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Sustained Medication Reduction Following Unilateral Vim Thalamic Stimulation For Essential Tremor, Andrew S. Resnick, Michael S. Okun, Teresita Malapira, Donald A. Smith, Fernando L. Vale, Kelly L. Sullivan, Amber M. Miller, Israt Jahan, Theresa A. Zesiewicz
Sustained Medication Reduction Following Unilateral Vim Thalamic Stimulation For Essential Tremor, Andrew S. Resnick, Michael S. Okun, Teresita Malapira, Donald A. Smith, Fernando L. Vale, Kelly L. Sullivan, Amber M. Miller, Israt Jahan, Theresa A. Zesiewicz
Kelly L. Sullivan
Background: Deep brain stimulation (DBS) is an increasingly utilized therapeutic modality for the management of medication refractory essential tremor (ET). The aim of this study was to determine whether DBS allowed for anti-tremor medication reduction within the year after the procedure was performed.
Methods: We conducted a retrospective chart review and telephone interviews on 34 consecutive patients who had been diagnosed with ET, and who had undergone unilateral DBS surgery.
Results: Of the 34 patients in our cohort, 31 patients (91%) completely stopped all anti-tremor medications either before surgery (21 patients, 62%) or in the year following DBS surgery (10 …
Overview Of The Essential Tremor, Theresa A. Zesiewicz, Abinaya Chari, Israt Jahan, Amber M. Miller, Kelly L. Sullivan
Overview Of The Essential Tremor, Theresa A. Zesiewicz, Abinaya Chari, Israt Jahan, Amber M. Miller, Kelly L. Sullivan
Kelly L. Sullivan
Essential tremor (ET) is one of the most common movement disorders in the world. Despite this, only one medication (propranolol) is approved by the Food and Drug Administration (FDA) to treat it. Fortunately, recent studies have identified some additional medications as treatment of ET. Surgical procedures, such as deep brain stimulation of the ventral intermediate nucleus of the thalamus, offer treatment for refractory tremor. The epidemiology, pathogenesis, and medical and surgical treatment of ET will be discussed in this paper.