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Full-Text Articles in Medicine and Health Sciences
A Blood-Based Predictor For Neocortical Aβ Burden In Alzheimer's Disease: Results From The Aibl Study, Samantha Burnham, Noel Faux, William Wilson, Simon Laws, David Ames, Justin Bedo, Ashley Bush, James Doecke, Kathryn Ellis, Richard Head, Gareth Jones, Harri Kiiveri, Ralph N. Martins, Alan Rembach, Christopher Rowe, Olivier Salvado, S Lance Macaulay, Colin Masters, Victor Villemagne
A Blood-Based Predictor For Neocortical Aβ Burden In Alzheimer's Disease: Results From The Aibl Study, Samantha Burnham, Noel Faux, William Wilson, Simon Laws, David Ames, Justin Bedo, Ashley Bush, James Doecke, Kathryn Ellis, Richard Head, Gareth Jones, Harri Kiiveri, Ralph N. Martins, Alan Rembach, Christopher Rowe, Olivier Salvado, S Lance Macaulay, Colin Masters, Victor Villemagne
Research outputs 2013
Dementia is a global epidemic with Alzheimer’s disease (AD) being the leading cause. Early identification of patients at risk of developing AD is now becoming an international priority. Neocortical Aβ (extracellular β-amyloid) burden (NAB), as assessed by positron emission tomography (PET), represents one such marker for early identification. These scans are expensive and are not widely available, thus, there is a need for cheaper and more widely accessible alternatives. Addressing this need, a blood biomarker-based signature having efficacy for the prediction of NAB and which can be easily adapted for population screening is described. Blood data (176 analytes measured in …
Dietary Patterns Associated With Alzheimer's Disease And Related Chronic Disease Risk: A Review, Samantha L. Gardener, Stephanie R. Rainey-Smith, Jennifer Keogh, Suzanne Mathieson, Ralph N. Martins
Dietary Patterns Associated With Alzheimer's Disease And Related Chronic Disease Risk: A Review, Samantha L. Gardener, Stephanie R. Rainey-Smith, Jennifer Keogh, Suzanne Mathieson, Ralph N. Martins
Research outputs 2013
The world’s population is growing older due to improved healthcare and nutrition. As a result, Alzheimer’s disease (AD) prevalence is rapidly increasing. The focus of the current research climate is shifting from understanding AD pathology and diagnosis to primary prevention and intervention strategies. Diet represents one potential intervention strategy accessible to all. Accumulating evidence suggests diet plays a major role in risk and development of AD and AD-related chronic diseases of the periphery like cardiovascular disease (CVD) and diabetes. This paper reviews studies that have explored the relationship between “a priori” dietary patterns, AD and AD-related chronic disease risk. The …