Medicine and Health Sciences Commons^™

Effects Of Electrical Stimulation And Testosterone In Translational Models Of Peripheral Nerve Injury, Gina Monaco

Dissertations

As functional recovery following peripheral nerve injury is dependent upon successful regeneration and target reconnection, combinatorial treatments that enhance different regeneration events may be required for recovery from severe injuries. The neurotherapeutic effects of electrical stimulation (ES) and gonadal steroids have been demonstrated independently and in combination in extratemporal and intratemporal facial nerve injuries. The goals of the first aim were to develop a reliable intracranial facial nerve crush model and to investigate the therapeutic potential of combining ES with testosterone propionate (TP) in this most proximal injury model. Adult male rats were divided into intracranial sham-operated, intracranial crush, and …

Binge Alcohol And Recovery After Traumatic Brain Injury, Ian Vaagenes

Dissertations

An estimated 275,000 Americans are hospitalized following a traumatic brain injury (TBI) every year, 80,000 of whom develop a long-term disability. The factor that places one at perhaps the greatest risk of suffering a TBI is alcohol intoxication. 30-50% of TBI sufferers have a blood alcohol level above .08 mg/dl at the time of injury, the legal limit in most U.S. states. In fact, the presence of alcohol at the time of TBI more than doubles the risk of a repeat head injury in the two years following the injury. Given the large population of TBI sufferers with alcohol intoxication …

Emergency Nurses' Knowledge, Attitudes And Preventive Practices Regarding Firearms And Firearm Injury Prevention For Children, Dorothy Ann Gomez

Dissertations

In 2010, there were 134 deaths attributed to unintentional firearm injuries of children under 19 year and 3,019 nonfatal injuries (CDC, 2011). Nurses are expected to identify potential dangers in the community and protect those at risk. It was found that there is limited research on the effectiveness of current firearm injury prevention practices of nurses. The study was designed to examine the knowledge, attitudes and practice characteristics of Emergency Nurses toward firearm prevention practices. A convenience sample of 189 emergency nurses completed a voluntary, anonymous survey on practices regarding childhood gun safety. Seventy-one percent of respondents agreed that firearm …

Synthesis And Assembly Of Dihydroindolizines On Gold Surfaces For Light Induced Work Function Alterations, Matthew Alan Bartucci

Dissertations

Taking advantage of surfaces' response to interfacial dipoles, a class of photochromophores (dihydroindolizine) is demonstrated to alter the work function of the underlying substrate (170 meV). This same molecule also provides spectroscopic signatures for correlating the change in molecular structure to the induced change in the surfaces' electronic properties. Polarization modulation infrared reflection absorption spectroscopy (PM-IRRAS) allows analysis of the characteristic dihydroindolizine C=C (1559 cm-1) and pyridinium (1643 cm-1) stretch as a function of photoexcitation. Structural assignments of this photochromophore are corroborated to density function theory calculations. Conformational changes in the monolayers appear in parallel with work function changes and …

Risk Perception In Cardiovascular Disease, Michelle Ellen Block

Dissertations

Cardiovascular disease (CVD) remains among the leading causes of death in the United States despite widespread knowledge about risk factors as well as effective primary prevention strategies. Risk perception is a complex phenomenon that plays an important role in how persons view disease and ultimately how they make health behavior choices. This study is supported by the knowledge that few studies have examined how persons perceive cardiovascular risk or the variables thought to contribute to the formation of risk perception.

Purpose: The purpose of this study was to examine how accurately persons perceive personal risk for cardiovascular disease and identify …

Influence Of Pramipexole On Probability Discounting And Ventral Pallidal Function: Assessments In Parkinsonian-Like Rats, Sandra Lynn Rokosik-Kletzel

Dissertations

People with neuropathologies who are treated with dopamine agonists may be at risk to develop impulse control disorders. The overall goal of this dissertation project was to expand our knowledge on the neuropsychopharmacology of dopamine agonist-induced impulsivity. At the time this dissertation was being developed, pramipexole was the drug, gambling was the behavior, and Parkinson's disease (PD) was the pathology most widely reported for this phenomenon. Therefore, we first developed a behavioral paradigm (i.e., probability discounting) to measure risk-taking, one aspect of gambling. Utilizing this paradigm, we determine if risk-taking was altered after acute and/or chronic pramipexole treatment. We incorporated …

Beyond Retention: Exploring Mental Health Benefits Of Living Learning Programs, Christopher Zaddach

Dissertations

The transition to a university setting can be a particularly challenging and stressful experience for a significant proportion of first-year students who may struggle to cope with dramatic changes in academic and social demands. Despite available resources and services, universities continue to report significant attrition rates and increases in severity and intensity of mental health issues among first-year students. Living learning communities (LLCs) have long been recognized as programming options with the ability to support students' academic and social adjustment. The current study aimed to expand the literature on LLCs by examining the possible mental health benefits of living learning …

Opening The Black Box: Understanding Adult Inpatient Falls, Laura M. Rogers

Dissertations

Within the United States, falls are the largest category of adverse events reported in hospitals. Injuries associated with falls include increased costs, extended length of stays, increased mortality and morbidity, and liability to hospitals. The purpose of this study was to discover, describe, and systematically analyze universal and diverse care meanings and expressions of adults experiencing a fall while hospitalized. The research was conceptualized with the ethnographic theoretical framework of Culture Care Diversity and Universality (Leininger 2001, 2006). Data collection took place in a large academic medical center, over a five month period and included 24 participants: eight adult inpatients …