Medicine and Health Sciences Commons^™

The Absence Of Cd20 Messenger Rna In Recurrent Cutaneous B-Cell Lymphoma Following Rituximab Therapy, Yeshwant B. Rawal, Gerard J. Nuovo, Gwyn E. Frambach, Pierluigi Porcu, Robert A. Baiocchi, Cynthia M. Magro

School of Dentistry Faculty Research and Publications

Background: Rituximab has been used to treat relapsed low-grade or advanced non-Hodgkin's lymphoma since 1997, targeting the CD20 antigen expressed by B cells. Single-agent rituximab therapy is safe and well tolerated. Recurrences showing a loss of CD20 expression following rituximab therapy have been reported.

Methods: Four patients with CD20-positive cutaneous B-cell lymphoma received rituximab therapy with subsequent recurrences. The biopsies were assessed for cytoplasmic CD20 expression; CD20 messenger RNA was also assessed where tissue was available.

Results: Cutaneous relapses occurring within 1.5–3 months following the last dose of rituximab were CD20 negative. In three cases, subsequent relapses showed renewed expression …

Presentation Of An Epithelioid Cell Histiocytoma On The Ventral Tongue, Yeshwant B. Rawal, John R. Kalmar, Brian S. Shumway, Susan R. Mallery

School of Dentistry Faculty Research and Publications

The epithelioid cell histiocytoma (ECH) is a polypoidal benign tumor of superficial connective tissue that is often diagnosed as a pyogenic granuloma. ECHs are speculated to originate from dermal dendritic subunits and are composed of 2 primary cell populations, ie, CD34⁺ primitive fibroblastic dendrocytes and factor XIIIa⁺ histiocytes. Although dendritic subunits are distributed throughout most collagenous tissues inclusive of oral mucosa, to date, all reported cases of ECH have been cutaneous lesions. ECHs' putative pathogenesis entails activation of CD34⁺ “sentinel” reserve dendrocytes, followed by an influx of histiocytes and mast cells. Juxtacrine communication increases release of wound …

Treatment Of The Prominent Mandibular Angle By Using A Custom Made Surgical Splint, Luis Eduardo Almeida, Kingsley Wang, Davani Costa, Marco Antonio De Oliveira Filho

School of Dentistry Faculty Research and Publications

In this case report, we would like to present an alternative surgical technique for the treatment of the bilateral prominent mandibular angles by using a custom-made resin splint (template). The prefabricated template provided a precise outline for the osteotomy, which alleviated the uncertainty of the osseous cut. Furthermore, masseter muscle myomectomy was not necessary in this case which decreased morbidity, and procedure and recovery time, while assuring a more symmetric outcome.

Prevention Of Periodontal Diseases, Andrew R. Dentino, Moawia M. Kassab, Erica J. Renner

School of Dentistry Faculty Research and Publications

No abstract provided.

Palatal Perforation Associated With Intranasal Prescription Narcotic Abuse, Wendi M. Jewers, Yeshwant B. Rawal, Carl M. Allen, John R. Kalmar, Eric Fox, Guillermo E. Chacon, Parish P. Sedghizadeh

School of Dentistry Faculty Research and Publications

Background

Palatal perforation resulting from insufflation of cocaine has been well documented. In comparison, reports of destructive orofacial lesions resulting from intranasal abuse of prescription narcotics are rare. We present the clinical and histologic findings in a case of palatal perforation arising in a patient abusing a prescription opioid drug. The patient denied any history of cocaine use but admitted to habitually crushing and snorting a hydrocodone/acetaminophen preparation.

Study design

The patient presented to our clinic seeking resolution of speech difficulties associated with an oroantral fistula. Surgical repair of the defect had been attempted unsuccessfully in the past. In addition …

Adhesive Fragment Reattachment After Orthodontic Extrusion: A Case Report, S. Burcak Cengiz, Ilken Kocadereli, H. Cem Güngör, Nil Altay

School of Dentistry Faculty Research and Publications

In the treatment of crown fractures, adhesive fragment reattachment provides a good alternative to other restorative techniques, offering several advantages. The present paper reports a case in which the treatment of a cervical crown fracture was accomplished by reattaching the tooth fragment with a flowable resin composite. Orthodontic root extrusion was performed with a modified Hawley appliance prior to fragment reattachment. The clinical and radiographic results after 2.5 years were successful.

Pilot Survey Of Oral Health-Related Quality Of Life: A Cross-Sectional Study Of Adults In Benin City, Edo State, Nigeria, Christopher Okunseri, Amit Chattopadhyay, R Iván Lugo, Colman Mcgrath

School of Dentistry Faculty Research and Publications

Background

Oral health studies conducted so far in Nigeria have documented prevalence and incidence of dental disease using traditional clinical measures. However none have investigated the use of an oral health-related quality of life (OHRQoL) instrument to document oral health outcomes. The aims of this study are: to describe how oral health affects and impacts quality of life (QoL) and to explore the association between these affects and the oral health care seeking behavior of adults in Benin City, Edo State, Nigeria.

Methods

A cross-sectional survey recruited 356 adults aged 18–64 years from two large hospital outpatient departments and from …