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Articles 1 - 15 of 15
Full-Text Articles in Medicine and Health Sciences
Evaluation Of Clinical Growth And Nursing Student Motivation In The Traditional Clinical Learning Environment, Jessica Barkimer
Evaluation Of Clinical Growth And Nursing Student Motivation In The Traditional Clinical Learning Environment, Jessica Barkimer
Dissertations (1934 -)
Evaluation of students in the traditional clinical learning environment is difficult. There remains a lack of standard guidelines to evaluate students using valid and reliable instruments as well as inconsistent processes with lack of interrater reliability standards between educators. A need exists for fair and consistent evaluation of nursing students. When the clinical educator uses a standard evaluation process and understands students’ motivation for learning, adaptations in teaching strategies and education on self-regulatory strategies can be implemented to enhance learning and measure clinical growth. This research study used a prospective, correlational, pre-test/post-test design to examine the relationship between student motivation …
Comparing Interprofessional Socialization In Mixed Discipline And Nursing Student Only Cohorts, Kara Groom
Comparing Interprofessional Socialization In Mixed Discipline And Nursing Student Only Cohorts, Kara Groom
Dissertations (1934 -)
A main cause of patient safety incidents are avoidable failures in communication between health professionals. In response, healthcare has entered an era of interprofessionalism in education and patient care. A challenge to substantiating the value of interprofessional education (IPE) has been a limited number of studies that assess the effectiveness of IPE interventions compared to education interventions in which professions were learning separately from one another. This research project helps fill this gap and measures the differences in student interprofessional socialization (IS) between an IPE cohort and a usual care group of one-discipline learners. The purpose was to compare IS …
Home Health Care Effect In Post-Discharge Return To Hospital, Danielle M. Siclovan
Home Health Care Effect In Post-Discharge Return To Hospital, Danielle M. Siclovan
Dissertations (1934 -)
Background: Home Health Care (HHC), the most commonly used bridge strategy for transitioning from hospital to home-based care, is expected to contribute to ongoing readmission avoidance efforts. However, evidence suggests HHC patients are readmitted more frequently than patients without HHC. Determining the effectiveness of HHC as a readmission reduction strategy requires a comparison sample of patients with similar characteristics referred and not referred to HHC. Methods: For this matched-sample comparative study, the available sample (n=18,774) included 3,629 patients referred to HHC and 15,145 non-HHC patients, from which 2,718 pairs matched 1:1 were obtained using exact and Mahalanobis distance matching. Unadjusted …
Qualitative Exploration Of The Perceptions Of Nursing Undergraduates Regarding Family Care At End-Of-Life, Penny A. Alt-Gehrman
Qualitative Exploration Of The Perceptions Of Nursing Undergraduates Regarding Family Care At End-Of-Life, Penny A. Alt-Gehrman
Dissertations (1934 -)
Background/Purpose: Family care at end-of-life is delivered by nurses and includes communication and explanations, providing emotional support for the family, creating an environment in which death occurs with dignity, providing privacy, facilitating visitation, and honoring and meeting cultural and personal family values (Beckstrand et al., 2011; Bloomer et al., 2013; Cronin et al., 2015; Heidari & Norouzadeh, 2014). There appears to be a gap in the empirical evidence and literature on this topic. Regarding the knowledge and comfort of student nurses, and subsequently nurses, in family care at the end-of-life, there is disparity. To determine what must be taught to …
Understanding Water Diffusion In Experimental Spinal Cord Injury Remote From Injury Epicenter, Alice Motovylyak
Understanding Water Diffusion In Experimental Spinal Cord Injury Remote From Injury Epicenter, Alice Motovylyak
Dissertations (1934 -)
Diffusion tensor imaging (DTI) has demonstrated success as a biomarker of spinal cord injury (SCI) severity as shown from numerous preclinical studies. However, artifacts from stabilization hardware at the lesion have precluded its use for longitudinal assessments. Previous research has documented ex vivo diffusion changes in the spinal cord both caudal and rostral to the injury epicenter. The aim of this dissertation was to quantify the structural changes that lead to different diffusion measures in the rat cervical spinal cord after a thoracic contusion injury in an attempt to find a biomarker of injury. Animals received a thoracic contusion injury …
Understanding Relationships Between Early Life Toxic Stress, Childhood Socioeconomic Disadvantage, And Allostatic Load In Adolescence, Amanda King
Dissertations (1934 -)
Chronic disease prevalence among children and adolescents is rising, which is thought to result in part from elevations in allostatic load (AL). AL is the cumulative physiological dysregulation that results from exposure to biological, social and environmental stressors over time. Socioeconomic disparities in chronic disease and AL have been well-documented in adult populations, including links between childhood socioeconomic disadvantage (CSD) and AL, yet little is known as to whether CSD may begin to impact AL earlier in life. Differential exposure and vulnerability to stress among racial/ethnic minorities may increase risk for elevated AL among those experiencing CSD. Framed by the …
Inference And Analysis Of Multilayered Mirna-Mediated Networks In Cancer, Duc Do
Inference And Analysis Of Multilayered Mirna-Mediated Networks In Cancer, Duc Do
Dissertations (1934 -)
MicroRNAs (miRNAs) are small noncoding transcripts that can regulate gene expression, thereby controlling diverse biological processes. Aberrant disruptions of miRNA expression and their interactions with other biological agents (e.g., coding and noncoding transcripts) have been associated with several types of cancer. The goal of this dissertation is to use multidimensional genomic data to model two different gene regulation mechanisms by miRNAs in cancer. This dissertation results from two research projects. The first project investigates a miRNA-mediated gene regulation mechanism called competing endogenous RNA (ceRNA) interactions, which suggests that some transcripts can indirectly regulate one another's activity through their interactions with …
Pre-Death Grief, Resourcefulness And Perceived Stress Among Care Givers Of Partners With Young Onset Dementia, Karie Kobiske
Pre-Death Grief, Resourcefulness And Perceived Stress Among Care Givers Of Partners With Young Onset Dementia, Karie Kobiske
Dissertations (1934 -)
Over 200,000 Americans are diagnosed with young onset dementia (YOD). YOD is the dementia diagnosed prior to the age of 65. Most persons of YOD are cared for by their partners. Caregiving for a partner diagnosed with YOD has unique challenges including multiple losses resulting from the functional, cognitive, and behavioral declines which can be demanding and stressful. These losses experienced by the caregiver of a partner diagnosed with YOD have been termed pre-death grief. Caregivers of partners with YOD often report high levels of burden and stress resulting in depression, anxiety, hopelessness, as well as increase morbidity and mortality. …
Change In Bone Mineral Density Among High Frequency Apheresis Blood Donors, Walter Bialkowski
Change In Bone Mineral Density Among High Frequency Apheresis Blood Donors, Walter Bialkowski
Dissertations (1934 -)
Exposure to citrate anticoagulant during apheresis blood donation induces significant decreases in serum ionized calcium with subsequent perturbations to parathyroid hormone, vitamin D, and markers of bone remodeling. Cross-sectional studies of bone mineral density (BMD) among apheresis donors exhibit conflicting results. Resolving the potential impact of the highest apheresis donation frequency represents a significant knowledge gap in ensuring adequate protections for volunteer apheresis blood donors. ALTRUYST (NCT02655055) was a randomized, longitudinal, controlled clinical trial designed to determine if repeated exposure to citrate through apheresis donation reduces BMD. Male donors, 18-65 years of age with no more than five previous apheresis …
Motor Compensation During Lower Limb Pedaling After Stroke, Brice Thomas Cleland
Motor Compensation During Lower Limb Pedaling After Stroke, Brice Thomas Cleland
Dissertations (1934 -)
Long-term motor dysfunction in the lower limb is common after stroke. One potential contributor is motor compensation, a behavior in which functions originally performed by the paretic limb are performed by the non-paretic limb. Compensation in chronic stroke may contribute to long-term motor dysfunction by limiting functional ability, impairing future recovery, and eliciting maladaptive neuroplasticity. The purpose of this dissertation was to describe the impact of compensation on motor function and brain activation during lower limb pedaling and identify elements that produce this behavior. To achieve this purpose, we evaluated muscle activation and motor performance when compensation was prevented. During …
Mechanisms Of Fatigue With Aging: Evidence From The Whole-Limb To The Single Cell In Humans, Christopher W. Sundberg
Mechanisms Of Fatigue With Aging: Evidence From The Whole-Limb To The Single Cell In Humans, Christopher W. Sundberg
Dissertations (1934 -)
Aging is accompanied by a loss of muscle mass and increased fatigability of limb muscles making it difficult for old adults to generate the force and power necessary to perform daily activities, such as ascending a flight of stairs. The mechanisms for the age-related increase in fatigability in old and very old adults (≥80 yrs) and whether there are differences between men and women are unknown. The purpose of this dissertation was to determine the mechanisms for the age-related increase in fatigability in men and women by studying fatigue at the level of the whole-limb and within the muscle cells. …
The Impact Of Advance Directives On The Intensity Of Care Received In The Acute Care Setting In Older Adults, Marsha Helen Tyacke
The Impact Of Advance Directives On The Intensity Of Care Received In The Acute Care Setting In Older Adults, Marsha Helen Tyacke
Dissertations (1934 -)
The proportion of older adults in the U.S. is rapidly increasing. One-third of Medicare expenditures occur in the final year of life, with nearly half resulting from acute exacerbations of chronic, progressive diseases(Riley & Lubitz, 2010). Older adults prefer comfort over life-sustaining care, and decreased intensity of care is associated with improved quality of life at the end-of-life (EOL). Advance directives (ADs) have been proposed as mechanisms to improve congruence between patient wishes and EOL care; however, the impact of ADs on care delivered in the acute care setting at the EOL for this population is unclear. A retrospective, correlation …
Chronic Stress And Reproductive Function In Female Childhood Cancer Survivors, Theresa Marie Hardy
Chronic Stress And Reproductive Function In Female Childhood Cancer Survivors, Theresa Marie Hardy
Dissertations (1934 -)
Reproductive dysfunction is reported as a major concern for childhood cancer survivors (CCS) and is highly correlated with quality of life in this population. Few predictors of post-treatment reproductive function in CCS have been identified. CCS report high levels of psychological stress. Psychological stress activates the hypothalamic-pituitary-adrenal axis, which can disrupt reproductive function. The purpose of this exploratory study was to explore the relationship between perceived stress, biomarkers of hypothalamic-pituitary-adrenal activity, gonadotropin levels, and anti-Müllerian hormone levels in female CCS. This exploratory cross-sectional study included female cancer survivors (ages 16-35) treated for pediatric cancer at the Royal Hospital for Sick …
Compressed Sensing For Few-View Multi-Pinhole Spect With Applications To Preclinical Imaging, Benjamin Michael Rizzo
Compressed Sensing For Few-View Multi-Pinhole Spect With Applications To Preclinical Imaging, Benjamin Michael Rizzo
Dissertations (1934 -)
Single Photon Emission Computed Tomography (SPECT) can be used to identify and quantify changes in molecular and cellular targets involved in disease. A radiopharmaceutical that targets a specific metabolic function is administered to a subject and planar projections are formed by imaging emissions at different view angles around the subject. The reconstruction task is to determine the distribution of radioactivity within the subject from the projections. We present a reconstruction approach that utilizes only a few view angles, resulting in a highly underdetermined system, which could be used for dynamic imaging applications designed to quantify physiologic processes altered with disease. …
United States Born Mexican Origin Women's Descriptions About Their Eating Patterns, Juanita Teresa Garcia
United States Born Mexican Origin Women's Descriptions About Their Eating Patterns, Juanita Teresa Garcia
Dissertations (1934 -)
Problem. Mexican origin (MO) women comprise the largest Hispanic subgroup (nearly two-thirds) of Latinas in the US. This subgroup has high incidences of obesity and associated chronic diseases. Modifiable risk factors for obesity and chronic diseases include unhealthy diets and eating patterns. Efforts to understand eating patterns of Hispanics have focused on primarily first-generation Hispanics. To date, limited research has been conducted to explore underlying factors that contribute to eating patterns of US born MO women living in the US. Method. The purpose of this qualitative exploratory-descriptive study, using a thematic analysis approach, was employed to explore 15 US born …