Medicine and Health Sciences Commons^™

The Role Of Candidate-Gene Cntnap2 In Childhood Apraxia Of Speech And Specific Language Impairment, Tracy M. Centanni, J. N. Sanmann, J. R. Green, Jenya Iuzzini-Seigel, Christopher W. Bartlett, W. G. Sanger, Tiffany P. Hogan

Speech Pathology and Audiology Faculty Research and Publications

Childhood apraxia of speech (CAS) is a debilitating pediatric speech disorder characterized by varying symptom profiles, comorbid deficits, and limited response to intervention. Specific Language Impairment (SLI) is an inherited pediatric language disorder characterized by delayed and/or disordered oral language skills including impaired semantics, syntax, and discourse. To date, the genes associated with CAS and SLI are not fully characterized. In the current study, we evaluated behavioral and genetic profiles of seven children with CAS and eight children with SLI, while ensuring all children were free of comorbid impairments. Deletions within CNTNAP2 were found in two children with CAS but …

Reliance On Auditory Feedback In Children With Childhood Apraxia Of Speech, Jenya Iuzzini-Seigel, Tiffany P. Hogan, Anthony J. Guarino, Jordan R. Green

Speech Pathology and Audiology Faculty Research and Publications

Children with childhood apraxia of speech (CAS) have been hypothesized to continuously monitor their speech through auditory feedback to minimize speech errors. We used an auditory masking paradigm to determine the effect of attenuating auditory feedback on speech in 30 children: 9 with CAS, 10 with speech delay, and 11 with typical development. The masking only affected the speech of children with CAS as measured by voice onset time and vowel space area. These findings provide preliminary support for greater reliance on auditory feedback among children with CAS.

Learning outcomes: Readers of this article should be able to (i) …