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Full-Text Articles in Medicine and Health Sciences
The Effect Of Omega-3 As Diet-Enhanced Immunity On Sepsis Outcome In Critically Ill Patients, A Abd El Rhaman, Hatem A. Attallah, Marwa M. Taha, Wesam E. Salutan
The Effect Of Omega-3 As Diet-Enhanced Immunity On Sepsis Outcome In Critically Ill Patients, A Abd El Rhaman, Hatem A. Attallah, Marwa M. Taha, Wesam E. Salutan
Menoufia Medical Journal
Background Nutritional supplementation of omega-3 fatty acids has been proposed to modulate the balance of proinflammatory and anti-inflammatory mediators in sepsis and acute lung injury. Objectives To evaluate the effect of omega-3 fatty acids as diet-enhanced immunity on sepsis outcome in critically ill patients. Patients and methods Sixty patients with early sepsis were divided equally into two groups: group A who received high-dose omega-3 fatty acids for consecutive 7 days besides conventional sepsis treatment, group B: control group who received only conventional sepsis treatment. Both groups were followed up by inflammatory markers, sequential organ failure assessment score monitoring, need for …
8-Hydroxy-2-Deoxyguanosine As A New Biomarker Of Oxidative Stress In Patients With Acne Vulgaris, Eman F. Abd Elfadil Albarqi, Magda M. Hagag, Nesreen G. Elhelbawy
8-Hydroxy-2-Deoxyguanosine As A New Biomarker Of Oxidative Stress In Patients With Acne Vulgaris, Eman F. Abd Elfadil Albarqi, Magda M. Hagag, Nesreen G. Elhelbawy
Menoufia Medical Journal
Objectives To evaluate the serum level of 8-hydroxy-2-deoxyguanosine (8-OHdG) in patients with acne vulgaris and also to detect relation between serum level of 8-OHdG and acne vulgaris severity. Background Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles, characterized mainly by comedones. The precise mechanisms of acne are not known. Oxidative stress within the pilosebaceous unit are considered an important initiating step in the pathogenesis of acne. 8-OHdG is considered to be one of the main biomarkers of oxidative stress. Patients and methods This cross-sectional study was carried out on 75 patients with mild, moderate, and severe acne …
Neutrophils-To-Lymphocyte Ratio In Acute Ischemic Stroke Patients, Eman S. Matar, Gelan M. M. Ali, Ibrahim E. Alahmar, Wafeek M. Elsheik
Neutrophils-To-Lymphocyte Ratio In Acute Ischemic Stroke Patients, Eman S. Matar, Gelan M. M. Ali, Ibrahim E. Alahmar, Wafeek M. Elsheik
Menoufia Medical Journal
Objective The aim of this study was to evaluate the neutrophils-to-lymphocyte ratio (NLR) among patients with ischemic stroke and to determine the relationship between NLR and poststroke prognosis Background Inflammations play a role in the pathogenesis of cerebral infarction. Cytokines and adhesion molecules regulate the increased migration of leukocytes to the brain. Neutrophils are the first type of leukocytes to infiltrate ischemic brain (30 min of cerebral ischemia), peak earlier (days 1–3), and then decrease rapidly with time. Lymphocyte recruitment into the brain is involved in the later stages of ischemic brain injury. Patients and methods A retrospective study was …
Mean Platelet Volume As A Diagnostic Marker In Children With Acute Hepatitis A, Amany F. Ismael, Maha A. Tawfik, Soheir S. Abou El-Ella
Mean Platelet Volume As A Diagnostic Marker In Children With Acute Hepatitis A, Amany F. Ismael, Maha A. Tawfik, Soheir S. Abou El-Ella
Menoufia Medical Journal
Objective The aim of this study was to assess the level of mean platelet volume (MPV) in children with acute hepatitis A as compared with the control group. Background MPV is a marker that indicates platelet size, function, and the rate of platelet production and activation. Patients and methods Our study was conducted on 100 Egyptian children, aged from 2 to 14 years (58 male and 42 female) previously diagnosed as having hepatitis A as a patient group and 100 apparently healthy age-matched and sex-matched children as a control group. All of them were subjected to full history, physical examination, …
Study Of Serum Ykl-40 Level In Patients With Chronic Obstructive Pulmonary Disease, Ahmed A. Khames, Doaa S. Fouda, Ibrahim S. El Madbouh, Maha Yousif, Nourane Y. Azab
Study Of Serum Ykl-40 Level In Patients With Chronic Obstructive Pulmonary Disease, Ahmed A. Khames, Doaa S. Fouda, Ibrahim S. El Madbouh, Maha Yousif, Nourane Y. Azab
Menoufia Medical Journal
Objective The aim of the paper was to investigate the relationship between serum YKL-40 levels and severity of chronic obstructive pulmonary disease (COPD). Background COPD is a major health problem with increasing morbidity and mortality throughout the world. A newly recognized biomarker, YKL-40, is a chitin-binding glycoprotein, and its serum level is elevated in inflammatory diseases. However, it has not been thoroughly investigated in COPD. Patients and methods A total of 30 patients with stable COPD and 10 healthy individuals as a control group were enrolled for estimation of modified Medical Research Counseling dyspnea scale, spirometry, and serum YKL-40 levels. …
Effect Of Methylprednisolone On Inflammatory Markers And Patients' Outcomes In Acute Respiratory Distress Syndrome, Ahmad A. Metwally, Elham M. El-Feky, Mohammad E. S. Saleh, Waleed M. Fathy
Effect Of Methylprednisolone On Inflammatory Markers And Patients' Outcomes In Acute Respiratory Distress Syndrome, Ahmad A. Metwally, Elham M. El-Feky, Mohammad E. S. Saleh, Waleed M. Fathy
Menoufia Medical Journal
Objective The aim of this study wa s to evaluate the effect of methylprednisolone on inflammatory markers including C-reactive protein and interleukin-6 (IL-6) in acute respiratory distress syndrome (ARDS) at an early stage and on patients' outcomes. Background ARDS is started by an inflammatory injury to the lung that results in severe gas exchange impairment and lung compliance abnormalities. Increased levels of bronchoalveolar lavage and blood level of inflammatory biomarkers at ARDS onset are associated with worst prognosis that persists for no less than 7 days. Believing the way that inflammation is the main pathophysiology of ARDS, steroids would be …
Correlation Between Serum Triiodothyronine Level And Inflammation In Hemodialysis Patients, Alaa E. Abdel-Salam Dawood, Eslam M. Abdelwahab Elshewy, Mostafa M. Elnagar
Correlation Between Serum Triiodothyronine Level And Inflammation In Hemodialysis Patients, Alaa E. Abdel-Salam Dawood, Eslam M. Abdelwahab Elshewy, Mostafa M. Elnagar
Menoufia Medical Journal
Objective The aim of this work was to study the correlation between serum free triiodothyronine (FT3) level and inflammation in hemodialysis (HD) patients. Background End-stage renal disease (ESRD) is associated with a markedly increased mortality risk, with cardiovascular diseases being the most common cause of death. FT3 is a marker of comorbidity in ESRD and in many acute and chronic diseases. Patients and methods This case–control study included 30 patients with ESRD on maintenance HD (17 men and 13 women) (mean age 43.93 ± 12.12 years), 20 patients with chronic kidney disease not on HD (12 male and eight female) …
The Correlation Between Residual Renal Function And Inflammation In Chronic Hemodialysis Patients, Ashraf A. Dawood, Elsayed G. Mahros, Khaled M. Amin El Zorkany, Said S. Ahmed Khamis, Yassin S. Yassin
The Correlation Between Residual Renal Function And Inflammation In Chronic Hemodialysis Patients, Ashraf A. Dawood, Elsayed G. Mahros, Khaled M. Amin El Zorkany, Said S. Ahmed Khamis, Yassin S. Yassin
Menoufia Medical Journal
Objective The aim of the study was to study any possible correlation between inflammation and residual renal function (RRF) in chronic hemodialysis (HD) patients. Background RRF plays an important role in maintaining fluid balance, phosphorus control, nutrition, and removal of middle molecular uremic toxins. Decline of RRF also contributes significantly to anemia, inflammation, and malnutrition in patients on dialysis. Inflammation and activation of acute-phase responses are common in chronic kidney disease patients. The causes of inflammation in HD patients are multifactorial. Inflammatory reaction may originate from several sources, including graft or fistula infections, bioincompatible dialysis membrane, dialysate, endotoxin exposure, back …
Effect Of Omega-3 Supplementation On Lipid Profile And Inflammatory Markers In Children On Chronic Hemodialysis, Ali M. Elshafie, Fathia M. Elnemr, Ghada M. Elmeshad, Mohamed A. Mohamed Elsayed, Mohammed H. Bahbah
Effect Of Omega-3 Supplementation On Lipid Profile And Inflammatory Markers In Children On Chronic Hemodialysis, Ali M. Elshafie, Fathia M. Elnemr, Ghada M. Elmeshad, Mohamed A. Mohamed Elsayed, Mohammed H. Bahbah
Menoufia Medical Journal
Objectives: The aim of this study was to evaluate the effect of omega-3 supplementation on the lipid profile and inflammatory markers in children on chronic hemodialysis. Background: Children with end-stage renal disease on hemodialysis are at a high risk of adverse cardiovascular events. Dyslipidemia is an important risk factor for cardiovascular morbidity and mortality in dialysis patients, Patients who are on hemodialysis have elevated serum levels of inflammatory markers. There is a growing interest in the application of omega-3 fatty acids in the prevention of cardiovascular disorders in dialysis patients. Omega-3 fatty acids have been postulated to reduce proinflammatory response, …