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Normative Data For Neurodiagnostic Auditory Brainstem Response Testing (Abr), David Alan Ness

Doctoral Dissertations

Auditory Brainstem Response (ABR) tests are procedures routinely performed to assess auditory function from the peripheral auditory system to the level of the lower brainstem. The ABR is used as a neurodiagnostic tool to detect retrocochlear pathologies of the auditory system, such as space occupying lesions, tumors, auditory neuropathy, and multiple sclerosis that effect the structures located above the level of the cochlea.

An ABR consists of eliciting and recording waveforms. These waveform recordings elicited are compared to normative data to determine normal versus abnormal (retrocochlear lesion) responses. Generalized normative data is available for ABR test results; however, research states …

Nano-Formulation And Controlled Delivery Of Low Solubility Anticancer Drugs, Anshul Agarwal

Doctoral Dissertations

Optimal drug delivery and reduction of systemic adverse effects have been age old problems in chemotherapeutics in all types of human cancer. During chemotherapy, using water insoluble drugs like paclitaxel and tamoxifen, it has been realized that better formulations are needed for more specific and controlled drug delivery of these agents. In a novel approach to form high content stable nanocolloids of these drugs with controllable release rate, a sonicated layer-by-layer (LbL) polyelectrolyte coating technology is suggested. The desired features of pharmaceutical carriers for intravenous administration include their small size and biodegradability, good loading capacity for a given drug, high …

Sound Pressure Levels Within The Ear Canal Of Ipod Users, Lawrence E. Bridge

Doctoral Dissertations

Portable listening devices, specifically iPods are becoming more and more popular among teens and young adults. According to Apple's quarterly financial results in March 2008, total iPod sales reached close to 152,000,000 since their release in January 2001 (Apple, 2008). Because nearly 15 million individuals suffer from noise induced hearing loss, listening levels of individuals using iPods are of main concern to audiologists. The purpose of this dissertation is to determine (1) average listening levels of males and females, as well as experienced and inexperienced iPod users and (2) if a certain groups of individuals are at more of a …