Medicine and Health Sciences Commons^™

Mechanical Properties Of Natural Chitosan/Hydroxyapatite/Magnetite Nanocomposites For Tissue Engineering Applications, Fatemeh Heidari, Mehdi Razavi, Mohammad E. Bahrololoom, Reza Bazargan-Lari, Daryoosh Vashaee, Hari Kotturi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Chitosan (CS), hydroxyapatite (HA), and magnetite (Fe₃O₄) have been broadly employed for bone treatment applications. Having a hybrid biomaterial composed of the aforementioned constituents not only accumulates the useful characteristics of each component, but also provides outstanding composite properties. In the present research, mechanical properties of pure CS, CS/HA, CS/HA/magnetite, and CS/magnetite were evaluated by the measurements of bending strength, elastic modulus, compressive strength and hardness values. Moreover, the morphology of the bending fracture surfaces were characterized using a scanning electron microscope (SEM) and an image analyzer. Studies were also conducted to examine the biological response …