Medicine and Health Sciences Commons^™

Nitrate: The Dr. Jekyll And Mr. Hyde Of Human Health?, Catherine P. Bondonno, Liezhou Zhong, Nicola P. Bondonno, Marc Sim, Lauren C. Blekkenhorst, Alex Liu, Anjana Rajendra, Pratik Pokharel, Dorit W. Erichsen, Oliver Neubauer, Kevin D. Croft, Jonathan M. Hodgson

Research outputs 2022 to 2026

Background: Dietary nitrate has a controversial role in human health. For over half a century, the nitrate content of the three major dietary sources – vegetables, meat, and water – has been legislated, regulated, and monitored due to public health concerns over cancer risk. In contrast, a growing and compelling body of evidence indicates that dietary nitrate, particularly from vegetables, protects against cardiovascular disease and other chronic diseases. This evidence for the protective effect of nitrate is overshadowed by the potential for nitrate to form carcinogenic N-nitrosamines. Scope and approach: The nitrate content, regulations and estimated intake from vegetables, meat …

Overview Of Aboriginal And Torres Strait Islander Health Status 2022, Australian Indigenous Healthinfonet, Neil Drew, Ashleigh Parnell, Christine Potter, Miranda Poynton, Hannah Tarrant

Research outputs 2022 to 2026

The main purpose of the Overview of Aboriginal and Torres Strait Islander health status (Overview) is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander people. The Overview has been prepared by HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key indicator of the HealthInfoNet’s commitment to authentic and engaged knowledge development and exchange. The initial sections of this Overview provide information about the context of Aboriginal and …

Exploring The Re-Legitimisation Of Messages For Health And Physical Education Within Contemporary English And Welsh Curricula Reform, J. Stirrup, David Aldous, S. Gray, R. Sandford, O. Hooper, S. Hardley, A. S. Bryant, N. R. Carse

Research outputs 2022 to 2026

This paper explores how messages for health and PE ([H]PE) within English and Welsh curricula are being re-legitimised through distinct performance and competence pedagogic models. Drawing upon Bernstein’s sociology of knowledge (Bernstein, 1996. Pedagogy, symbolic control and identity: Theory, research, critique. Taylor and Francis; 2000. Pedagogy, symbolic control and identity: Theory, research and critique (revised ed.). Rowman and Littlefield) data was generated through a deductive content analysis of the contemporary statutory English National Curriculum for Physical Education (NCPE) and the new Curriculum for Wales (CfW), Health and Well-Being Area of Learning and Experience (HWB-AoLE). Findings illustrate how the current English …

Investigating Pre-Professional Dancer Health Status And Preventative Health Knowledge, Joanna Nicholas, Sara Grafenauer

Research outputs 2022 to 2026

Introduction: Dance is a highly demanding physical pursuit coupled with pressure to conform to aesthetic ideals. Assessment of health status and preventative health knowledge of pre-professional dancers may help inform educational strategies promoting dancers’ health and career longevity. The aim of this research was to establish a baseline understanding of dance students at a single pre-professional institution based on metrics focused on current health, nutrition, lifestyle, and wellbeing while also gauging knowledge of longer-term health implications. Methods: Adopting a cross-sectional study design, the Dance-Specific Energy Availability Questionnaire was tailored for Australian participants and administered online. Results: The response rate was …

Summary Of Alcohol And Drug Treatment For Aboriginal And Torres Strait Islander Peoples, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

This summary is based on the Review of alcohol and drug treatment for Aboriginal and Torres Strait Islander peoples. It provides an overview of the available evidence for treatment approaches to help a person reduce or stop substance use. These are treatments for when a person has evidence of either hazardous use or problem alcohol and other drug (AOD) use (see Box 1 for terms used). Some approaches to address substance use are not included in this summary (e.g. for tobacco cessation or volatile substance use). This summary presents information on:

• the available research and other evidence that underpins …

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2022, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

The Summary of Aboriginal and Torres Strait Islander health status - selected topics 2022 (Summary) is a useful resource for those working or studying in the Aboriginal and Torres Strait Islander health sector. It provides general information regarding the health status of Aboriginal and Torres Strait Islander people covering the following topics:

• the Aboriginal and Torres Strait Islander population
• determinants of health
• information pertaining to births and pregnancy, deaths and hospitalisation
• burden of disease
• chronic conditions including cardiovascular disease, cancer, diabetes, kidney and respiratory health
• social and emotional wellbeing (including mental health)
• selected sexually transmissible infections
• environmental health
• tobacco and …

Preference For Male Risk Takers Varies With Relationship Context And Health Status But Not Covid Risk, Cyril C. Grueter, Hannah Goodman, Nicolas Fay, Bradley Walker, David Coall

Research outputs 2022 to 2026

Risk taking is more commonly shown by males than females and has a signalling function, serving to advertise one’s intrinsic quality to prospective mates. Previous research has established that male risk takers are judged as more attractive for short-term flings than long-term relationships, but the environmental and socioeconomic context surrounding female preferences for male risk takers has been overlooked. Using a survey instrument, we examined female preferences for male risk takers across 1304 females from 47 countries. We found preferences for physical risk takers to be more pronounced in females with a bisexual orientation and females who scored high on …

Female Athlete Health Domains: A Supplement To The International Olympic Committee Consensus Statement On Methods For Recording And Reporting Epidemiological Data On Injury And Illness In Sport, Isabel S. Moore, Kay M. Crossley, Kari Bo, Margo Mountjoy, Kathryn E. Ackerman, Juliana D. S. Antero, Jorunn S. Borgen, Wendy J. Brown, Caroline S. Bolling, Benjamin Clarsen, Wayne Derman, Paul Dijkstra, Amber Donaldson, Kirsty J. Elliott-Sale, Carolyn A. Emery, Lene Haakstad, Astrid Junge, Nonhlanhla S. Mkumbuzi, Sophia Nimphius, Debbie Palmer, Mireille Van Poppel, Jane S. Thornton, Rita Tomás, Phathokuhle C. Zondi, Evert Verhagen

Research outputs 2022 to 2026

The IOC made recommendations for recording and reporting epidemiological data on injuries and illness in sports in 2020, but with little, if any, focus on female athletes. Therefore, the aims of this supplement to the IOC consensus statement are to (i) propose a taxonomy for categorisation of female athlete health problems across the lifespan; (ii) make recommendations for data capture to inform consistent recording and reporting of symptoms, injuries, illnesses and other health outcomes in sports injury epidemiology and (iii) make recommendations for specifications when applying the Strengthening the Reporting of Observational Studies in Epidemiology-Sport Injury and Illness Surveillance (STROBE-SIIS) …

Summary Of Cannabis Use Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

This Summary is based on the Review of cannabis use among Aboriginal and Torres Strait Islander people. The review summarises the evidence from journal publications, government reports, national data collections and national surveys accessed through the HealthInfoNet’s database of publications. Please note that statistics presented do not always include all states and territories, see sources for details. ...

Summary Of Diabetes Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet, Kathy Ride

Research outputs 2022 to 2026

This publication, in plain language, is based on information presented in the Review of diabetes among Aboriginal and Torres Strait Islander people (2022). This short, visual report summarises the key findings and concepts from the review to provide a holistic picture of diabetes among Aboriginal and Torres Strait Islander people. It is a quick source of information covering:

• the social and cultural context of diabetes, and the behavioural and biomedical factors that contribute to diabetes among Aboriginal and Torres Strait Islander people
• the extent of diabetes among Aboriginal and Torres Strait Islander people, including incidence and prevalence data; hospitalisations; mortality …

Overview Of Aboriginal And Torres Strait Islander Health Status, 2021, Australian Indigenous Healthinfonet, Neil Drew, Ashleigh Parnell, Christine Potter, Miranda Poynton

Research outputs 2022 to 2026

The main purpose of the Overview of Aboriginal and Torres Strait Islander health status (Overview) is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander people. The Overview has been prepared by HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key indicator of the HealthInfoNet’s commitment to authentic and engaged knowledge development and exchange. The initial sections of this Overview provide information about the context of Aboriginal and …

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2021, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

...The HealthInfoNet has prepared this Summary as part of our contribution to support those who work in the Aboriginal and Torres Strait Islander health sector. Key health topics are summarised in plain language and an infographic style to enable readers to absorb data easily and quickly...

Major Genetic Discontinuity And Novel Toxigenic Species In Clostridioides Difficile Taxonomy, Daniel R. Knight, Korakrit Imwattana, Brian Kullin, Enzo Guerrero-Araya, Daniel Paredes-Sabja, Xavier Didelot, Kate E. Dingle, David W. Eyre, César Rodríguez, Thomas V. Riley

Research outputs 2014 to 2021

Clostridioides difficile infection (CDI) remains an urgent global One Health threat. The genetic heterogeneity seen across C. difficile underscores its wide ecological versatility and has driven the significant changes in CDI epidemiology seen in the last 20 years. We analysed an international collection of over 12,000 C. difficile genomes spanning the eight currently defined phylogenetic clades. Through whole-genome average nucleotide identity, and pangenomic and Bayesian analyses, we identified major taxonomic incoherence with clear species boundaries for each of the recently described cryptic clades CI–III. The emergence of these three novel genomospecies predates clades C1–5 by millions of years, rewriting the …

Prevalence Of Frailty And Pain In Hospitalised Adult Patients In An Acute Hospital: A Protocol For A Point Prevalence Observational Study, Rosemary Saunders, Kate Crookes, Mustafa Atee, Caroline Bulsara, Max K. Bulsara, Christopher Etherton-Beer, Beverley Ewens, Olivia Gallagher, Renee M. Graham, Karen Gullick, Sue Haydon, Kim-Huong Nguyen, Bev O'Connell, Karla Seaman, Jeff Hughes

Research outputs 2014 to 2021

Introduction Frailty and pain are associated with adverse patient clinical outcomes and healthcare system costs. Frailty and pain can interact, such that symptoms of frailty can make pain assessment difficult and pain can exacerbate the progression of frailty. The prevalence of frailty and pain and their concurrence in hospital settings are not well understood, and patients with cognitive impairment are often excluded from pain prevalence studies due to difficulties assessing their pain. The aim of this study is to determine the prevalence of frailty and pain in adult inpatients, including those with cognitive impairment, in an acute care private metropolitan …

Fecal Sample Collection Methods And Time Of Day Impact Microbiome Composition And Short Chain Fatty Acid Concentrations, Jacquelyn Jones, Stacey N. Reinke, Alishum Ali, Debra J. Palmer, Claus T. Christophersen

Research outputs 2014 to 2021

Associations between the human gut microbiome and health outcomes continues to be of great interest, although fecal sample collection methods which impact microbiome studies are sometimes neglected. Here, we expand on previous work in sample optimization, to promote high quality microbiome data. To compare fecal sample collection methods, amplicons from the bacterial 16S rRNA gene (V4) and fungal (ITS2) region, as well as short chain fatty acid (SCFA) concentrations were determined in fecal material over three timepoints. We demonstrated that spot sampling of stool results in variable detection of some microbial members, and inconsistent levels of SCFA; therefore, sample homogenization …

Overview Of Aboriginal And Torres Strait Islander Health Status, 2020, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

The Overview of Aboriginal and Torres Strait Islander health status (the Overview) aims to provide a comprehensive outline of the most recent indicators of the health and current health status of Australia's Aboriginal and Torres Strait Islander people. The initial sections of the Overview provide information about the context of Aboriginal and Torres Strait Islander health, social determinants, the Aboriginal and Torres Strait Islander population and measures of population health status including births, mortality and hospitalisation...

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2020, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

The Summary of Aboriginal and Torres Strait Islander health status - selected topics 2020 is a useful source of the most recent national information for health workers and those studying in the field. It provides general information regarding the health status of Aboriginal and Torres Strait Islander people across the following topics:

• social and cultural determinants
• births and deaths
• hospitalisations
• chronic conditions (including CVD, cancer, diabetes and kidney health)
• sexually transmitted infections
• environmental health
• social and emotional wellbeing
• alcohol and other drug use.

The Summary is based on the Overview of Aboriginal and Torres Strait Islander health status 2020 and …

Summary Of Sexual Health Links With Chronic Disease In Aboriginal And Torres Strait Islander Males, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

This Summary is based on the Review of sexual health issues linked with cardiovascular disease and type 2 diabetes mellitus in Aboriginal and Torres Strait Islander males (the ‘Review’) ^[1] published by the Australian Indigenous HealthBulletin in 2021. It provides information about the male sexual health conditions of erectile dysfunction (ED) and low testosterone, and their links to chronic disease, specifically cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). It outlines:

• the causes and symptoms of ED and low testosterone
• how common ED and low testosterone are among the Australian male population (there are limited data available about Aboriginal …

Summary Of Methamphetamine Use Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

The Summary of methamphetamine use among Aboriginal and Torres Strait Islander people is a plain language publication that provides summarised and updated information from the Review of methamphetamine use among Aboriginal and Torres Strait Islander people(2019). It provides key information about methamphetamine use among Aboriginal and Torres Strait Islander people in a style that is easy to engage with. It is particularly useful for health workers and those studying in the field as a quick source of general information about:

• the physical and mental impacts of methamphetamine
• historical and social factors of use
• how common methamphetamine use is …

Using A Respectful Approach To Child-Centred Healthcare (Reach) In A Paediatric Clinical Trial: A Feasibility Study, Analise Nicholl, Kate Evelegh, Kane Evan Deering, Kate Russell, David Lawrence, Philippa Lyons-Wall, Therese O'Sullivan

Research outputs 2014 to 2021

Background

There is a growing momentum in paediatric ethics to develop respectful research and healthcare protocols. We developed, tested and refined our ‘Respectful Approach to Child-centred Healthcare’ (ReACH), to underpin respectful participant interactions in a clinical trial.

Objective

To determine whether a ReACH-based approach is acceptable to children and parents, and effective in obtaining compliance with common healthcare assessments in a clinical trial of healthy 4-6-year-old children.

Methods

ReACH-based child assessments were evaluated at two baseline clinics and one post-intervention, using mixed methods. Children (n = 49; 46.9% female; mean age = 5.24±0.88 years at baseline) and their parents provided …

Summary Of Aboriginal And Torres Strait Islander Health Status 2019, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

The Summary of Aboriginal and Torres Strait Islander health status 2019 (Summary) provides a brief and current overview of the health of Aboriginal and Torres Strait Islander people in Australia in a plain language and visual style. The Australian Indigenous HealthInfoNet has prepared the Summary as part of our contribution to support those in the Aboriginal and Torres Strait Islander workforce and those participating in research and working with Aboriginal and Torres Strait Islander people and their communities...

Summary Of Kidney Health Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

No abstract provided.

Overview Of Aboriginal And Torres Strait Islander Health Status 2019, Australian Indigenous Healthinfonet, Anomie, Burns Jane, Neil Drew, Michelle Elwell, Vilma Fitzgerald, Joanne Hoareau, Christine Potter, Miranda Poynton, Tamara Swann, Avinna Trzesinski

Research outputs 2014 to 2021

The main purpose of the Overview of Aboriginal and Torres Strait Islander health status (Overview) is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander people. The Overview has been prepared by Australian Indigenous HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key element of the HealthInfoNet’s commitment to authentic and engaged knowledge development and exchange...

Modelling Biological Age Based On Plasma Peptides In Han Chinese Adults, Weijie Cao, Deqiang Zheng, Guohua Wang, Jie Zhang, Siqi Ge, Manjot Singh, Hao Wang, Manshu Song, Dong Li, Wei Wang, Youxin Wang

Research outputs 2014 to 2021

Age-related disease burdens increased over time, and whether plasma peptides can be used to accurately predict age in order to explain the variation in biological indicators remains inadequately understood. Here we first developed a biological age model based on plasma peptides in 1890 Chinese Han adults. Based on mass spectrometry, 84 peptides were detected with masses in the range of 0.6-10.0 kDa, and 13 of these peptides were identified as known amino acid sequences. Five of these thirteen plasma peptides, including fragments of apolipoprotein A-I (m/z 2883.99), fibrinogen alpha chain (m/z 3060.13), complement C3 (m/z 2190.59), complement C4-A (m/z 1898.21), …

Summary Of Nutrition Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

No abstract provided.

Summary Of Tobacco Use Among Aboriginal And Torres Strait Islander Peoples, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

The Summary of tobacco use among Aboriginal and Torres Strait Islander peoples is a plain language publication that provides summarised and updated information from the Review of tobacco use among Aboriginal and Torres Strait Islander peoples(2020). It provides key information about tobacco use among Aboriginal and Torres Strait Islander peoples in a style that is easy to engage with and is particularly useful for health workers and those studying in the field as a quick source of general information about:

• the context of tobacco use and how common tobacco use is
• how smoking affects health
• the burden of disease …

Summary Of Cardiovascular Health Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

This Summary describes different types of cardiovascular disease (CVD) and how common they are among Aboriginal and Torres Strait Islander people. It highlights the differences in how groups of Aboriginal and Torres Strait Islander people – such as women and men, or older and younger people – experience CVD. It describes some improvements in the cardiovascular health of Aboriginal and Torres Strait Islander people. It also gives examples of the many good things that are being done on the ground to prevent illness and improve CVD care for Aboriginal and Torres Strait Islander people.

Implementation, Mechanisms Of Impact And Key Contextual Factors Involved In Outcomes Of The Modification Of Diet, Exercise And Lifestyle (Model) Randomised Controlled Trial In Australian Adults: Protocol For A Mixed-Method Process Evaluation, Reindolf Anokye, Simone Radavelli-Bagatini, Catherine P. Bondonno, Marc Sim, Lauren C. Blekkenhorst, Emma Connolly, Nicola P. Bondonno, John T. Schousboe, Richard Woodman, Kun Zhu, Pawel Zhu, Ben Jackson, James Dimmock, Markus P. Schlaich, Kay L. Cox, Douglas P. Kiel, Wai H. Lim, Amanda Devine, Peter L. Thompson, Jenny Gianoudis, Belinda De Ross, Robin M. Daly, Jonathan M. Hodgson, Joshua Lewis, Mandy Stanley

Research outputs 2014 to 2021

Introduction

The Modification of Diet, Exercise and Lifestyle (MODEL) study aims to examine the impact of providing visualisation and pictorial representation of advanced structural vascular disease (abdominal aortic calcification), on ‘healthful’ improvements to diet and lifestyle. This paper reports the protocol for the process evaluation for the MODEL study.

Methods and analysis

The overall aim of the process evaluation is to understand the processes that took place during participation in the MODEL study trial and which elements were effective or ineffective for influencing ‘healthful’ behavioural change, and possible ways of improvement to inform wider implementation strategies. A mixed-method approach will …

A Bitter Pill To Swallow: Registered Nurses And Medicines Regulation In Remote Australia, Katie R. Pennington, Kim D. Clark, Sabina Knight

Research outputs 2014 to 2021

INTRODUCTION: Access to essential medicines is a human right and an objective of the National Medicines Policy in Australia. Health workforce distribution characteristics in remote Australia implies registered nurses (RNs) may find themselves responsible for a broader range of activities in the medication management cycle than they would be elsewhere in the nation. The regulation of health professionals and their training requirements provides essential but complex protections for the public. These protections include the National Registration and Accreditation Scheme for health practitioners and the Australian Health Practitioner Regulation Agency. Other levels of control or regulation are also exerted over health …

Igg Glycosylation Profile And The Glycan Score Are Associated With Type 2 Diabetes In Independent Chinese Populations: A Case-Control Study, Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

Background. The relationship between the IgG glycan panel and type 2 diabetes remains unclear in Chinese population. We aimed to investigate the association of the IgG glycan profile and glycan score with type 2 diabetes. Methods. In the discovery population, 162 individuals diagnosed with type 2 diabetes and 162 matched controls from Beijing health management cohort were included. We analyzed the IgG glycan profile and composed a glycan score for type 2 diabetes. Findings were validated in the replication population from Beijing Xuanwu community cohort (280 cases and 508 controls). Area under curve (AUC) using 10-fold and bootstrap validation, net …