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Articles 1 - 30 of 195
Full-Text Articles in Medicine and Health Sciences
Pattern Of Coronary Artery Disease In High-Risk Patients Without Prior Myocardial Infraction, Abd Elmoaty G. Kishk, Hala M. Badran, Naglaa F. Ahamed
Pattern Of Coronary Artery Disease In High-Risk Patients Without Prior Myocardial Infraction, Abd Elmoaty G. Kishk, Hala M. Badran, Naglaa F. Ahamed
Menoufia Medical Journal
Objective This study aimed to assess the causes, risk factors, outcome, and recommendation of patients with coronary artery disease without prior obstruction. Materials and methods Medline databases (PubMed, Circulation, American Society of Echocardiography, Journal of American Colleague of Cardiology, and ScienceDirect) and also materials available on the internet. The search was performed in the electronic databases from 2012 to 2017. The initial search presented 60 articles of which 23 met the inclusion criteria. The articles studied the pattern of coronary artery disease in patients with risk factors without prior obstruction. If the studies did not fulfill the inclusion criteria, …
Clinical And Angiographic Predictors Of Success In Chronic Total Occlusion Coronary Angioplasty, Ahmad M. Mahmoud Elsheikh, Ahmed A E Emara, Ahmed M. Elkersh, Alaa-Eldeen A. Hataba
Clinical And Angiographic Predictors Of Success In Chronic Total Occlusion Coronary Angioplasty, Ahmad M. Mahmoud Elsheikh, Ahmed A E Emara, Ahmed M. Elkersh, Alaa-Eldeen A. Hataba
Menoufia Medical Journal
Objective The aim of this study was to define the preinterventional parameters for procedural success of chronic total occlusion (CTO) coronary angioplasty. Background CTOs are encountered in 15–30% of patients undergoing coronary angiography. Compared with failed CTO angioplasty, successful CTO angioplasty has been associated with improvement in angina and left ventricular function and increased survival. Compared with intervention of nonoccluded stenoses, the recanalization of CTOs requires expert operator skills, increased procedural time, and increased radiation exposure to the patient, physician, and catheterization laboratory staff. Materials and methods This prospective study was conducted from April 2014 to March 2015 in Kobry …
The Role Of Diffusion-Weighted Mri On The Differentiation Of Complex Adnexal Masses, El-Sayed M. El-Sayed, Hamed G. Ali, Mohmad S. Abdullah
The Role Of Diffusion-Weighted Mri On The Differentiation Of Complex Adnexal Masses, El-Sayed M. El-Sayed, Hamed G. Ali, Mohmad S. Abdullah
Menoufia Medical Journal
Background Conventional MRI has an established role in gynecologic imaging. However, increasing clinical demand for improved lesion characterization and disease mapping to optimize patient management has resulted in the incorporation of newer sequences, such as diffusion-weighted imaging (DWI), into routine protocols for pelvic MRI. DWI provides functional information on the microenvironment of water in tissues, hence augmenting the morphologic information derived from conventional MRIs. Objective The objective of this study was to highlight the role of DWI in differentiating benign from malignant complex adnexal masses. Patients and methods Twenty-five patients with adnexal masses underwent conventional MRI and DWI and the …
Decreased Expression Of Microrna-451 Is Associated With Imatinib Mesylate Resistance In Patients With Chronic Myeloid Leukemia, Amira M. F. Shehata, Khaled A. Khalifa, Omaima M. Abbas, Raafat M. Abdlfattah, Sally S. Mandour Esawy, Suzan A. El-Hassanein
Decreased Expression Of Microrna-451 Is Associated With Imatinib Mesylate Resistance In Patients With Chronic Myeloid Leukemia, Amira M. F. Shehata, Khaled A. Khalifa, Omaima M. Abbas, Raafat M. Abdlfattah, Sally S. Mandour Esawy, Suzan A. El-Hassanein
Menoufia Medical Journal
Objectives To measure the expression levels of microRNA-451 (miR-451) in patients with chronic myeloid leukemia (CML) and to correlate miR-451 expression levels with response to imatinib mesylate (IM)-based therapeutic protocol. Background miRNAs are regulatory RNAs that have been classified as crucial players of cancer initiation and progression. Recent studies have illustrated an association between certain hematological malignancies and dysregulated miRNAs expressions; other studies have focused on the utilization of miRNAs as molecular biomarkers of cancer detection, outcome, and response to therapy. Patients and methods Real-time quantitative PCR technique was used to estimate the plasma miR-451 expression levels of 10 newly …
Evaluation Of Serum Kisspeptin In Infertile Men With Severe Oligospermia, Abdalla M. Attia, Bilal A. El-Mohsen Montaser, Hossam A. El Hamid Yassien, Mohammed M. El-Meligi
Evaluation Of Serum Kisspeptin In Infertile Men With Severe Oligospermia, Abdalla M. Attia, Bilal A. El-Mohsen Montaser, Hossam A. El Hamid Yassien, Mohammed M. El-Meligi
Menoufia Medical Journal
Objective The aim of this study was to determine whether an abnormality in the serum levels of kisspeptin is associated with oligospermia and male infertility. Background The study of kisspeptin has yielded a new concept on the physiology of the hypothalamic–pituitary–testicular axis and thus the sexual and reproductive functions of men. Patients and methods Our case–control study included 44 male participants aged 20–45 years divided into two groups: a case group composed of 22 infertile men with severe oligospermia and with normal serum levels of testosterone, luteinizing hormone, follicle-stimulating hormone, and prolactin and an age-matched control group composed of 22 …
Effect Of Ursodeoxycholic Acid On Indirect Hyperbilirubinemia In Neonates Treated With Phototherapy, Eman El-Sayed Al Kafory, Fady M. El-Gendy, Wael A. Bahbah
Effect Of Ursodeoxycholic Acid On Indirect Hyperbilirubinemia In Neonates Treated With Phototherapy, Eman El-Sayed Al Kafory, Fady M. El-Gendy, Wael A. Bahbah
Menoufia Medical Journal
Objective The aim was to evaluate the role of ursodeoxycholic acid (UDCA) on neonatal indirect hyperbilirubinemia treated with phototherapy. Background Hyperbilirubinemia is a common neonatal problem. The present study aimed to investigate the role of UDCA on neonatal hyperbilirubinemia treated with phototherapy. Participants and methods This randomized controlled clinical trial was conducted on 100 full-term neonates with unconjugated hyperbilirubinemia, who received phototherapy in the neonatal ICU of Menoufia University Hospital, and they were randomly divided into two groups: group 1, which is the case group (n = 50), received ursofalk (250 mg capsule) in dose of 10 mg/kg/day divided …
Laparoscopic Cystic Duct Exploration, Ehab S. A. Mahmoud, Hatem M. Soltan, Mohammed S. Ammar, Mohammed A. El Balshy
Laparoscopic Cystic Duct Exploration, Ehab S. A. Mahmoud, Hatem M. Soltan, Mohammed S. Ammar, Mohammed A. El Balshy
Menoufia Medical Journal
Objective To evaluate the benefits of routine cystic duct exploration during laparoscopic cholecystectomy (LC). Background The era of LC has been established as it decreases postoperative pain, shortens the hospital stay, and returns the patient to full activity within 1 week. Cystic duct stones (CDS) especially in patients with multiple tiny gallbladder are implicated in postcholecystectomy pain, failure of insertion of transcystic intraoperative cholangiography catheter, and the subsequent development of common bile duct (CBD) stones. Patients and methods This was a prospective study that included 30 patients with chronic calcular cholecystitis with multiple tiny stones. The patients were operated at …
Nutrition In Critically Ill Pediatric Patients: A Systemic Review, Ali M. Elshafie, Dalia M. El-Lahony, Hanem R M Ghetas, Wael A. Bahbah, Zein A. Omar
Nutrition In Critically Ill Pediatric Patients: A Systemic Review, Ali M. Elshafie, Dalia M. El-Lahony, Hanem R M Ghetas, Wael A. Bahbah, Zein A. Omar
Menoufia Medical Journal
Objective The study aimed to review the different types of nutrition in critically ill pediatric patients. Data sources Medline databases (PubMed, Medscape, Science Direct, EMF-Portal, Google Scholar) and all materials available in the Internet from 2001 to 2014 were searched. Study selection The initial search presented 150 articles of which 50 met the inclusion criteria. The articles studied the role of nutritional management in critically ill pediatric patients. Data extraction If the studies did not fulfill the inclusion criteria, they were excluded. Study quality assessment included whether ethical approval was gained, eligibility criteria specified, adequate information provided, and assessment measures …
Left Ventricular Strain In Pediatric Patients With End-Stage Renal Disease, Ahmed A. Khattab, Fahima M. Hassan, Mahmoud A. Soliman, Marwa G S Feteih, Rania S. El-Zayat
Left Ventricular Strain In Pediatric Patients With End-Stage Renal Disease, Ahmed A. Khattab, Fahima M. Hassan, Mahmoud A. Soliman, Marwa G S Feteih, Rania S. El-Zayat
Menoufia Medical Journal
Objective To evaluate left ventricular function using speckle tracking echocardiography (STE) in pediatric patients with end-stage renal disease (ESRD) with preserved left ventricular ejection fraction. Background ESRD is considered a leading cause of cardiovascular morbidity and mortality in pediatric patients. With the help of newer echocardiographic modalities such as two-dimensional (2D) STE, an early diagnosis of the cardiac involvement through the detection of subclinical myocardial dysfunction might be possible in pediatric patients with ESRD. Patients and methods This study was carried out on 35 children under regular hemodialysis for at least 3 days weekly owing to ESRD who were followed …
Role Of Sonography As An Adjunct To Mammography In Women With Dense Breasts, Mohamed R. El Kholy, Nagwan R. Mishmisha, Waleed A. Mousa
Role Of Sonography As An Adjunct To Mammography In Women With Dense Breasts, Mohamed R. El Kholy, Nagwan R. Mishmisha, Waleed A. Mousa
Menoufia Medical Journal
Objective The aim was to evaluate breast lesions using mammography (MG) and ultrasonography (USG) independently and in combination in women with dense breasts. Background Women with dense breasts are at higher risk of developing breast cancer and at greater risk of cancer being not detected because of masking of the radiological signs of cancer by increased density. Therefore, multiple imaging modalities are required. USG is an imaging modality that can overcome limitations of MG and it is important for correct diagnosis. Materials and methods Our study was carried out on 100 female patients with dense breast lesions who attended Menouf …
Influence Of Secondary Hyperparathyroidism On Left Ventricular Function In Maintenance Hemodialysis Patients, Ahmad T. H. Abouseriwa, Hassan A. Ahmed, Khaled M. A. Elzorkany, Yassein S. Yassein
Influence Of Secondary Hyperparathyroidism On Left Ventricular Function In Maintenance Hemodialysis Patients, Ahmad T. H. Abouseriwa, Hassan A. Ahmed, Khaled M. A. Elzorkany, Yassein S. Yassein
Menoufia Medical Journal
Objective The aim of this work was to assess the influence of secondary hyperparathyroidism (SHPT) on left ventricular function in end-stage kidney disease in Egyptian patients under maintenance hemodialysis. Background SHPT is a common disorder in patients with chronic kidney disease. Parathyroid hormone (PTH) is a major uremic toxin and may be responsible for long-term consequences that include renal osteodystrophy, severe vascular calcifications, alterations in cardiovascular structure and function, immune dysfunction, and anemia. PTH has been identified as an important cardiotoxin in end-stage kidney disease and may cause deleterious effects in myocardium metabolism and function. Materials and methods A total …
Differentiation Of Umbilical Cord Wharton's Jelly Derived Mesenchymal Stem Cells Into Cardiomyocytes Using 5-Azacytidine, Gehad H. Shalby, Rasha I. Noureldin, Waled M. Fathy
Differentiation Of Umbilical Cord Wharton's Jelly Derived Mesenchymal Stem Cells Into Cardiomyocytes Using 5-Azacytidine, Gehad H. Shalby, Rasha I. Noureldin, Waled M. Fathy
Menoufia Medical Journal
Objectives The objective of this article was to differentiate mesenchymal stem cells (MSCs) into cardiomyocytes. Background Cardiomyopathies resulted in permanent loss of cardiomyocytes as it had no ability of regeneration. This made MSCs a promising tool for cellular therapy because of their ability of self-renewal and multipotency. MSCs were considered ideal for cellular cardiomyoplasty as they can undergo full cardiogenic differentiation. Now it was believed that isolated cells from umbilical cord and expanded in vitro were a potential source of MSCs. Patients and methods An experimental study included 10 pregnant females due for delivery between October 2015 and April 2017. …
Evaluation Of Urinary Vitamin D-Binding Protein In Type 1 Diabetic Children, Maha A. Tawfik, Mai A. El-Borai, Sally M. El-Hefnawy, Soheir S. Abou-El Ella
Evaluation Of Urinary Vitamin D-Binding Protein In Type 1 Diabetic Children, Maha A. Tawfik, Mai A. El-Borai, Sally M. El-Hefnawy, Soheir S. Abou-El Ella
Menoufia Medical Journal
Objective The aim of the study was to measure the levels of vitamin D-binding protein (VDBP) and microalbumin in the urine of diabetic children (type 1) and to analyze the correlation of VDBP with other parameters. Background Elevated urinary vitamin D-binding protein (UVDBP) level in patients with diabetes indicates that renal tubular damage may be involved in early stages of the development of diabetic nephropathy (DN). Patients and methods A total of 20 type 1 diabetic patients and 20 healthy controls were subjected to full history taken, thorough clinical examination, and laboratory investigation, which included complete blood count, blood glucose …
Cord Blood Albumin–Bilirubin As A Predictor For Neonatal Hyperbilirubinemia, Ghada M. El Mashad, Hanan M. El Sayed, Wael A. El Shafie
Cord Blood Albumin–Bilirubin As A Predictor For Neonatal Hyperbilirubinemia, Ghada M. El Mashad, Hanan M. El Sayed, Wael A. El Shafie
Menoufia Medical Journal
Objective The aim was to evaluate the predictive value of cord blood albumin and bilirubin in identifying infants greater than or equal to 35 weeks for subsequent hyperbilirubinemia. Background Hyperbilirubinemia is the most common cause for readmission during the early neonatal period. Early discharge of healthy term newborns after delivery has become a common practice for socioeconomic reasons. Patients and methods A prospective cohort study was carried out on 75 neonates, greater than or equal to 35 weeks, with 34 female and 41 male neonates, delivered in Menoufia University hospital during the period from June 2016 to December 2017. Full …
Correlation Between Serum Tumor Necrosis Factor-Α Levels And Clinicoradiological Severity Of Tuberculosis, Ahmed A. Ali, Fatma S. El-Fakharany, Ibrahim I. El-Mahalawy, Mona S. Habib, Samy S. El-Dahdouh
Correlation Between Serum Tumor Necrosis Factor-Α Levels And Clinicoradiological Severity Of Tuberculosis, Ahmed A. Ali, Fatma S. El-Fakharany, Ibrahim I. El-Mahalawy, Mona S. Habib, Samy S. El-Dahdouh
Menoufia Medical Journal
Objective The aim was to assess the level of tumor necrosis factor-α (TNF-α) in patients with active pulmonary tuberculosis (TB) and its relation to BMI; different radiological features whether the lesion is minimally, moderately advanced, and far advanced; and to follow-up the level of TNF-α. Background One of the most important and common complaints of patients with TB, which also affects the immune status, is weight loss. When tuberculous infection occurs, a variety of chemokines and cytokines are secreted from infected cells and tissue macrophages. TNF-α increases early in the disease and takes part in the pathogenesis and prevention of …
Right Liver Lobe Diameter/Serum Albumin Ratio In The Prediction Of Esophageal Varices In Cirrhotic Patients, Ahmad Y. H. Metwally, Moamena S. El-Hamouly, Mohamed A. Nouh, Safaa A. Mohamed
Right Liver Lobe Diameter/Serum Albumin Ratio In The Prediction Of Esophageal Varices In Cirrhotic Patients, Ahmad Y. H. Metwally, Moamena S. El-Hamouly, Mohamed A. Nouh, Safaa A. Mohamed
Menoufia Medical Journal
Objective This study aimed to assess the role of right liver lobe diameter by ultrasound/albumin ratio in the prediction of esophageal varices (OV) in cirrhotic patients. Background OV often develop in cirrhotic patients. Varices rupture leading to variceal bleeding represents the most lethal complication of cirrhosis. Right liver lobe diameter/albumin (RLLD/Alb) ratio is a noninvasive method to predict the presence of OV. Patients and methods A case–control study was carried out on 200 cirrhotic patients (145 with OV and 55 without OV). Patients were subjected to complete blood picture, liver and kidney functions, viral markers, abdominal ultrasonography, upper gastrointestinal tract …
Evaluation Of The Relationship Between Glutathione Peroxidase 1 Polymorphism And Hepatocellular Carcinoma, Belal A. Montaser, Gehan K. El-Saeid, Heba S. Mohammed Ghanem, Mohammed A. Rady, Sara M A Aboagiza
Evaluation Of The Relationship Between Glutathione Peroxidase 1 Polymorphism And Hepatocellular Carcinoma, Belal A. Montaser, Gehan K. El-Saeid, Heba S. Mohammed Ghanem, Mohammed A. Rady, Sara M A Aboagiza
Menoufia Medical Journal
Objective The objective of this study was to investigate association of genetic polymorphism of glutathione peroxidase 1 (rs1050450) with liver fibrosis and hepatocellular carcinoma (HCC). Materials and methods Electronic searches were conducted in PubMed, Embase and Cochrane Library from the start of the database to 2017. The initial search presented 215 articles of which 20 met the inclusion criteria. The articles studied the relation between glutathione peroxidase 1 (GPX1) and liver fibrosis and HCC. Extraction was performed, including the assessment of the quality and the validity of the papers that met with the prior criteria that describe the …
Effect Of Adiponectin And Highly Sensitive C-Reactive Protein On The Severity Of Coronary Artery Disease, Ahmed A. Reda, Ahmed O. Elsisy, Waleed A. Ibrahim
Effect Of Adiponectin And Highly Sensitive C-Reactive Protein On The Severity Of Coronary Artery Disease, Ahmed A. Reda, Ahmed O. Elsisy, Waleed A. Ibrahim
Menoufia Medical Journal
Objective The objective of our study was to estimate the effect of adiponectin (ADPN) and highly sensitive C-reactive protein (hsCRP) level on the severity of coronary artery disease (CAD) in patients with chronic stable angina. Materials and methods MEDLINE databases (PubMed, Journal of Clinical Endocrinology and Metabolism, British Medical Journal, Journal of American College of Cardiology, and European Heart Journal) and also materials available in the internet were searched. The search was performed in the electronic databases from 2000 to 2017. The initial search presented 122 articles of which 29 met the inclusion criteria. The articles …
Predictive Prognostic Value Of Neutrophil-Lymphocytes Ratio In Acute Coronary Syndrome, Ahmed A. Reda, Markos Z. Salama, Waleed A. Ibrahim
Predictive Prognostic Value Of Neutrophil-Lymphocytes Ratio In Acute Coronary Syndrome, Ahmed A. Reda, Markos Z. Salama, Waleed A. Ibrahim
Menoufia Medical Journal
Objective To evaluate the relations between preprocedural neutrophil/lymphocyte (N/L) ratio and in-hospital outcomes in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). Data sources We utilize the medical journals, medical text books, and Medline databases (PubMed, Medscape, and Science Direct) which have updated research with keywords 'neutrophil/lymphocyte ratio and acute coronary syndrome' in the title of the paper and all materials available on the Internet from 2013 to 2017. Study selection The initial search presented 1270 articles of which 21 met the inclusion criteria. The articles studied the correlation between N/L ratio and the occurrence of …
The Value Of Serum Zinc In Early Detection Of Nephropathy In Type 2 Diabetic Patients, Ahmed R. Tawfeek, Mahmoud A.E.A. Kora, Mahmoud A. Sakr
The Value Of Serum Zinc In Early Detection Of Nephropathy In Type 2 Diabetic Patients, Ahmed R. Tawfeek, Mahmoud A.E.A. Kora, Mahmoud A. Sakr
Menoufia Medical Journal
Objective The aim of this research was to study the value of serum zinc in early detection of nephropathy in patients with type 2 diabetes. Background Zinc is involved in multiple aspects of cellular metabolism. It is required for the catalytic activity of nearly 100 enzymes and it plays a major role in immunity, protein synthesis, wound healing, DNA synthesis, and cell division. Zinc is also important for normal growth and development during pregnancy, childhood, and adolescence, and is required for proper sense of taste and smell. A daily intake of zinc is required to keep a steady state because …
Thyroid In Patients Receiving New Direct-Acting Antiviral Agents For Treatment Of Hepatitis C Virus, Belal A. Montaser, Mohamed A. Shaaban, Mohamed Z. Nouh, Mukhtar R. Al-Shabrawy, Walid A. Shehab El-Din
Thyroid In Patients Receiving New Direct-Acting Antiviral Agents For Treatment Of Hepatitis C Virus, Belal A. Montaser, Mohamed A. Shaaban, Mohamed Z. Nouh, Mukhtar R. Al-Shabrawy, Walid A. Shehab El-Din
Menoufia Medical Journal
Objective The aim was to judge thyroid dysfunction in patients receiving new direct-acting antiviral agents (DAAs) for treatment of hepatitis C pathogen. Background Persistent hepatitis C is a gradually progressive disease. DAAs provide high sustained viral response rates and much reduced adverse effects and impaired health-related quality of life during treatment. Patients and methods The analysis included 100 patients with persistent hepatitis C contamination with normal thyroid functions before starting treatment with DAAs. After obtaining written informed consent, all patients were analyzed and clinically assessed. Laboratory investigations including complete blood picture, assessment of liver organ and kidney function, thyroid-stimulating hormone, …
Dialysis Vintage And Risk Factors Of Hyperparathyroidism In Hemodialysis Patients, Ahmed R. Al Arbagy, Mahmoud M. Emara, Mahmoud A. Elsayed, Yassein S. Yassein
Dialysis Vintage And Risk Factors Of Hyperparathyroidism In Hemodialysis Patients, Ahmed R. Al Arbagy, Mahmoud M. Emara, Mahmoud A. Elsayed, Yassein S. Yassein
Menoufia Medical Journal
Objective The objective of this study was to study the risk factors of hyperparathyroidism based on hemodialysis vintage (duration in months or years that hemodialysis patients spend on dialysis). Background Hyperparathyroidism is associated with high risk of fractures, cardiovascular morbidity, and death; therefore, it is important to identify risk factors predicting or influencing parathyroid gland secretion. Patients and methods Patients were divided into two groups: short dialysis vintage (<10 years), and long dialysis vintage (≥10 years). Each group was further divided at parathyroid hormone (PTH) cutoff value of 300 pg/ml. Results Short dialysis vintage patients with PTH more than 300 pg/ml have higher alkaline phosphatase (147.9 ± 101.4 vs. 102.1 ± 89.18; P = 0.009), phosphorus (5.913 ± 1.621 vs. 5.044 …
Study Of Serum Level Of Vascular Endothelial Growth Factor In Patients With Hepatocellular Carcinoma, Ashraf G. Dala, Fathia I. Elbassal, Mohamed H. Badr, Mohamed A. A. Al Diyar
Study Of Serum Level Of Vascular Endothelial Growth Factor In Patients With Hepatocellular Carcinoma, Ashraf G. Dala, Fathia I. Elbassal, Mohamed H. Badr, Mohamed A. A. Al Diyar
Menoufia Medical Journal
Objective The aim of this study was to investigate the role of serum vascular endothelial growth factor (VEGF) as a marker for diagnosis and early detection of hepatocellular carcinoma (HCC). Background HCC is one of the most common malignancies. VEGF is a master regulator of angiogenesis in normal and malignant tissues. Participants and methods This was a cross-sectional study that was carried out in the Internal Medicine Department of El Menoufia University Hospital, Menoufia, throughout the period from July 2016 to April 2017. This research included three groups: group 1 included 40 cirrhotic patients with HCC, group 2 included 40 …
Urinary Podocalyxin And Cyclophilin A: Markers For Early Detection Of Type 2 Diabetic Nephropathy, Belal A. Montasr, Doaa S. Mohamed, Gehan K. El-Saeed, Thoria A. Omar, Walid A. Shehab El-Deen
Urinary Podocalyxin And Cyclophilin A: Markers For Early Detection Of Type 2 Diabetic Nephropathy, Belal A. Montasr, Doaa S. Mohamed, Gehan K. El-Saeed, Thoria A. Omar, Walid A. Shehab El-Deen
Menoufia Medical Journal
Objective To investigate urinary podocalyxin (PCX) and cyclophilin A (CypA) as useful markers for early detection of type 2 diabetic nephropathy (DN). Background PCX is a transmembrane protein that localizes to the apical cell of glomerular podocytes. PCX maintains podocytes shape. PCX is shed from injured podocytes into urine as small vesicles. CypA is an 18-kD protein that is distributed in the cytoplasm and facilitates protein folding and trafficking. It acts as a cellular receptor for cyclosporine A. The expression of CypA is quite high in the kidney, where proximal tubular epithelial cells contain more CypA than other kidney tissues. …
Evaluation Of Transthoracic Sonography In Patients With Interstitial Lung Diseases, Ahmed Abd El-Rahman El-Asdody, Mohammed Abd El-Sattar Agha, Naglaa S. B. Mehana, Osama F. Mansour
Evaluation Of Transthoracic Sonography In Patients With Interstitial Lung Diseases, Ahmed Abd El-Rahman El-Asdody, Mohammed Abd El-Sattar Agha, Naglaa S. B. Mehana, Osama F. Mansour
Menoufia Medical Journal
Objective The aim of this study was to determine the diagnostic value of lung ultrasound (US) in the detection of interstitial lung diseases (ILDs), and to assess the correlations of these features with diagnostic parameters of the disease. Background Chest US can be used as a complementary method for the diagnosis of ILDs especially in situations where chest computed tomography is not available, where bilateral B lines, thickened pleura, irregular pleura, and subpleural lesions are found. Patients and methods This study was carried out on 53 patients ranging in age from 47 to 60 years (21 men and 32 women) …
The Role Of Portal Congestion Index In Prediction Of Esophageal Varices In Hepatitis C Virus-Infected Patients, Maha M. Hana, Moamena S. El-Hammoly, Mohamed A. Nouh, Safaa A. Mohamed
The Role Of Portal Congestion Index In Prediction Of Esophageal Varices In Hepatitis C Virus-Infected Patients, Maha M. Hana, Moamena S. El-Hammoly, Mohamed A. Nouh, Safaa A. Mohamed
Menoufia Medical Journal
Objective To assess the role of portal congestion index (PCI) in prediction of esophageal varices (EV) in hepatitis C virus (HCV)-infected patients. Background Portal hypertension (PH) often develops in HCV-infected patients. EV rupture leads to variceal bleeding, the most lethal complication of cirrhosis. Duplex Doppler ultrasonography of portal vein is a noninvasive method to assess blood flow velocity and portal vein cross-sectional area as a parameter for PH. Patients and methods This study was conducted on 200 HCV-infected patients (116 with EV and 84 without EV). Patients were subjected to complete blood picture, liver and kidney functions, serum electrolytes, viral …
Study Of Serum Lipid Profile Before And After Hepatitis C Virus Treatment, Ayman M. El-Lehleh, Marwa M. El-Shiekh, Moamena S. El-Hamouly
Study Of Serum Lipid Profile Before And After Hepatitis C Virus Treatment, Ayman M. El-Lehleh, Marwa M. El-Shiekh, Moamena S. El-Hamouly
Menoufia Medical Journal
Objective To study the lipid profile in hepatitis C virus (HCV) patients before and after treatment with daclatasvir (DAV)+sofosbuvir (SOF)±ribavirin (RBV) to determine the effect of virus clearance on the lipid profile. Background Chronic HCV infection is associated with lipid and lipid protein metabolism disorders. There is a marked increase in serum low-density lipoprotein-cholesterol (LDL-C) in HCV-infected patients treated with SOF and RBV. Participants and methods A total of 100 chronic hepatitis C patients were included in a case–control study from February 2017 to August 2017. Twenty healthy individuals volunteered as a control group. Lipid profile changes were analyzed at …
The Role Of Antibiotic Prophylaxis In The Prevention Of Surgical-Site Infection After Hernioplasty In Menoufia University Hospital, Ahmed Gaber, Mahmoud M. A. Al-Rahawy, Samir M. H. Kahla
The Role Of Antibiotic Prophylaxis In The Prevention Of Surgical-Site Infection After Hernioplasty In Menoufia University Hospital, Ahmed Gaber, Mahmoud M. A. Al-Rahawy, Samir M. H. Kahla
Menoufia Medical Journal
Objective The aim of this paper was to evaluate the effectiveness of prophylactic antibiotics in the prevention of postoperative wound infection after Lichtenstein open mesh inguinal hernia repair. Background Inguinal hernia is one of the most common conditions encountered in clinical practice. Mesh repair is becoming the most popular technique for the repair of inguinal hernia. A surgical-site infection is defined as an infection that occurs at or near a surgical incision within 30 days of the procedure or within three months if an implant is left in place. The decision of perioperative antibiotic prophylaxis is made according to a …
The Role Of Osteopontin In Dermatological Diseases, Alaa H. Marea, Amany M. Mohsen, Sally M. El-Hefnawy, Wafaa A. Shehata
The Role Of Osteopontin In Dermatological Diseases, Alaa H. Marea, Amany M. Mohsen, Sally M. El-Hefnawy, Wafaa A. Shehata
Menoufia Medical Journal
Objective The aim of this study was to study the role of osteopontin (OPN) in dermatological diseases through a meta-analysis study. Data sources Previous literatures, reviews, and studies as well as medical websites (PubMed, Medscape and Science Direct), all material available in the internet from 2014 to 2017, and scientific journals databases were searched from the start date of each database. Study selection The initial search presented 10 articles of which five met the inclusion criteria. Selection was done by supervisors for studying the role of OPN in dermatological diseases. Data extraction If the studies did not fulfill the inclusion …
Role Of Microneedling In Treatment Of Patients With Striae Distensae, Hanan A E Mahmoud, Magda M. Hagag, Rehab M. Samaka
Role Of Microneedling In Treatment Of Patients With Striae Distensae, Hanan A E Mahmoud, Magda M. Hagag, Rehab M. Samaka
Menoufia Medical Journal
Objective The aim of this work was to elucidate the efficacy and safety of microneedling in the treatment of striae distensae (SD). Background SD is a common form of dermal scarring that appears on the skin as violaceous, erythematous, or hypopigmented linear striations. Microneedling therapy or collagen induction therapy is a minimally invasive, nonsurgical, and nonablative procedure that involves the use of a microneedling device to create controlled skin injury. Data sources Medline databases such as PubMed, Medscape, Science Direct, and EMF-Portal and all materials available on the Internet from 2010 to 2017 were searched. Study selection The initial search …