Medicine and Health Sciences Commons^™

Fetal Whole-Body Fluid, Cardiovascular And Endocrine Dynamics : Computer Analysis Of Regulatory Mechanisms, Peter Stuart Gold

Loma Linda University Electronic Theses, Dissertations & Projects

The dynamics of transcapillary fluid and protein distribution and endocrine regulation of cardiovascular function were studied in chronically instrumented fetal sheep during the third trimester. Average experimental changes in vascular pressures, blood volume, plasma hormone concentrations, hematocrit and plasma protein concentration were analyzed using mathematical modeling and parameter optimization techniques in order to determine values for the major parameters which regulate fluid, protein and endocrine dynamics and to determine endocrine dose-response relationships to changes in cardiovascular function. The hormones which were considered are arginine vasopressin (AVP), angiotensin II (AII), epinephrine (EPI) and norepinephrine (NE). Vascular disturbances which were considered include …

Pre-Orthodontic Radiography Of The Temporomandibular Joint, Stephen G. Tracey

Loma Linda University Electronic Theses, Dissertations & Projects

The dental profession has given increased attention to temporomandibular joint problems in recent years. Many orthodontists have shown professional concern by taking pretreatment lateral tomograms to assess developmental abnormalities, previous injury, pathology, and condylar position. The purpose of this study was to determine the consistency of orthodontists in evaluating lateral tomograms and panoramic films, particularly when used prior to treatment. Lateral tomograms and panoramic films of 60 single joints were evaluated by 4 orthodontists on two separate occasions. A questionnaire was completed for each radiograph observed and responses were compared for interobserver and intraobserver [aggreement]. Statistically, results showed little to …

Update - October 1986, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Center presents faith and peace conference
-- Senator Gore addresses transplant ethics at LLU November 17
-- AAW features "Women of Courage" November 28-30
-- Is God "Dead" in Biomedical Ethics? (Critique)

[ Why Does God Let Us Suffer? ]
-- The Mystery of Suffering
-- Will Suffering Ever Really End?
-- Religion and Suffering Among My Patients
-- God and Suffering: A Discussion

Commencement Program 1986 (Summer Conferring Of Degrees), Loma Linda University

Commencement Programs

CONTENTS

3 |The Academic Procession

4 | Conferring of Degrees

6 | Candidates for Degrees

14 | Awards

Early Identification Of Risk For Noncompliance In Tuberculosis Patients, Penny Klein Weismuller

Loma Linda University Electronic Theses, Dissertations & Projects

In this descriptive study of early identification of risk for noncompliance to tuberculosis treatment or prevention regimens, 523 patients, from four ethnic groups, were rated by nurses trained as participant-observers of several predictive factors. The predictive factors included acceptance of diagnosis. attentiveness, eye contact, the treatment's interference with the patient's lifestyle, fear of side effects, fear of needed medical procedures, and the presence and degree of the patient's social support. An observational measure by the nurse of the patient's Health Locus of Control was also included. The patient was asked to provide a self-rating on the degree of difficulty anticipated …

The Effect Of Dietary Fat Level On Tumor Development And Immunity In Balb/C Mice Fed Casein Of Wheat Gluten As Protein And Challenged With Herpes Type 2-Transformed Cells, Helen Drakou

Loma Linda University Electronic Theses, Dissertations & Projects

A high percentage of fat in the diet has been implicated through epidemiological studies in several human cancers. Studies in experimental animals have produced evidence that increasing the fat in the diet decreases the animal’s ability to restrict tumor development and growth. In previous work done in this laboratory with BALB/c mice injected with herpes simplex Type 2-transformed mouse cells (H238), the effects of a diet which greatly enhanced tumor growth was compared with one which restricted tumor growth. The latter, a low (5%) fat, low protein diet, in which the protein was casein, was also found to produce a …

Relationship Between Dietary Intake And Reproductive Hormones In Premenopausal Vegetarian And Nonvegetarian Seventh-Day Adventist Women, Joan M. Spuehler

Loma Linda University Electronic Theses, Dissertations & Projects

There is evidence that specific nutrients may modify hormonal balance and contribute to breast cancer etiology. To investigate the relationship between dietary nutrients and plasma reproductive hormones and to determine hormone-nutrient interrelationships, we measured plasma estrogens, androgens. progesterone and prolactin levels in 10 premenopausal Seventh-day Adventist (SDA) vegetarian and 10 premenopausal SDA nonvegetarian women. Over three days in each of three consecutive months. diet records and fasting midluteal blood samples were collected. The nonvegetarians consumed significantly more protein, total and saturated fats, oleic and linoleic acids, and cholesterol than did the vegetarians. Hormonal status of the two groups did not …

Sprague-Dawley Rats Fed Milk Or Beef Protein : Differences In Response To 1,2-Dimethylhydrazine Carcinogenesis, Stanley W. L. Ng

Loma Linda University Electronic Theses, Dissertations & Projects

Colon cancer is responsible for a high percentage of cancer deaths in developing countries, and there is convincing epidemiological evidence that meat protein and fat in the diet increase the incidence of this form of cancer. An animal tumor model which has been used by many investigators interested in colon cancer is the 1,2-dimethylhydrazine (DMH)-rat or DMH-mouse tumor model. In previous work done in this laboratory the DMH-BALB/c mouse tumor model was used to compare the production of colon tumors in mice fed a diet using non-fat powdered milk as a source of protein with those in mice fed beef …

The Effects Of Certain Oral Bacteria On The In Vitro Growth Of Bacteroides Gingivalis, Steven G. Morrow

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of nine gram positive and grain negative cocci and bacilli, which are indigenous to the oral cavity, on the in vitro growth of Bacteroides gingivalis was examined in this study. A pure culture of B. gingivalis is was obtained from the American Type Culture Collection. The nine oral test organisms were Streptococcus mitis, Streptococcus mutans, Streptococcus faecalis, Staphylococcus epidermidis, Staphylococcus aureus, Corynebacteriurn hofmanii, Lactobacillus acidophilus, Branhamella catarrhalis, and Escherichia coli. The effect on the growth of B. gingivalis of the nine test organisms was evaluated on a solid medium by use of …

Effects Of A Structured Pretransfer Teaching Protocol On The Reduction Of Transfer Stress In Clients With Myocardial Infarction, Maureen R. Brennan Westphal

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

The Use Of Dura Mater As A Meniscus Replacement In Tmj Surgery, Kim J. Dipasquale

Loma Linda University Electronic Theses, Dissertations & Projects

Internal derangement of the temporomandibular joint is recognized as a problem of significant magnitude in both medical and dental circles. The last decade has seen a steady progression in the knowledge and sophistication of not only the anatomy and physiology of the temporomandibular joint, but also in the techniques of non-surgical and surgical management of internal derangements. Surgical correction of the unrepairable disc has typically been addressed by performing a menisectomy followed by placement of a non-physiologic implant material.

The animal study reported here was performed in order to evaluate the histologic fate and biological compatibility of freeze-dried dura when …

Language Disabilities Of Delinquent Adolescents, Sue E. Eaton

Loma Linda University Electronic Theses, Dissertations & Projects

Many studies have been conducted on the prevalence of learning disabilities in the population of juvenile delinquents (Holte, 1972; Broder, Dunivant, Smith, and Sutton, 1981; Meltzer, 1983; Bachara and Zada, 1978). One investigation conducted by the United States Government, found that juvenile delinquents have severe learning problems (Reed and Heilman, 1981).

Learning disabilities appear in eight to 10 percent of all school age children and adolescents. Of that group, 39 to 63 percent show a language disorder syndrome which may negatively affect school learning over a broad range of the curriculum area (Semel and Wiig, 1980). The prevalence of learning …

A Semiquantitative Analysis Of The Chorda Tympani Taste Pathway In The Rat Brain With The 2-Deoxyglucose Method, Charles L. Hardison

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis is based on a semiquantitative analysis of four nuclear relay centers [nucleus tractus solitarius (NTS), parabrachial nucleus (PBN), ventroposteromedial nucleus (VPM), gustatory neocortex (GNC)] in the chorda tympani nerve pathway. Metabolic changes were examined by the 2-deoxyglucose method in which one chorda tympani nerve was chemically stimulated and its contralateral side lesioned. Coronal sections of four taste centers were prepared for autoradiography and Nissl staining. Densities of the autoradiograms were determined by means of a video based image processor. Relative differences in the optical density ratios of the stimulated versus lesioned nuclear grey matter areas to white matter …

Update - July 1986, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Baby Jessie and Beyond
-- Newsbriefs
-- The Bouvia Decision: Right But Inadequate
-- LLU plans conference on ethics and transplantation

[ Apartheid and Morality Today ]
-- Growing Up White in South Africa
-- In Favor of Constructive Engagement
-- Divestment: Realistic Moral Opposition to Apartheid

-- What should treatment committees consider?
-- Religion and Politics on Sabbath (Editorial)
-- George Otto Schumacher, MD (1913-1986)
-- Thomas Gordon Goman, PhD (1944-1986)

Commencement Program 1986, Loma Linda University

Commencement Programs

CONTENTS

2 | 1986 Events of Commencement

3 | Academic Procession

7 | The Honorees

Order of Program

• School of Medicine, 12
• Graduate School, 18
• School of Dentistry, 23
• School of Nursing, 29
• College of Arts and Sciences and Education, 33
• School of Allied Health Professions, 44
• School of Health, 49

Effects Of Lateral Mandibular Expansion On Mandibular Morphology In The Growing Rat : A Comparative Study Of Treatment Effects With Orthopaedic And/Or Surgical Procedures, Eric Looi

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to investigate the effects of mandibular expansion by orthopaedic and surgical procedures in the growing rat mandible.

Sixty-four 35 day old Sprague Dawley Harlan rats were divided into four groups of 16 rats each and categorized as the control, orthopaedic expansion, surgery without graft and surgery with graft respectively. Prefabricated appliances were used for orthopaedic expansion of the mandibles and maintaining surgical expansion at the symphysis in the respective groups. Oxytetracycline were given intraperitoneally to mark areas of bone remodeling. Half the number of rats from each group were sacrificed at the end of …

The Relationship Between Meat Consumption And The Biological Determinants Of Cardiovascular Disease Risk, Fred E. Kollwitz

Loma Linda University Electronic Theses, Dissertations & Projects

Fasting blood samples were collected from 26 omnivore and 27 vegetarian men (35-60 years of age), who were not taking any medications and by self-assessment were in good health. The following analyses were done: glucose (Glu), glycohemoglobin (HBA1), total serum cholesterol (chole), high density lipoprotein-cholesterol (HDD, low density lipoprotein (LDL), very low density lipoprotein (VLDL), platelet factor four (PF4), and beta-thromboglobulin (BTG). In addition, the blood pressure (BP) was determined.

The systolic (p<0.001) and diastolic BP (p=0.016) were lower in the vegetarian subjects than in the omnivores. The serum total cholesterol levels were also lower in the vegetarian subjects compared to the omnivores (p<0.05). There was no significant difference in Glu, HBA1, LDL, VLDL, HDL, PF4, and BTG levels between the two groups.

Corticotomy Facilitated Orthodontic Treatment In Adults : A Report Of Two Cases, Randall E. Hoff

Loma Linda University Electronic Theses, Dissertations & Projects

The corticotomy procedure is a surgical technique that has been used to facilitate orthodontic treatment for many years. Proponents of this technique contend that occlusal results are more stable and treatment time is reduced. In this study, two cases of dento-alveolar abnormality are presented that were successfully treated in a relatively short time by using the combined efforts of the surgeon and the orthodontist. Although corticotomy has limited applications, it has a place in the armamentarium of the modern orthodontist.

Key Words: Corticotomy, Adult Orthodontics, Osteotomy.

An Immunochemical Analysis Of Alcoholic Hyaline And Its Relationship To Keratin Intermediate Filaments, David L. Drexler

Loma Linda University Electronic Theses, Dissertations & Projects

Alcoholic Hyaline (AH) and keratin intermediate filaments possess ultrastructural, biochemical and immunochemical similarities. This study compares human AH, human stratum corneum keratin (HSCK) and normal human liver cytokeratin (HCK) by quantitative immunochemical means, using polyclonal as well as monoclonal antibodies. Enzyme-linked immunosorbent assays (ELISAs) were employed, as well as "immunoblotting" and immunocytochemical techniques. HCK was isolated using Triton X-100 and "high-salt” buffers and exhibited seven major polypeptide bands on SDS-PAGE (41-58 kd). Antisera were made toward HCK and the two major HCK bands. Other immunochemicals included antisera toward AH, the three major AH bands, and HSCK, as well as 3 …

Interaction Of Putative Estrogens And The Estrogen Receptor System In Leydig Cells In The Balb/C Mouse Testis Resulting In The Initiation Of Dna Synthesis, R. Lloyd Juriansz

Loma Linda University Electronic Theses, Dissertations & Projects

Continuous administration of estrogens for 7-9 months, both steroidal and nonsteroidal, to male BALB/c mice, leads to the formation of testicular Leydig cell tumors. Three days following the subcutaneous implantation of a pellet of estrogen in cholesterol, there is a peak in the incorporation of ³H-tymidine into the DNA of the interstitial cells. These effects are hypothesized to be mediated by the estrogen receptor system in the Leydig cell. Common experimental techniques for the measurement of hormone binding, such as dextran coated charcoal treatment, proved to be impossible to employ in this system, therefore a procedure was developed using …

Axial Morphology And Angulation Of The Condyle In Relation To Malocclusions In Different Age Groups, Gerald P. Tadej

Loma Linda University Electronic Theses, Dissertations & Projects

Recent studies have shown that forces applied to the mandible during functional appliance and other orthodontic therapies produce measurable changes in the TMJ. It was postulated that specific malocclusions might also apply forces that could produce specific changes in the horizontal morphology of the TMJ. This study involved 104 pretreatment orthodontic patients, 44 males and 60 females. A submento-vertex analysis was performed and correlated with clinical findings including age, sex, malocclusion type, facial type, TMJ symptoms, tooth eruption sequence, crossbites and midline discrepancies. All possible correlations between the radiographic findings and the clinical malocclusions were tested with ANOVA. The width …

Quick Ceph™, A Computer Program For Cephalometric Analysis And Treatment Planning, Günther Blaseio

Loma Linda University Electronic Theses, Dissertations & Projects

The quantification of cephalometric radiographs is an integral part of orthodontic treatment planning. Numerous computer programs have been designed to digitize headfilms and to provide accurate graphic output and exact measurements. Yet these early systems were either huge, bulky and expensive or were limited in their practical use. The aim of this development was to combine modern computer and electronic equipment with advanced software engineering. The result is a universal cephalometric program written in the computer language "C" with presently seven standard and virtually limitless user definable analyses, growth forecasting, mouse-driven interactive VTO, arch length calculation, superimpositions, table of values …

Association Of Drinking-Related Locus Of Control And Treatment Outcomes In Female Alcoholics, Patricia A. Townsend

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

Correlates Of Birth Weight And Gestation Age : Baseline Data For Health Education, Adanetch Kidanemariam

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose. The study examined the correlation of maternal occupation, urinary tract infection, smoking, and working during pregnancy with infant birth weight and gestational age in order to generate baseline data for development of a health education intervention program protocol for pregnant women In the work place.

Primary Hypotheses. (1) The four maternal risk factors: (a) occupation during lifetime, (b) reported urinary tract infection, (c) cigarette smoking, (d) working, are individually and interactively correlated with infant birth weight and gestational age. (2) The effects of the interactive associations are greater on birth weight than gestational age.

Procedure. A sample of …

Amount Of Root Shortening Related To Type Of Fixed Appliance : A Comparison Of The 0.018" And 0.022" Bracket Slot, Thomas L. Thompson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine if a different incidence and severity of maxillary incisor apical root resorption occurs in cases treated with the 0.018 inch versus 0.022 inch slot in standard edgewise mechanics. A consecutively treated sample of 240 patients (98 boys and 142 girls), with a mean age of 13.4 years from the orthodontic clinic at Loma Linda University were studied. 120 of the cases were treated using 0.018" bracket slot with standard edgewise mechanics and 120 were treated using 0.022" non-torqued full banded standard edgewise mechanics. 60 of the cases in each of the above …

Update - March 1986, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Endowment effort succeeds!
-- In honor of my father
-- Are Apartheid and Nuclear War Biotheical Issues? (Editorial)

[ ABORTION: Understanding Our Differences ]
-- Excerpts from a husband and wife 'debate' regarding abortion

-- The Ethics of Biomedical Ethicists (Critique)

The Effect Of Social Support Upon Compliance As Measured By Functional Health Patterns, Olivia Catolico-Dixon

Loma Linda University Electronic Theses, Dissertations & Projects

Observation of client noncompliance with therapeutic regimens prompted this study. The purpose of this study was to investigate the client's social support system and its effect on compliance. The null hypothesis constructed was:

H₀: There will be no relationship between social support and compliance as measured by functional health patterns in the Chronic Obstructive Pulmonary Disease Client (COPD) ( cx = 0.05).

A convenience sample of 38 subjects from the outpatient Pulmonary Clinic at a Southern California Veterans' Administration Hospital were interviewed for this study. Using a structured interview format, the investigator administered four questionnaire tools to each …

Update - January 1986, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Symposia discuss abortion, apartheid, and nuclear war
-- Endowment effort faces January deadline
-- Center prepares first book
-- Religion and the Bioethical Enterprise (Editorial)
-- Letter to the Editor

[ What's A Little Church Like Ours Doing in Big Medicine Like This? ]
-- Excepts from public discussion
-- From Water Cures to ORgan Transplants: Have We Lost Our Way?
-- Healing the Sick and Preaching the Gospel: Is There An Essential Link?
-- Adventist Institutions and the World: If Small Is Beautiful, Is Big Bad?
-- The Adventist Health System: Are We Drifting …