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Full-Text Articles in Medicine and Health Sciences
Position Of Γ-Chain Carboxy-Terminal Regions In Fibrinogen/Fibrin Cross-Linking Mixtures, Kevin R. Siebenlist, David A. Meh, Michael W. Mosesson
Position Of Γ-Chain Carboxy-Terminal Regions In Fibrinogen/Fibrin Cross-Linking Mixtures, Kevin R. Siebenlist, David A. Meh, Michael W. Mosesson
Biomedical Sciences Faculty Research and Publications
There are conflicting ideas regarding the location of the carboxyl-terminal regions of cross-linked γ-chain dimers in double-stranded fibrin fibrils. Some investigators believe that the chains are always oriented longitudinally along each fibril strand and traverse the contacting ends of abutting fibrin D domains (“DD-long” cross-linking). Other investigations have indicated instead that the chains are situated transversely between adjacent D domains in opposing fibril strands (transverse cross-linking). To distinguish between these two possibilities, the γ dimer composition of factor XIIIa-cross-linked fibrin/fibrinogen complexes that had been formed through noncovalent D/E interactions between fibrinogen D domains and fibrin E domains was examined. Two …
Evaluation Of Online Course Discussions: Faculty Facilitation Of Active Student Learning, Leona Vandevusse, Lisa Hanson
Evaluation Of Online Course Discussions: Faculty Facilitation Of Active Student Learning, Leona Vandevusse, Lisa Hanson
College of Nursing Faculty Research and Publications
Graduate nursing faculty evaluated their initial experiences with online course discussions after making the transition from traditional use of weekly face-to-face classroom discussions to primarily computer-based interactions with students at distant sites. The online discussion data were analyzed qualitatively. The ways the faculty member communicated to facilitate active student involvement in the online discussions were coded. Six categories were identified that describe the ways the faculty member communicated to facilitate active student involvement in online discussions: assist with navigation, explain expectations, clarify faculty role, stimulate critical thinking, share expertise, and provide encouragement. Examples of each were provided to demonstrate ways …
Large-Scale Synthesis And Functional Elements For The Antimicrobial Activity Of Defensins, Periathamby A. Raj, K. J. Antonyraj, T. Karunakaran
Large-Scale Synthesis And Functional Elements For The Antimicrobial Activity Of Defensins, Periathamby A. Raj, K. J. Antonyraj, T. Karunakaran
School of Dentistry Faculty Research and Publications
Human neutrophil defensins, and their analogues incorporating anionic, hydrophobic or cationic residues at the N- and C-termini, were synthesized by solid-phase procedures. The synthetic defensins were examined for their microbicidal activity against Candida albicans, two Gram-negative bacteria (Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis) and two Gram-positive bacteria (Streptococcus gordonii and Streptococcus mutans). The human neutrophil peptide 1 (HNP1) and HNP2 were found to be potent candidacidal agents. HNP3, which differs by one amino acid at the N-terminus of its sequence, was totally inactive. The Gram-negative bacteria A. actinomycetemcomitans and P. gingivalis and the Gram-positive bacteria S. gordonii and S. mutans were …
Relationship Between Scholastic And Health Behaviors And Reading Level In Adolescent Females, Steven C. Matson, Kristin Haglund
Relationship Between Scholastic And Health Behaviors And Reading Level In Adolescent Females, Steven C. Matson, Kristin Haglund
College of Nursing Faculty Research and Publications
This was a study of 102 adolescent females, 12-20 years of age, presenting to a central city clinic for medical care. Participants completed an oral questionnaire that included demographics, and questions regarding scholastic history, sexual behavior, and substance use. Each subject completed the Accuracy Level Test (ALT), a reading test. The subject's reading test grade level was subtracted from her appropriate grade in school to give a reading delay level (RDL). The mean reading grade level for all subjects was 6.7 ±2.6 and the average reading delay was 4.5 ±2.5 grades. Poor school attenders had greater reading delays (5.8 ±3.4 …
Parenting A Second Time Around: An Ethnography Of African American Grandmothers Parenting Grandchildren Due To Parental Cocaine Abuse, Kristin Haglund
Parenting A Second Time Around: An Ethnography Of African American Grandmothers Parenting Grandchildren Due To Parental Cocaine Abuse, Kristin Haglund
College of Nursing Faculty Research and Publications
This study describes a group of six African American grandmothers parenting their grandchildren secondary to cocaine abuse on the part of the parents. It explores the manner in which such parenting affected the grandmothers’ health. Data for this ethnography design were collected through participant observation, field notes, taped interviews, and supplementary data sources. The identification of cultural themes evolved from domain and taxonomic analyses. The themes—parenting a second time around, sacrifice, and God’s presence in daily life—expressed aspects of the grandmothers’ culture. The effects on health varied from none to exacerbation of chronic illnesses. The study results, and its picture …
Cytokines And The Anorexia Of Infection: Potential Mechanisms And Treatments, Donna O. Mccarthy
Cytokines And The Anorexia Of Infection: Potential Mechanisms And Treatments, Donna O. Mccarthy
College of Nursing Faculty Research and Publications
Anorexia during infection is thought to be mediated by immunoregulatory cytokines such as interleukins 1 and 6 and tumor necrosis factor. This article reviews the potential mechanisms of action by which these cytokines are thought to suppress food intake during infection and examines the proposition that blocking of cytokine activity might be one approach to improving food intake of the infected host.
Pulpal Tissue In Bilateral Talon Cusps Of Primary Central Incisors: Report Of A Case, H. Cem Güngör, Nil Altay, F. Figen Kaymaz
Pulpal Tissue In Bilateral Talon Cusps Of Primary Central Incisors: Report Of A Case, H. Cem Güngör, Nil Altay, F. Figen Kaymaz
School of Dentistry Faculty Research and Publications
Talon cusp is a tooth anomaly that affects both the primary and the permanent dentitions. However, the occurrence of this anomalous cusp is rather infrequent in the primary dentition. Only 7 cases of bilateral talon cusps affecting the primary teeth have been reported in the dental literature. This is a case report of bilateral talon cusps on primary maxillary central incisors whose histologic evaluation revealed the existence of pulpal tissue in the anomalous cusps.
The Effect Of Edta In Attachment Gain And Root Coverage, Moawia M. Kassab, Robert E. Cohen, Sebastiano Andreana, Andrew R. Dentino
The Effect Of Edta In Attachment Gain And Root Coverage, Moawia M. Kassab, Robert E. Cohen, Sebastiano Andreana, Andrew R. Dentino
School of Dentistry Faculty Research and Publications
Root surface biomodification using low pH agents such as citric acid and tetracycline has been proposed to enhance root coverage following connective tissue grafting. The authors hypothesized that root conditioning with neutral pH edetic acid would improve vertical recession depth, root surface coverage, pocket depth, and clinical attachment levels. Twenty teeth in 10 patients with Miller class I and II recession were treated with connective tissue grafting. The experimental sites received 24% edetic acid in sterile distilled water applied to the root surface for 2 minutes before grafting. Controls were pretreated with only sterile distilled water. Measurements were evaluated before …
Effects Of Electrical Stimulation On Wound Closure In Mice With Experimental Diabetes Mellitus, Habiba A. Thawer, Pamela E. Houghton, Luther Kloth, Anna Butryn
Effects Of Electrical Stimulation On Wound Closure In Mice With Experimental Diabetes Mellitus, Habiba A. Thawer, Pamela E. Houghton, Luther Kloth, Anna Butryn
Physical Therapy Faculty Research and Publications
The purpose of the present study was to examine the effect of electrical stimulation (ES) on the closure of full-thickness excisional wounds in mice with type-1 experimental diabetes mellitus (DM). Alloxon monohydrate (100mg/kg) was used to induce experimental DM in mole CD-1 mice (n = 88). Full-thickness skin excisions (1cm2) in diabetic (urine glucose > 0) and non-diabetic (urine glucose = 0) mice were administered 1, 3, or 5 treatments of ES (200μs, 200 Hz) for 15 minutes, at 0 (sham), 5, 10, or 12.5 volts. Alloxon injection resulted in a positive urine glucose test in 48 mice yielding …
Whole Body Momentum During Gait: A Preliminary Study Of Non-Fallers And Frequent Fallers, Guy G. Simoneau, David E. Krebs
Whole Body Momentum During Gait: A Preliminary Study Of Non-Fallers And Frequent Fallers, Guy G. Simoneau, David E. Krebs
Physical Therapy Faculty Research and Publications
The importance of momentum in compensating for elderly individua ls ' strength deficits to achieve activities of daily living. such as rising from a chair ha.!o been demonstrated in earlier studies. Here we present a case control study of three healthy "non-fallers" and two "frequent fallers," All 5 elders were community-living and were tested in the gai l laboratory. A four-camera Selspot system was used to obtain whole-body momentum from an 11-segment kinematic model. Ground reaction forces and kinematics were used 10 calculate lower extremity join! moments. With the exception of the whole-body's angular momentum about the vertical axis, linear …
Anthropological Differences Between Contraception And Natural Family Planning, Richard Fehring, William Kurz
Anthropological Differences Between Contraception And Natural Family Planning, Richard Fehring, William Kurz
College of Nursing Faculty Research and Publications
Almost twenty years ago, Pope John Paul II in his apostolic exhortation Familiaris Consortio called on scholars to study the anthropological and moral differences between the recourse to the natural rhythms of a woman’s menstrual cycle (i.e., natural family planning) and contraception (1). Although natural family planning (NFP) and contraception can both be used to prevent pregnancy, there are conspicuous differences between use of natural methods and contraception. Most people, however, have difficulty in distinguishing what the differences are and in understanding why some religious groups, health professionals, and other members of society consider contraception (but not natural family planning) …
Through The Eye Of The Beholder: Multiple Perspectives On Quality In Women's Health Care, Jaynelle F. Stichler, Marianne E. Weiss
Through The Eye Of The Beholder: Multiple Perspectives On Quality In Women's Health Care, Jaynelle F. Stichler, Marianne E. Weiss
College of Nursing Faculty Research and Publications
Quality is an illusive concept with different meanings to different people. Providers often define quality in terms of patient outcomes, professional standards of practice, predetermined criteria used to measure quality, and even subjective opinion. Patients describe quality in terms of the interpersonal aspects of care, how well they were treated, and the responsiveness of the provider to their needs. This qualitative study using a semi-structured interview defined quality from the perspectives of patients, physicians, nurses, and payers associated with a hospital-based women's service line, and how the attributes of quality varied among the multiple groups. The study also described how …