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Full-Text Articles in Medicine and Health Sciences

Thermoregulatory And Exercise Performance : Responses To Cooling With Ice Slurry Ingestion, Rodney Siegel Apr 2011

Thermoregulatory And Exercise Performance : Responses To Cooling With Ice Slurry Ingestion, Rodney Siegel

Theses: Doctorates and Masters

The rise in body core, skin and muscle temperatures associated with exercise
in hot environments (~30°C and above) is known to impair performance over a
variety of exercise modes and durations. Precooling has become a popular strategy to
combat this impairment, as evidence has shown it to be an effective method for
lowering pre-exercise core temperature, increasing heat storage capacity and
improving exercise performance in the heat. To date, the majority of precooling
manoeuvres are achieved via external means, such as cold water immersion and the
application of cooling garments; methods which have been criticised for their lack of
practicality …


An Examination Of The Relationship Between Positive Psychological Functioning And Depression, John Forbes Jan 2011

An Examination Of The Relationship Between Positive Psychological Functioning And Depression, John Forbes

Theses: Doctorates and Masters

With unipolar depression one of the most disabling illnesses in the world, it is important to appropriately conceptualise this disorder in order to inform research, diagnosis, and treatment. While many psychological theories of depression include constructs of polarity, most research and diagnostic criteria have focused on a single dimension that concentrates on the presence of negative symptomatology. This is reflective of an illness model of mental health that predominantly considers the presence of negative symptoms in terms of mood, cognitions, behaviours, and overall functioning. Nevertheless, there is strong research evidence indicating that positive and negative aspects of psychological functioning are …


Approaches To The Spatial Modelling Of Cancer Incidence And Mortality In Metropolitan Perth, Western Australia, 1990 -2005, Changying Shao Jan 2011

Approaches To The Spatial Modelling Of Cancer Incidence And Mortality In Metropolitan Perth, Western Australia, 1990 -2005, Changying Shao

Theses: Doctorates and Masters

Cancer is one of potentially preventable and treatable diseases. Cancer analysis from different perspectives is necessary to provide the information for health research and the initiation of prevention and treatment programs. The purpose of this study was to analyse five top cancers in the Perth metropolitan area, including lung, melanoma, breast, prostate and colorectal cancers, using two methodologies: Area-to-Point Poisson (ATP) kriging and fitting an inhomogeneous Poisson process model using the Berman-Turner algorithm. ATP Poisson kriging was used to undertake the analysis on the spatial distribution of cancer rates per 100,000 person-years for Perth Statistical Local Areas during the period …


Scald Burn Admissions To Princess Margaret Hospital In 1998 And 2008: A Comparative Analysis, Lisa Martin Jan 2011

Scald Burn Admissions To Princess Margaret Hospital In 1998 And 2008: A Comparative Analysis, Lisa Martin

Theses: Doctorates and Masters

Scald is the most common form of burn in young children, accounting for over 50% of all paediatric burn admissions in Western Australia (WA). Interventions implemented over the past few years focussed on prevention, first aid, and improved services postinjury (Department of Health Western Australia, 2009). The population of children in WA is rising and an epidemiological study was undertaken to assess changes in the profile of scald injury among WA children and to assess priorities for future action. Data were collected from all acute inpatient admissions presenting with scald injury for 1998 and 2008. These data were compared with …


Internet Use And Its Impact On Secondary School Students In Chiang Mai, Thailand, Kesaraporn Wanajak Jan 2011

Internet Use And Its Impact On Secondary School Students In Chiang Mai, Thailand, Kesaraporn Wanajak

Theses: Doctorates and Masters

Internet addiction (IA) is a relatively new field of academic inquiry. Empirical studies suggest that IA, like other well researched addictive behaviours, has an effect on many aspects of a person‟s life, including academic/work performance, relationships, and physical and mental health (Goldberg, 1996; Young, 1996, 1998). Evidence of IA has been suggested by the findings that some Internet users spend increasingly longer periods of time online and experience withdrawal symptoms when offline. Those preoccupied with Internet-related activities may neglect exercise, family and social activities (Kim et al., 2010; Nalwa & Anand, 2003; Seo, Kang, & Yom, 2009; S. Yang & …


New Perspectives On Melanoma: The Role Of Pax3, Sandra Medic Jan 2011

New Perspectives On Melanoma: The Role Of Pax3, Sandra Medic

Theses: Doctorates and Masters

Background: Cutaneous melanoma is an aggressive form of skin cancer, arising in cutaneous melanocytes. The transcription factor PAX3 is critical for the proper development of neural crest lineages including melanocytes. Melanocytic cells show continued PAX3 expression from melanoblast formation in the neural crest to their differentiation into melanocytes. While many studies clarify the importance of PAX3 in embryonic development of melanocytes, less well understood, and more perplexing, is the continued PAX3 expression in adult skin melanocytes. By contrast PAX3 is frequently found in melanomas and naevi, and its expression correlates with melanoma staging. In this study we explore the multiple …


Parental And Carer Responses To Angelman Syndrome And Prader-Willi Syndrome, Allyson K. Thomson Jan 2011

Parental And Carer Responses To Angelman Syndrome And Prader-Willi Syndrome, Allyson K. Thomson

Theses: Doctorates and Masters

The research project undertaken as part of this thesis was designed to assess family stress levels and the use of coping strategies among the carers of people with an intellectual disability caused by Angelman syndrome (AS) or Prader-Willi syndrome (PWS). Both syndromes are genomic imprinting disorders that arise from disruptions in genes located within human chromosome 15q11-q13. Although the disease phenotypes are quite distinct, the genetic mechanisms involved are common to both syndromes but involve paternally-derived mutations in PWS as opposed to maternal mutations in AS. Previous investigations in Western Australia (WA) indicated that people with AS and PWS experience …


Feedback Control For Exergames, Jeff Sinclair Jan 2011

Feedback Control For Exergames, Jeff Sinclair

Theses: Doctorates and Masters

The concept of merging exercise equipment with video games, known as exergaming, has the potential to be one of the main tools used in addressing the current rising obesity epidemic. Existing research shows that exergaming can help improve fitness and additionally motivate people to become more active. The two key elements of attractiveness - how much people want to play or use the exergaming system; and effectiveness – how effective the exergaming system is in actually increasing or maintaining physical fitness, need to be maximised to obtain the best outcomes from an exergaming system; we put this forward as the …


Yeast As A Model For Studying Aβ Aggregation, Toxicity And Clearance, Prashant R. Bharadwaj Jan 2011

Yeast As A Model For Studying Aβ Aggregation, Toxicity And Clearance, Prashant R. Bharadwaj

Theses: Doctorates and Masters

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of the central nervous system, characterised by acute memory loss and behavioural symptoms. The AD brain is characterized by the presence of senile amyloid plaques associated with degenerating neurites and inflammatory processes. The major protein component of these amyloid deposits is the amyloid beta (Aβ) protein. The Aβ protein is a 40 or 42 amino acid cleavage product of APP (Amyloid Precursor Protein) which is produced in low levels in the normal ageing brain. Although senile amyloid plaques is the major pathological hallmark of AD brains, accumulating evidence has been presented to …


Effect Of Transcranial Direct Current Stimulation (Tdcs) On Maximal Voluntary Isometric Strength And Endurance Of The Elbow Flexors, Benjamin Kan Jan 2011

Effect Of Transcranial Direct Current Stimulation (Tdcs) On Maximal Voluntary Isometric Strength And Endurance Of The Elbow Flexors, Benjamin Kan

Theses: Doctorates and Masters

The present study investigated the effects of transcranial direct current stimulation (tDCS) on maximal voluntary contraction strength (MVC) and the time to failure (TTF) of an isometric muscle endurance test of the elbow flexors. Prior to the main study, the test-retest reliability of MVC and TTF measures was investigated using 10 men (33.2 ± 9.4 y) for the measurements separated by 60 min (within-day) and one week (between-day). Coefficient of variation (CV), Intraclass correlation (ICC, R), a paired t-test and the Bland-Altman plots revealed that TTF at 30% MVC task was reliable, and was able to detect a possible effect …


Creating Persuasive Messages To Promote Abstinence From Alcohol During Pregnancy, Kathryn France Jan 2011

Creating Persuasive Messages To Promote Abstinence From Alcohol During Pregnancy, Kathryn France

Theses: Doctorates and Masters

While the rates of Fetal Alcohol Spectrum Disorder within Australia are unknown, the rates of alcohol use during pregnancy and at-risk alcohol use by women of childbearing age highlight the need for universal prevention strategies addressing prenatal alcohol exposure. Though many awareness-raising campaigns for alcohol use during pregnancy have been conducted, predominantly in North America, they have rarely been developed using formative research nor have they been comprehensively evaluated (Saskatchewan Prevention Institute, 2009; Elliott et al., 2008). This lack of published information on the development and evaluation of campaigns makes it difficult to determine what communication elements are most credible …


The Influence Of Set-Repetition Configuration In Eccentric Exercise On Muscle Damage And Repeated Bout Effect, Roy Y.H. Chan Jan 2011

The Influence Of Set-Repetition Configuration In Eccentric Exercise On Muscle Damage And Repeated Bout Effect, Roy Y.H. Chan

Theses: Doctorates and Masters

It is well known that maximal eccentric exercise induces muscle damage, especially when it is performed for the first time. However, muscle damage is attenuated in subsequent bouts of the same or similar exercise, which is known as the repeated bout effect. One of the factors affecting the magnitude of muscle damage and the repeated bout effect is the number of eccentric contractions; however, it is unknown if different set-repetition configurations with the same number of eccentric contractions would result in different magnitudes of muscle damage and adaptation. This study investigated changes in muscle strength, range of motion (ROM), muscle …


The Impact Of Assessment On Repeat Deliberate Self-Harm, Kellie Jones Jan 2011

The Impact Of Assessment On Repeat Deliberate Self-Harm, Kellie Jones

Theses: Doctorates and Masters

Deliberate self-harm is a pervasive issue that is the topic of worldwide clinical and research focus. Among the extensive research findings two salient issues emerge that provide the foundation for this study. The first is that a deliberate self-harm attempt is a significant risk factor for future attempts. The second is that a comprehensive assessment of a person presenting with an incident of deliberate self-harm can reduce further deliberate self-harming behaviour. A limitation of existing research is that no study has clearly identified the nature of assessments that impact on the likelihood of future self-harm attempts. The initial aim of …


Occupational Respiratory Health Surveillance At Minara Resources, Murrin Murrin Mine Site, Martyn Cross Jan 2011

Occupational Respiratory Health Surveillance At Minara Resources, Murrin Murrin Mine Site, Martyn Cross

Theses: Doctorates and Masters

This thesis outlines the results of occupational respiratory health surveillance at Minara Resources, Murrin Murrin mine site. The research was conducted as part of a collaborative agreement between Edith Cowan University and Minara Resources, the overarching title of which was ‗Establishing best practice protocols in the management of occupational and environmental health in a high-risk mining and ore-processing environment‘. To form the basis of this research it was hypothesised that although the chemical hazards had been adequately identified, and the occupational exposures in each work area at Murrin Murrin were generally well below their respective occupational exposure levels, it was …


The Characterisation Of Pax3 Expressant Cells In Adult Peripheral Nerve, Judith A. Blake Jan 2011

The Characterisation Of Pax3 Expressant Cells In Adult Peripheral Nerve, Judith A. Blake

Theses: Doctorates and Masters

Pax3 has numerous integral functions in embryonic tissue morphogenesis while knowledge of its complex function in cells of adult tissue continues to unfold. Across a variety of adult tissue lineages, the role of Pax3 is principally linked to maintenance of the tissue’s resident stem and progenitor cell population. In adult peripheral nerves, Pax3 is reported to be expressed in nonmyelinating Schwann cells, however, little is known about the purpose of this expression. Based on the evidence of its role in other adult tissue stem and progenitor cell maintenance, it was hypothesised that the cells in adult peripheral nerve that express …