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Full-Text Articles in Medicine and Health Sciences
Axonal Blockage With Microscopic Magnetic Stimulation, Hui Ye
Axonal Blockage With Microscopic Magnetic Stimulation, Hui Ye
Biology: Faculty Publications and Other Works
Numerous neurological dysfunctions are characterized by undesirable nerve activity. By providing reversible nerve blockage, electric stimulation with an implanted electrode holds promise in the treatment of these conditions. However, there are several limitations to its application, including poor bio-compatibility and decreased efficacy during chronic implantation. A magnetic coil of miniature size can mitigate some of these problems, by coating it with biocompatible material for chronic implantation. However, it is unknown if miniature coils could be effective in axonal blockage and, if so, what the underlying mechanisms are. Here we demonstrate that a submillimeter magnetic coil can reversibly block action potentials …
Underfeeding Patients With Critical Illness: Making Sense Of Recent Data, Jacklyn C. Hook, Patricia M. Sheean
Underfeeding Patients With Critical Illness: Making Sense Of Recent Data, Jacklyn C. Hook, Patricia M. Sheean
Parkinson School of Health Sciences and Public Health
Nutrition support is recognized as an important component of care for patients with critical illness. Providing energy and protein at estimated requirements is thought to prevent or decrease the likelihood of disease-related malnutrition. However, short-term calorie restriction may be advantageous in this setting. Using PubMed, we conducted a search for studies of “permissive underfeeding” or “hypocaloric feeding” for patients with critical illness to evaluate relevant outcomes. Of the initial 137 studies, 32 papers were evaluated, and 16 papers met all eligibility criteria. The results support a benefit or neutral impact on nutrition support-related complications, yet conflicting findings on mortality and …