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Full-Text Articles in Medicine and Health Sciences
Experiences And Perspectives Of Children And Young People Living With Childhood-Onset Systemic Lupus Erythematosus—An Integrative Review, Julie Blamires, Mandie Foster, Sara Napier, Annette Dickinson
Experiences And Perspectives Of Children And Young People Living With Childhood-Onset Systemic Lupus Erythematosus—An Integrative Review, Julie Blamires, Mandie Foster, Sara Napier, Annette Dickinson
Research outputs 2022 to 2026
Childhood-onset systemic lupus erythematosus (cSLE) impacts the daily life of children and young people. This study aimed to describe the experiences and perspectives of children and young people living with cSLE. An integrative review guided by Whittemore and Knafl was conducted. Extant empirical research published in peer-reviewed journals from 2000 to 2021 on children’s self-reported experiences living with cSLE was identified from Scopus, CINAHL, Medline via PubMed, and PsycINFO via Ovid databases. Nineteen studies involving over 1400 participants were included. Four themes and fourteen sub-themes were identified: (1) challenging symptoms (disruptions to life and altered self, severity, fatigue, depression, and …
The Role Of Flumazenil In Generalised Anxiety Disorder: A Pilot Naturalistic Open-Label Study With A Focus On Treatment Resistance, Alexander T. Gallo, Stephen Addis, Vlad Martyn, Hishani Ramanathan, Grace K. Wilkerson, Kellie S. Bennett, Sean D. Hood, Hans Stampfer, Gary K. Hulse
The Role Of Flumazenil In Generalised Anxiety Disorder: A Pilot Naturalistic Open-Label Study With A Focus On Treatment Resistance, Alexander T. Gallo, Stephen Addis, Vlad Martyn, Hishani Ramanathan, Grace K. Wilkerson, Kellie S. Bennett, Sean D. Hood, Hans Stampfer, Gary K. Hulse
Research outputs 2022 to 2026
Background: Anxiety disorders are highly prevalent and chronic disorders with treatment resistance to current pharmacotherapies occurring in approximately one in three patients. It has been postulated that flumazenil (FMZ) is efficacious in the management of anxiety disorders via the removal of 4 2 gamma-aminobutyric acid A receptors. Objective: To assess the safety and feasibility of continuous low-dose FMZ infusions for the management of generalised anxiety disorder (GAD) and collect preliminary efficacy data. Design: Uncontrolled, open-label pilot study. Method: Participants had a primary diagnosis of generalised anxiety disorder (GAD) and received two consecutive subcutaneous continuous low-dose FMZ infusions. Each infusion contained …