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Chulalongkorn University

The Thai Journal of Veterinary Medicine

Efficacy

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Full-Text Articles in Medicine and Health Sciences

Efficacy Of Immune Complex Infectious Bursal Disease Vaccines Against Very Virulent Infectious Bursal Disease Virus Challenge In Commercial Layer Chicken, Nataya Charoenvisal, Phornphisut Areeraksakul, Choew Kong Mah, Nida Sirikobkul, Nida Sirikobkul Sep 2022

Efficacy Of Immune Complex Infectious Bursal Disease Vaccines Against Very Virulent Infectious Bursal Disease Virus Challenge In Commercial Layer Chicken, Nataya Charoenvisal, Phornphisut Areeraksakul, Choew Kong Mah, Nida Sirikobkul, Nida Sirikobkul

The Thai Journal of Veterinary Medicine

The vaccination program for controlling Infectious bursal disease (IBD) was complicated due to high maternal antibody in day old chick. Therefore, our study was performed in young layer chickens with high maternal antibody as commonly seen in our country. The objective of this study was to determine the protective efficacy of immune complex IBD vaccines against very virulent infectious bursal disease virus (vvIBDV) challenge in commercial layer chickens. As immune complex vaccine A was recommended in layers by the company, the first aim of the study was to compare immune complex vaccine A (group 1) and B (group 3). The …


Efficacy Of Different Vaccination Programs Of Recombinant Hvt-Ndv Vaccine Against Genotype Vii Ndv Challenge In Broiler Chickens, Nataya Charoenvisal, Bubpa Supannamoke, Rik Koopman, Jiroj Sasipreeyajan Dec 2018

Efficacy Of Different Vaccination Programs Of Recombinant Hvt-Ndv Vaccine Against Genotype Vii Ndv Challenge In Broiler Chickens, Nataya Charoenvisal, Bubpa Supannamoke, Rik Koopman, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

This study determined the efficacy of recombinant HVT- NDV ( rHVT- NDV) vaccine simultaneously vaccinated with live vaccine at 1 day old and a booster vaccination with live vaccine at 10 days old against Asiatic, Genotype VII NDV in broiler chickens. The chickens were divided into 5 groups. The chickens in groups 1, 2 and 3 were vaccinated with rHVT- NDV vaccine and different live vaccines at 1 day old, and then finally received a booster vaccination at 10 days old. The chickens in groups 4 and 5 served as the positive and negative control groups, respectively. The chickens in …


A Rabbit Model For Evaluating The Efficacy Of Recombinant Adenovirus Vaccine Expressing E0-E2 Antigens Of Classical Swine Fever Virus, Heng Zhang, Yong-Ke Sun, Xiao-Miao Zhang, Hui Zhang, Gen-Cheng Fan, Yu-Lin Yan, Yu-Ai Yang Sep 2017

A Rabbit Model For Evaluating The Efficacy Of Recombinant Adenovirus Vaccine Expressing E0-E2 Antigens Of Classical Swine Fever Virus, Heng Zhang, Yong-Ke Sun, Xiao-Miao Zhang, Hui Zhang, Gen-Cheng Fan, Yu-Lin Yan, Yu-Ai Yang

The Thai Journal of Veterinary Medicine

This study investigated the efficacy of a recombinant adenovirus vaccine expressing E0-E2 antigens (rAd-E0-E2) of the classical swine fever virus (CSFV) and determined its minimum effective dose in rabbits. Forty rabbits were randomly divided into five groups. Three groups were immunized intramuscularly with rAd-E0-E2 at doses of 107.0, 106.0 and 105.0 IFU, respectively. CSFV C strain was administered to one group and saline to another group (negative control). Fourteen days after immunization, the animals were challenged intramuscularly with CSFV C strain. Stereotypical thermal responses were monitored to assess the protective efficacy of the vaccine. No typical thermal response was observed …


Efficacy Of Different Vaccination Programs Of Live 4/91 Strain Against Thai Qx-Like Infectious Bronchitis Virus In Broiler Chickens, Tawatchai Pohuang, Sarawut Tanasatian, Jiroj Sasipreeyajan Sep 2016

Efficacy Of Different Vaccination Programs Of Live 4/91 Strain Against Thai Qx-Like Infectious Bronchitis Virus In Broiler Chickens, Tawatchai Pohuang, Sarawut Tanasatian, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

Thai QX-like infectious bronchitis virus (IBV) has caused problems in commercial chicken farms as well as small farms in many parts of Thailand. This study investigated the level of protection generated by vaccination with different IBV vaccination programs, 4/91 strain against Thai QX-like IBV. One hundred 1 day old female broiler chickens were randomly divided into 5 groups of 20 chickens each. The chickens in Group 1 were vaccinated with Ma5 strain IBV vaccine at 1 day old and with 4/91 strain IBV vaccine at 14 days old. The chickens in Group 2 were vaccinated with Ma5 and simultaneously with …


Protective Efficacy Of Live Lasota Strain Newcastle Disease Virus Vaccine In Layer-Type Chickens, Jiroj Sasipreeyajan, Phornphisut Areeraksakul, Somkid Khanda Jun 2016

Protective Efficacy Of Live Lasota Strain Newcastle Disease Virus Vaccine In Layer-Type Chickens, Jiroj Sasipreeyajan, Phornphisut Areeraksakul, Somkid Khanda

The Thai Journal of Veterinary Medicine

The purpose of this study was to evaluate the protective efficacy of live LaSota strain Newcastle disease virus (NDV) vaccine administered with different routes against a NDV challenge in layer-type chickens. Fifty male layer-type chickens were divided into 3 groups. There were 20 chickens/group for the vaccinated groups (Groups 1 and 2) and 10 chickens for the non-vaccinated control group (Group 3). Chickens in Groups 1 and 2 received the vaccine individually at 4 weeks old by eye drop and oral drop, respectively. All chickens received NDV challenge individually by oral drop at 7 weeks old or 3 weeks post-vaccination …


Efficacy Of Live H120 Strain Against Variant Genotype Infectious Bronchitis Virus Isolated In Thailand In Broiler Chickens, Tawatchai Pohuang, Jiroj Sasipreeyajan Sep 2015

Efficacy Of Live H120 Strain Against Variant Genotype Infectious Bronchitis Virus Isolated In Thailand In Broiler Chickens, Tawatchai Pohuang, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

This study investigated the level of protection generated by vaccination with a live attenuated infectious bronchitis virus (IBV) vaccine, H120 strain against variant genotype IBV isolated in Thailand. Sixty 1-day-old female broiler chickens were randomly divided into 4 groups of 15 chickens each. The chickens in Group 1 were vaccinated at 1 day old, whereas the chickens in Group 2 were vaccinated at 7 days old. Groups 3 and 4 did not receive IBV vaccine and served as positive and negative control groups, respectively. At 21 days of age, the chickens in Groups 1-3 were individually challenged with 104.8 EID50 …


Efficacy Of Live Infectious Bronchitis Vaccine Programs Against Infection By Qx-Like Strain Of Infectious Bronchitis Virus, Ekasingh Sarueng, Wisanu Wanasawaeng, Jiroj Sasipreeyajan, Niwat Chansiripornchai Jun 2014

Efficacy Of Live Infectious Bronchitis Vaccine Programs Against Infection By Qx-Like Strain Of Infectious Bronchitis Virus, Ekasingh Sarueng, Wisanu Wanasawaeng, Jiroj Sasipreeyajan, Niwat Chansiripornchai

The Thai Journal of Veterinary Medicine

The aim of this study was to evaluate the efficacy of live infectious bronchitis (IB) vaccine programs against infection by a QX-like strain of the IB virus isolated in Thailand. The experimental groups were divided into 5 groups. Group 1 broilers were administered with Poulvac IB QX-like at 1 day old. Group 2 broilers were administered with Poulvac IB QX-like at 1 and 14 days old. Group 3 broilers were administered with Nobilis IB H120 and Poulvac IB QX-like at 1 and 14 days old, respectively. Group 4 broilers were administered with Nobilis IB H120 and Nobilis IB 4-91 at …


Efficacy Of Fenbendazole Against Ascaridia Spp. In Large Macaws, Thawat Lekdumrongsak, Sonthaya Tiawsirisup, Wijit Banlunara, Funknathee Prapasawat, Monchanok Pussayanawin, Nicha Prommatha, Suttipong Suttiyaporn Jun 2014

Efficacy Of Fenbendazole Against Ascaridia Spp. In Large Macaws, Thawat Lekdumrongsak, Sonthaya Tiawsirisup, Wijit Banlunara, Funknathee Prapasawat, Monchanok Pussayanawin, Nicha Prommatha, Suttipong Suttiyaporn

The Thai Journal of Veterinary Medicine

Ascarids are common endoparasites in psittacines. Fenbendazole has been reported for treatment of ascarid infection in many avian species. In this study, the efficacy of fenbendazole against Ascaridia spp. in large macaws was evaluated. Seventeen pairs of naturally infected large macaws were divided into 3 groups. Birds in group 1 (6 pairs) were treated with fenbendazole per os at 35 mg/kg and repeatedly on day 10. Birds in group 2 (5 pairs) were treated with fenbendazole mixed in feed at 35 mg/kg and repeatedly on day 10. Birds in group 3 (6 pairs) served as untreated control group. Ascarid eggs …


Efficacy And Safety Of Different Live Mycoplasma Gallisepticum Vaccines In Layer Chickens, Somsak Pakpinyo, Suwarak Wanaratana, Kreangkrai Sangthongdang, Marcelo Paniago Dec 2013

Efficacy And Safety Of Different Live Mycoplasma Gallisepticum Vaccines In Layer Chickens, Somsak Pakpinyo, Suwarak Wanaratana, Kreangkrai Sangthongdang, Marcelo Paniago

The Thai Journal of Veterinary Medicine

The efficacy and safety of different live Mycoplasma gallisepticum (MG) vaccines were determined. One hundred and fifty six-week-old female layer chickens were equally divided into 6 groups. Groups 1-6 received F (two groups), 6/85 and ts-11 strains, positive and negative control, respectively. At 8 weeks old, 5 birds/group were sacrificed and gross thoracic airsac lesion scores (GTALS) and microscopic tracheal lesion scores (MTLS) were blindly evaluated. At 12 weeks old, groups 1-5 were challenged through an eye dropping with approximately 1x106 CFU of MG Thai isolated. At 13 and 14 weeks old, 10 birds/group were swabbed in the palatine fissure …


Efficacy Of Different Vaccination Programs Against Velogenic Newcastle Disease Virus Challenged In 28-Day-Old Broiler Chickens, Tawatchai Pohuang, Nida Sirikobkul, Jiroj Sasipreeyajan Sep 2013

Efficacy Of Different Vaccination Programs Against Velogenic Newcastle Disease Virus Challenged In 28-Day-Old Broiler Chickens, Tawatchai Pohuang, Nida Sirikobkul, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

In the present study, the efficacy of different vaccination programs against a velogenic Newcastle disease virus (vNDV) challenged in 28-day-old broiler chickens was examined. The chickens were divided into 5 groups, 20 chickens in each. Group 1 did not receive any vaccine and served as the non-vaccinated control group. Groups 2-5 were vaccinated with different vaccination programs against vNDV. At 1-day-old, the chickens in all the vaccinated groups were vaccinated with live Newcastle disease (ND) vaccine, Ulster 2C strain, followed by different inactivated vaccines including vaccine A in groups 2 and 4 and vaccine B in groups 3 and 5. …


Antiparasitic Efficacy Of 10% W/V Fipronil Spot-On (Fiproline Spot-On) Against Experimental Tick (Rhipicephalus Sanguineus) Infestations On Dogs, Sonthaya Tiawsirisup, Kanokwan Thiansirikhun, Kanoksak Thanadumkerng, Nuttika Pastarapatee, Nunaree Trirattananuwong, Wilai Rattanatayarom Jun 2013

Antiparasitic Efficacy Of 10% W/V Fipronil Spot-On (Fiproline Spot-On) Against Experimental Tick (Rhipicephalus Sanguineus) Infestations On Dogs, Sonthaya Tiawsirisup, Kanokwan Thiansirikhun, Kanoksak Thanadumkerng, Nuttika Pastarapatee, Nunaree Trirattananuwong, Wilai Rattanatayarom

The Thai Journal of Veterinary Medicine

This study was conducted to investigate the efficacy of 10% w/v fipronil spot-on for treatment and prevention of Rhipicephalus sanguineus infestations on dogs. Twelve Beagles were randomly separated into two groups which were treatment and control group (6 dogs/group). The treatment group received 10% fipronil spot-on at the dosage of 6.7 mg/kg on day 0. A group of 60 Rhipicephalus sanguineus was released to feed on each dog on day -7, -2, 7, 14, 21, and 28. The ticks were counted and removed on days-4, 3, 10, 17, 24, and 31. Mean number of tick infestations in the control group …


Clinical Study On The Treatment Of Piroline Against Bovine Mastitis, Jian-Ping Liang, Bao-Cheng Hao, Xue-Hong Wang, Zhi-Ting Guo, Wen-Zhu Guo, Ruo-Feng Shang, Lei Tao, Yu Liu, Zhao-Zhou Li, Lan-Ying Hua, Shu-Yang Wang Mar 2011

Clinical Study On The Treatment Of Piroline Against Bovine Mastitis, Jian-Ping Liang, Bao-Cheng Hao, Xue-Hong Wang, Zhi-Ting Guo, Wen-Zhu Guo, Ruo-Feng Shang, Lei Tao, Yu Liu, Zhao-Zhou Li, Lan-Ying Hua, Shu-Yang Wang

The Thai Journal of Veterinary Medicine

The study aims to investigate the efficacy of piroline and antibiotics in the treatment of bovine mastitiscaused by Streptococcus uberis (S. uberis) and Escherichia coli (E. coli) during dry-milk period. 1880 cows in dry-milkperiod were divided into 4 groups and treated with penicillin G, ammonia benzyl penicillin, ceftiofur and piroline,respectively. The efficacy of each medicine in treating mastitis caused by E. coli intramammary infection (E. coli IMI)was followed: 31.2% for penicillin G, 36.9% for ammonia benzyl penicillin, 61.3% for ceftiofur, and 64.4% for Piroline.For those caused by S. uberis intramammary infection (S. uberis IMI), the efficacy of ceftiofur was 90% …


Efficacy Of A Chimeric Pcv2 Vaccine: A Field Trial, Termsitthi Paphavasit, Philip Lehrbach, Wichian Navasakuljinda, Roongtham Kedkovid, Sitthichok Lacharoje, Roongroje Thanawongnuwech, Komkrich Teankum Jun 2009

Efficacy Of A Chimeric Pcv2 Vaccine: A Field Trial, Termsitthi Paphavasit, Philip Lehrbach, Wichian Navasakuljinda, Roongtham Kedkovid, Sitthichok Lacharoje, Roongroje Thanawongnuwech, Komkrich Teankum

The Thai Journal of Veterinary Medicine

Field trial of a Chimeric porcine circovirus type 2 (PCV2) (Suvaxyn PCV2®, Fort Dodge Animal Health, USA) vaccine was performed in order to investigate the efficacy on decreasing pathological lesions and PCV2 viremia in a PCV2-affected swine herd in Thailand. A herd was selected based on history and serological data. Three-week-old pigs (n = 200) were equally divided into two groups. At 4 weeks old, the pigs (n = 100) were injected intramuscularly with 2 ml of Suvaxyn PCV2® vaccine and the non-vaccinated pigs were injected with 2 ml of normal saline. Sera were collected from 20 pigs per group …


The Efficacy Of Ivermectin (Ivomec®) Against Gastrointestinal Nematodes Of Sheep In Thailand, Vanni Chaisanabunthid, Kanchana Kengkoom, Wantanee Ratanasak, Darunee Buripakdi Lawson Sep 2003

The Efficacy Of Ivermectin (Ivomec®) Against Gastrointestinal Nematodes Of Sheep In Thailand, Vanni Chaisanabunthid, Kanchana Kengkoom, Wantanee Ratanasak, Darunee Buripakdi Lawson

The Thai Journal of Veterinary Medicine

Rectal, faecal samples from 14 sheep were collected 3 times a day (morning, noon and evening) and examined for nematode eggs by the formalin-ether, sedimentation technique and the Brine floatation technique. The faecal egg counts were done by using the Stoll’s dilution, egg counting technique. The sheep were injected with ivermectin (Ivomec®) (0.2 mg/kg) subcutaneously. Three weeks later, faecal samples were collected and examined to determine the outcome of the treatment. It was found that strongyles and Trichuris ovis eggs were absent. It was concluded that Ivomec® showed good efficacy for the treatment of some gastrointestinal nematodes in this study …


Evaluation Of The Efficacy Of Dl-Methionine And Methoonine Hydroxy Analogue In Broiler Diets, S. Kijparkorn, A. Suriyasomboon, C. Nuengjamnong Dec 1997

Evaluation Of The Efficacy Of Dl-Methionine And Methoonine Hydroxy Analogue In Broiler Diets, S. Kijparkorn, A. Suriyasomboon, C. Nuengjamnong

The Thai Journal of Veterinary Medicine

Nine hundred and sixty day-old chicks of both sexes were divided into 24 groups of 40 birds each and fed for 42 days. Diets were prepared and fed over two phases (1-21 and 22-42 days of age). They were calculated to be deficient either in methionine and sulfur amino acids (negative control diet) or supplemented with 0.24% DL-Methionine (DL-M) or 0.37% Methionine Hydroxy Analogue (MHA). Weight gain and feed intake were calculated so that an evaluation of the efficacy of the 2 sources of methionine could be made. A significant response (P<0.05) in the average weight gain over negative controls (0.55+0.01 kg/bird) was found for DL-M supplemented diets (0.59± 0.01 kg/bird) in phase I, whereas MHA (0.57±0.01kg/bird) did not show any improvement. The feed conversion ratio of DL-M (1.80±0.03) and MHA (1.82±0.04) was significantly different to the negative control (1.93±0.03). There were no significant differences in all performances during phase II. The overall results showed that broilers fed with 0.24% DL-Methionine or 0.37% Methionine Hydroxy Analogue fortified rations showed the same growth rates. It may be concluded that MHA was 65% as efficient as DL-methionine in broiler chicks during the 1-21 day old period of their lives.