Medicine and Health Sciences Commons^™

Mechanisms By Which Exercise Training Attenuates Blood Pressure In Animals: Roles Of Cytokines, Oxidative Stress, And Glycogen Synthase Kinase-3Â, Deepmala Agarwal

LSU Doctoral Dissertations

Hypertension is a chronic multifactorial condition with high morbidity and mortality rates, currently affecting about one billion people worldwide. Currently available anti-hypertensive medications are found to be effective in reducing blood pressure (BP), but still more than 50% of those diagnosed with hypertension fail to respond to these anti-hypertensive regimens. Although hypertension has multiple etiologies, physical inactivity has been found to have strong correlation with the disease, so exercise has recently been recommended as a part of lifestyle modifications for all hypertensive patients. Therefore, the present series of in vivo and in vitro studies were undertaken to gain more insight …