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Medicine and Health Sciences Commons

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Edith Cowan University

2012

Obesity

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Sirtuin-1 Mediates The Obesity Induced Risk Of Common Degenerative Diseases: Alzheimer's Disease, Coronary Artery Disease And Type 2 Diabetes, Ian Martins, Andrea Wilson, Wei Ling Lim, Simon Laws, Stephanie Fuller, Ralph Martins Jan 2012

Sirtuin-1 Mediates The Obesity Induced Risk Of Common Degenerative Diseases: Alzheimer's Disease, Coronary Artery Disease And Type 2 Diabetes, Ian Martins, Andrea Wilson, Wei Ling Lim, Simon Laws, Stephanie Fuller, Ralph Martins

Research outputs 2012

Obesity, especially at mid-life, is a major risk factor for atherosclerosis, insulin resistance and the metabolic syndrome, which in turn contrib- ute to coronary artery disease (CAD), Type 2 diabetes and Alzheimer’s disease (AD). The rise in overweight and obesity in all societies is prompting intense research into the causes and effects of the condition. Obesity disrupts many body systems including glucose and lipid me- tabolism, circadian rhythms and liver function. It also causes or increases inflammation and oxi- dative stress. Within cells, the endoplasmic re- ticulum (ER) appears to be particularly suscep- tible to such metabolic disruption. Sirtuin 1 …


Early Diet Quality In A Longitudinal Study Of Australian Children: Associations With Nutrition And Body Mass Index Later In Childhood And Adolescence, Claire Meyerkort, Wendy H. Oddy, Therese O'Sullivan, J Henderson, Craig Pennell Jan 2012

Early Diet Quality In A Longitudinal Study Of Australian Children: Associations With Nutrition And Body Mass Index Later In Childhood And Adolescence, Claire Meyerkort, Wendy H. Oddy, Therese O'Sullivan, J Henderson, Craig Pennell

Research outputs 2012

Obesity has origins extending to antenatal and early postnatal periods; however, the relationship between early postnatal diet and subsequent obesity is not well defined. The aims of this study were to determine whether early childhood dietary quality was associated with (a) infant and adolescent nutrition and (b) body mass index (BMI) in childhood and adolescence. The degree to which early nutrition and growth factors determine BMI throughout childhood and adolescence was also explored. This research was conducted using the Raine Study, a longitudinal survey of Australian children assessed from mid-gestation to 17 years of age. A dietary quality index, the …