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Full-Text Articles in Medicine and Health Sciences
Amelioration Of Oral Mucositis Pain By Nasa Near Infra Red Light Emitting Diodes In Bone Marrow Transplant Patients, Brian Hodgson, David Margolis, Donna E. Salzman, Dan C. Eastwood, Sergey Tarima, Lisa D. Williams, Jane E. Sande, William P. Vaughan, Harry T. Whelan
Amelioration Of Oral Mucositis Pain By Nasa Near Infra Red Light Emitting Diodes In Bone Marrow Transplant Patients, Brian Hodgson, David Margolis, Donna E. Salzman, Dan C. Eastwood, Sergey Tarima, Lisa D. Williams, Jane E. Sande, William P. Vaughan, Harry T. Whelan
School of Dentistry Faculty Research and Publications
PURPOSE: To investigate the use of extra-orally applied near infra-red (NIR) phototherapy for the reduction of oral pain secondary to chemo- and radiation-therapy induced mucositis in adult and pediatric hematopoietic stem cell transplant (HSCT) patients.
METHODS: 80 HSCT were divided into regular (R) and low (L) risk groups, then to experimental (E) and placebo (P) groups, resulting in 4 groups (ER, EL, PR, PL). Experimental subjects received (670 (+/- 10) nm gallium-aluminum-arsinide light emitting diode (LED) device for 80 sec at an ~50mW/cm2 energy density and power exposure of 4J/cm2. Placebo patients received the same procedures, but with a placebo …