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Chulalongkorn University

The Thai Journal of Veterinary Medicine

Vaccine

Articles 1 - 11 of 11

Full-Text Articles in Medicine and Health Sciences

Identification And Characterization Of A Novel Protective Antigen, Sesec_00396 Of Streptococcus Equi Ssp. Zooepidemicus, Li Yi, Weiping Yang, Jinpeng Li, Shaohui Wang, Yang Wang Jun 2021

Identification And Characterization Of A Novel Protective Antigen, Sesec_00396 Of Streptococcus Equi Ssp. Zooepidemicus, Li Yi, Weiping Yang, Jinpeng Li, Shaohui Wang, Yang Wang

The Thai Journal of Veterinary Medicine

Streptococcus equi ssp. zooepidemicus (SEZ) is responsible for a wide variety of infections in many animal species. Studies aimed at developing safe and effective vaccines against SEZ infections are thus of great interest. SeseC_00396 was a novel protein identified in the previous study. In this study, recombinant SeseC_00396 of SEZ was expressed and showed a strong immunoreactivity with mini-pig convalescent sera. Studies in mice have revealed that the recombinant protein induced a marked antibody response which was associated with protection against SEZ infection. The hyperimmune sera against SeseC_00396 could efficiently kill the bacteria. In addition, it was also found that …


Expression Of Mir-29a And Ifn-Γ In Pigs Vaccinated With Modified Live Prrs Vaccine, Sunaree Nantakhruea, Nuntawan Aunjangwang, Orawan Limsivilai, Win Surachetpong Jun 2017

Expression Of Mir-29a And Ifn-Γ In Pigs Vaccinated With Modified Live Prrs Vaccine, Sunaree Nantakhruea, Nuntawan Aunjangwang, Orawan Limsivilai, Win Surachetpong

The Thai Journal of Veterinary Medicine

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the important RNA viruses that affects swine production worldwide. To better improve vaccine efficacy, understanding the molecular mechanisms and viral-host interaction is important to increase the knowledge of vaccine response. The objective of this study was to investigate the expression levels of miR-29a and IFN-γ in pigs that received modified live PRRSV vaccine. The study revealed that both miR-29a and IFN-γ transcript levels increased in vivo early, at day 3 post vaccination, whereas levels of miR-29a and IFN-γ mRNA were not different at day 7 post vaccination. Our study is …


Improved Growth Performance By Type 2 Porcine Reproductive And Respiratory Syndrome Virus (Prrsv)-Based Modified Live Vaccine In A Herd With Concurrent Circulation Of Type 1 And Type 2 Prrsv, Ikjae Kang, Hei Suk Kang, Jiwoon Jeong, Changhoon Park, Seeun Kim, Kyuhyung Choi, Su-Jin Park, Sung-Min Hwang, Beomseok Oh, Sung-Hoon Kim, Byunghak Kang, Chanhee Chae Mar 2017

Improved Growth Performance By Type 2 Porcine Reproductive And Respiratory Syndrome Virus (Prrsv)-Based Modified Live Vaccine In A Herd With Concurrent Circulation Of Type 1 And Type 2 Prrsv, Ikjae Kang, Hei Suk Kang, Jiwoon Jeong, Changhoon Park, Seeun Kim, Kyuhyung Choi, Su-Jin Park, Sung-Min Hwang, Beomseok Oh, Sung-Hoon Kim, Byunghak Kang, Chanhee Chae

The Thai Journal of Veterinary Medicine

The objective of this study was to evaluate type 2 porcine reproductive and respiratory syndrome virus (PRRSV)-based modified live vaccine in a herd with concurrent circulation of type 1 and type 2 PRRSV. Type 2 PRRSV-based modified live vaccine improved average daily gain by 48.24 grams/pig/day (631.17 grams/pig/day in the vaccinated group vs 582.93 grams/pig/day in the unvaccinated group; P < 0.05). Pathological examination indicated that the vaccination effectively reduced microscopic lung lesions compared with the control animals. The protection of this vaccine against type 1 and type 2 PRRSV provides clinical control of co-infection with both genotypes under field conditions.


Efficacy Of Live H120 Strain Against Variant Genotype Infectious Bronchitis Virus Isolated In Thailand In Broiler Chickens, Tawatchai Pohuang, Jiroj Sasipreeyajan Sep 2015

Efficacy Of Live H120 Strain Against Variant Genotype Infectious Bronchitis Virus Isolated In Thailand In Broiler Chickens, Tawatchai Pohuang, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

This study investigated the level of protection generated by vaccination with a live attenuated infectious bronchitis virus (IBV) vaccine, H120 strain against variant genotype IBV isolated in Thailand. Sixty 1-day-old female broiler chickens were randomly divided into 4 groups of 15 chickens each. The chickens in Group 1 were vaccinated at 1 day old, whereas the chickens in Group 2 were vaccinated at 7 days old. Groups 3 and 4 did not receive IBV vaccine and served as positive and negative control groups, respectively. At 21 days of age, the chickens in Groups 1-3 were individually challenged with 104.8 EID50 …


Determination Of Antibody Responses To Mpb83 Antigen In Bcg-Vaccinated Rusa Deer (Rusa Timorensis), Sirinart Chaichanathong, Worawidh Wajjwalku, Chayanid Prasanwong, Melanee Suksamranthaweerat, Piyawan Rasitanon, Aunchisa Phojun, Antja Watanangura, Orawan Boodde, Nikorn Thongtip Dec 2014

Determination Of Antibody Responses To Mpb83 Antigen In Bcg-Vaccinated Rusa Deer (Rusa Timorensis), Sirinart Chaichanathong, Worawidh Wajjwalku, Chayanid Prasanwong, Melanee Suksamranthaweerat, Piyawan Rasitanon, Aunchisa Phojun, Antja Watanangura, Orawan Boodde, Nikorn Thongtip

The Thai Journal of Veterinary Medicine

Bovine tuberculosis (BTB) is a contagious zoonotic disease that causes serious public health concerns. Cervidae are highly susceptible to BTB and it has been diagnosed in various deer species. In order to develop BTB eradication and control program, Mycobacterium bovis Bacille Calmette Guerin (BCG) vaccination has been studied in cervids. In this study 15 rusa deer were tested for responsiveness to mycobacterial reaction using a comparative cervical skin test (CCT). The rusa deer were divided into 2 groups; BCG vaccination group, which were inoculated with a single dose of 2x106 cfu M. bovis BCG Tokyo subcutaneously (n=8) and control group …


Efficacy Of Live Infectious Bronchitis Vaccine Programs Against Infection By Qx-Like Strain Of Infectious Bronchitis Virus, Ekasingh Sarueng, Wisanu Wanasawaeng, Jiroj Sasipreeyajan, Niwat Chansiripornchai Jun 2014

Efficacy Of Live Infectious Bronchitis Vaccine Programs Against Infection By Qx-Like Strain Of Infectious Bronchitis Virus, Ekasingh Sarueng, Wisanu Wanasawaeng, Jiroj Sasipreeyajan, Niwat Chansiripornchai

The Thai Journal of Veterinary Medicine

The aim of this study was to evaluate the efficacy of live infectious bronchitis (IB) vaccine programs against infection by a QX-like strain of the IB virus isolated in Thailand. The experimental groups were divided into 5 groups. Group 1 broilers were administered with Poulvac IB QX-like at 1 day old. Group 2 broilers were administered with Poulvac IB QX-like at 1 and 14 days old. Group 3 broilers were administered with Nobilis IB H120 and Poulvac IB QX-like at 1 and 14 days old, respectively. Group 4 broilers were administered with Nobilis IB H120 and Nobilis IB 4-91 at …


The Effectiveness Of Vaccination With Two Live Infectious Bronchitis Vaccine Strains Against Qx-Like Infectious Bronchitis Virus Isolated In Thailand, Tawatchai Pohuang, Niwat Chansiripornchai, Achara Tawatsin, Jiroj Sasipreeyajan Jun 2014

The Effectiveness Of Vaccination With Two Live Infectious Bronchitis Vaccine Strains Against Qx-Like Infectious Bronchitis Virus Isolated In Thailand, Tawatchai Pohuang, Niwat Chansiripornchai, Achara Tawatsin, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

The purpose of this study was to evaluate the level of protection generated by vaccination with 2 live attenuated vaccine strains against QX-like infectious bronchitis virus (IBV) isolated in Thailand. Eighty-four 1-day-old broiler chickens were randomly allocated into 6 groups with 14 chickens in each group. Groups 1-4 were vaccinated with different vaccination programs against IBV. Groups 5 and 6 did not receive any IBV vaccine and served as positive and negative control groups, respectively. At 1 day old, the chickens in groups 1 and 4 were vaccinated with H120 vaccine whereas the chickens in groups 2 and 3 were …


Efficacy Of Different Vaccination Programs Against Velogenic Newcastle Disease Virus Challenged In 28-Day-Old Broiler Chickens, Tawatchai Pohuang, Nida Sirikobkul, Jiroj Sasipreeyajan Sep 2013

Efficacy Of Different Vaccination Programs Against Velogenic Newcastle Disease Virus Challenged In 28-Day-Old Broiler Chickens, Tawatchai Pohuang, Nida Sirikobkul, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

In the present study, the efficacy of different vaccination programs against a velogenic Newcastle disease virus (vNDV) challenged in 28-day-old broiler chickens was examined. The chickens were divided into 5 groups, 20 chickens in each. Group 1 did not receive any vaccine and served as the non-vaccinated control group. Groups 2-5 were vaccinated with different vaccination programs against vNDV. At 1-day-old, the chickens in all the vaccinated groups were vaccinated with live Newcastle disease (ND) vaccine, Ulster 2C strain, followed by different inactivated vaccines including vaccine A in groups 2 and 4 and vaccine B in groups 3 and 5. …


Efficacy Of Different Vaccination Programs Against Newcastle Disease Virus Challenge In Broiler Chickens, Jiroj Sasipreeyajan, Tawatchai Pohuang, Nida Sirikobkul Dec 2012

Efficacy Of Different Vaccination Programs Against Newcastle Disease Virus Challenge In Broiler Chickens, Jiroj Sasipreeyajan, Tawatchai Pohuang, Nida Sirikobkul

The Thai Journal of Veterinary Medicine

The present study was designed to determine the protection afforded by different vaccination programs against the virulent Newcastle disease virus (vNDV). The chickens were divided into 7 groups, 40 chickens in each. Group 1 did not receive any vaccine and served as a negative control group. Groups 2-7 were vaccinated with different vaccination programs against vNDV. At 1 day old, the chickens in all the vaccinated groups were inoculated with live attenuated vaccine, Ulster strain, followed by different inactivated vaccines including 0.1 ml/chicken of inactivated vaccine A in groups 2 and 4, 0.1 ml/chicken of inactivated vaccine B in groups …


Efficacy Of Different Vaccination Programs Against Thai Qx-Like Infectious Bronchitis Virus, Jiroj Sasipreeyajan, Tawatchai Pohuang, Nida Sirikobkul Mar 2012

Efficacy Of Different Vaccination Programs Against Thai Qx-Like Infectious Bronchitis Virus, Jiroj Sasipreeyajan, Tawatchai Pohuang, Nida Sirikobkul

The Thai Journal of Veterinary Medicine

The present study was designed to evaluate the protection induced by different vaccination programs against Thai QX-like infectious bronchitis virus (IBV). The chickens were divided into 5 groups, 16 chickens in each. Groups 1-4 were vaccinated with different regimes of vaccination program against IBV. Groups 5 did not receive IBV vaccine and served as a positive control group. At 1 day old, the chickens in groups 2 and 3 were vaccinated with QX vaccine whereas the chickens in group 4 were vaccinated with H120 vaccine. At 14 days old, revaccination was performed in group 2 with QX vaccine whereas groups …


Efficacy Of Various Strains Of Infectious Bronchitis Vaccine Against Nephropathogenic Infectious Bronchitis Virus Isolated From Chickens In Thailand, Tawatchai Pohuang, Kanlaya Chuachan, Niwat Chansiripornchai, Jiroj Sasipreeyajan Dec 2009

Efficacy Of Various Strains Of Infectious Bronchitis Vaccine Against Nephropathogenic Infectious Bronchitis Virus Isolated From Chickens In Thailand, Tawatchai Pohuang, Kanlaya Chuachan, Niwat Chansiripornchai, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

One hundred, 1 week old, female broiler chickens were divided into 5 groups, 20 chickens in each. Each group was vaccinated with a different strain of infectious bronchitis vaccine; Ma5, H120 and a local strain produced by the Department of Livestock Development for groups 3, 4 and 5, respectively. All the vaccinated chickens received intraocular vaccine at 1 week old. The chickens in groups 1 and 2 served as a negative control and a positive control group, respectively. All the chickens were weighed at 1, 4 and 6 weeks old and challenged at 4 weeks old with nephropathogenic infectious bronchitis …