tissue. Although classified as benign, it frequently demonstrates aggressive behavior, often causing tooth mobility, extensive bone destruction, and has a moderate to high recurrence rate. We present three cases of DF in the mandible: the first in a 13 year old female involving the mandibular body in the region of teeth #s 27–#28, the second in a 57 year old female with a lesion apical to tooth #30, and the third in a 20-year-old female involving the left posterior mandible. Clinical, …

Morphologic Custom Shade Guide Fabricated With Feldspathic Ceramic, Seok-Hwan Cho, William W. Nagy

School of Dentistry Faculty Research and Publications

No abstract provided.

Congenital Adrenal Hyperplasia: A Case Report With Premature Teeth Exfoliation And Bone Resorption, Matina V. Angelopoulou, Elias D. Kontogiorgos, Dimitris E. Emmanouil

School of Dentistry Faculty Research and Publications

Congenital adrenal hyperplasia (CAH) is an inherited autosomal recessive disorder characterized by insufficient production of cortisol. The aim of this case report was to present a child with CAH, premature exfoliation of primary teeth and accelerated eruption of his permanent teeth related to bone resorption. A 4.5-year-old Caucasian boy with CAH and long-term administration of glucocorticoids was referred for dental restoration. Clinical examination revealed primary molars with worn stainless steel crowns, severe attrition of the upper canines, and absence of the upper incisors. Before the completion of treatment, abnormal mobility of the first upper primary molars and the lower incisors …

Die Spacer Thickness Reproduction For Central Incisor Crown Fabrication With Combined Computer-Aided Design And 3d Printing Technology: An In Vitro Study, Lisa N. Hoang, Geoffrey A. Thompson, Seok-Hwan Cho, David W. Berzins, Kwang Woo Ahn

School of Dentistry Faculty Research and Publications

Statement of problem

The inability to control die spacer thickness has been reported. However, little information is available on the congruency between the computer-aided design parameters for die spacer thickness and the actual printout.

Purpose

The purpose of this study was to evaluate the accuracy and precision of the die spacer thickness achieved by combining computer-aided design and 3-dimensional printing technology.

Material and Methods

An ivorine maxillary central incisor was prepared for a ceramic crown. The prepared tooth was duplicated by using polyvinyl siloxane duplicating silicone, and 80 die-stone models were produced from Type IV dental stone. The dies were …

Effect Of Different Thicknesses Of Pressable Ceramic Veneers On Polymerization Of Light-Cured And Dual-Cured Resin Cements, Seok-Hwan Cho, Arnaldo Lopez, David W. Berzins, Soni Prasad, Kwang Woo Ahn

School of Dentistry Faculty Research and Publications

Aim: This study evaluated the effects of ceramic veneer thicknesses on the polymerization of two different resin cements.

Materials and methods: A total of 80 ceramic veneer disks were fabricated by using a pressable ceramic material (e.max Press; Ivoclar Vivadent) from a Low Translucency (LT) ingot (A1 shade). These disks were divided into light-cured (LC; NX3 Nexus LC; Kerr) and dual-cured (DC; NX3 Nexus DC; Kerr) and each group was further divided into four subgroups, based on ceramic disk thickness (0.3, 0.6, 0.9, and 1.2 mm). The values of Vickers microhardness (MH) and degree of conversion (DOC) were obtained for …

Oral Hygiene Facilitators And Barriers In Greek 10 Years Old Schoolchildren, Matina V. Angelopoulou, Katerina Kavvadia, Constantine Oulis, Christina Reppa

School of Dentistry Faculty Research and Publications

Aim: The aim of this study was to determine the oral hygiene facilitators and barriers for 10 years old Greek children, via a questionnaire and clinical examination.

Materials and Methods: This was a cross-sectional study of 266, 10 years old, children recruited from schools in 3 locations in Greece. Data were collected via questionnaires and clinical examination. Questionnaires referred to children's oral hygiene knowledge, behavior and attitude as well as parents' oral hygiene behavior and educational level. Children were clinically examined by two calibrated pediatric dentists using a WHO probe and artificial light to assess dental plaque (hygiene index-HI), gingivitis …

Comparative Clinical Study Testing The Effectiveness Of School Based Oral Health Education Using Experiential Learning Or Traditional Lecturing In 10 Year-Old Children, Matina V. Angelopoulou, Katerina Kavvadia, Konstantina Taoufik, Constantine J. Oulis

School of Dentistry Faculty Research and Publications

Background: School based oral health education through traditional lecturing has been found successful only in improving oral health knowledge, while has low effectiveness in oral hygiene and gingival health. The aim of this study was to evaluate the effectiveness of experiential learning (EL) oral health education to traditional lecturing (TL), on enhancing oral health knowledge, attitude and behavior as well as oral hygiene, gingival health and caries of 10-year-old children.

Methods: Eighty-four children were recruited for the EL and 100 for the TL group from 3 locations in Greece. Data regarding oral health knowledge, attitude and behavior were …

Comparative Clinical Study Testing The Effectiveness Of School Based Oral Health Education Using Experiential Learning Or Traditional Lecturing In 10 Year-Old Children, Matina V. Angelopoulou, Katerina Kavvadia, Konstantine Taoufik, Constantine J. Oulis

School of Dentistry Faculty Research and Publications

Background

School based oral health education through traditional lecturing has been found successful only in improving oral health knowledge, while has low effectiveness in oral hygiene and gingival health. The aim of this study was to evaluate the effectiveness of experiential learning (EL) oral health education to traditional lecturing (TL), on enhancing oral health knowledge, attitude and behavior as well as oral hygiene, gingival health and caries of 10-year-old children.

Methods

Eighty-four children were recruited for the EL and 100 for the TL group from 3 locations in Greece. Data regarding oral health knowledge, attitude and behavior were collected via …

Quality Of Postoperative Pain Management After Midfacial Fracture Repair—An Outcome-Oriented Study, Gregor F. Raschke, Andre Peisker, Ulrich M. Rieger, Gabriel Djedovic, Arndt Guentsch, Oliver Schaefer, Eric Venth, Marta Gomez-Dammeier, Winfried Meissner

School of Dentistry Faculty Research and Publications

Objectives

There is a lack of literature regarding the procedure-specific quality of acute postoperative pain management after midfacial fracture repair. The purpose of the presented prospective clinical study was to evaluate postoperative pain management after surgical repair of midfacial fractures.

Materials and methods

Eighty-five adults were evaluated on the first postoperative day following midfacial repair using the questionnaire of the Quality Improvement in Postoperative Pain Management (QUIPS) project. The main outcome measures were patients’ characteristics and clinical- and patient-reported outcome parameters.

Results

Overall, pain on the first postoperative day was moderate. A significant correlation between process and outcome parameters could …

Surface Modification Of Biodegradable Porous Mg Bone Scaffold Using Polycaprolactone/Bioactive Glass Composite, Mostafa Yazdimamaghani, Mehdi Razavi, Daryoosh Vashaee, Lobat Tayebi

School of Dentistry Faculty Research and Publications

A reduction in the degradation rate of magnesium (Mg) and its alloys is in high demand to enable these materials to be used in orthopedic applications. For this purpose, in this paper, a biocompatible polymeric layer reinforced with a bioactive ceramic made of polycaprolactone (PCL) and bioactive glass (BG) was applied on the surface of Mg scaffolds using dip-coating technique under low vacuum. The results indicated that the PCL-BG coated Mg scaffolds exhibited noticeably enhanced bioactivity compared to the uncoated scaffold. Moreover, the mechanical integrity of the Mg scaffolds was improved using the PCL-BG coating on the surface. The stable …