Medicine and Health Sciences Commons^™

A Systematic Review Of Dental Disease In Patients Undergoing Cancer Therapy, Catherine H.L. Hong, Joel J. Napeñas, Brian D. Hodgson, Monique A. Stokman, Vickie Mathers-Stauffer, Linda S. Elting, Fred K.L. Spijkervet, Michael T. Brennan

School of Dentistry Faculty Research and Publications

Introduction: The purpose of this systematic review was to evaluate the literature and update our current understanding of the impact of present cancer therapies on the dental apparatus (teeth and periodontium) since the 1989 NIH Development Consensus Conference on the Oral Compli­cations of Cancer Therapies.

Review Method: A systematic literature search was con­ducted with assistance from a research librarian in the databases MEDLINE/PubMed and EMBASE for articles published between 1 January 1990 and 31 December 2008. Each study was independently assessed by two reviewers. Taking into account predetermined quality measures, a weighted prevalence was calculated for the prevalence of dental …