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Bond University

Selected Works

Evidence-Based Medicine

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Full-Text Articles in Medicine and Health Sciences

Taking Healthcare Interventions From Trial To Practice, Paul Glasziou, Iain Chalmers, Douglas Altman, Hilda Bastian, Isabelle Boutron, Anne Brice, Gro Jamtvedt, Andrew Farmer, Davina Ghersi, Trish Groves, Carl Heneghan, Sophie Hill, Simon Lewin, Susan Michie, Rafael Perera, Valerie Pomeroy, Julie Tilson, Sasha Shepperd, John Williams Aug 2010

Taking Healthcare Interventions From Trial To Practice, Paul Glasziou, Iain Chalmers, Douglas Altman, Hilda Bastian, Isabelle Boutron, Anne Brice, Gro Jamtvedt, Andrew Farmer, Davina Ghersi, Trish Groves, Carl Heneghan, Sophie Hill, Simon Lewin, Susan Michie, Rafael Perera, Valerie Pomeroy, Julie Tilson, Sasha Shepperd, John Williams

Paul Glasziou

Extract:
The results of thousands of trials are never acted on because their published reports do not describe the interventions in enough detail. How can we improve the reporting?

Much healthcare research is currently wasted because its findings are unusable.¹ Published reports of intervention trials often focus on the results and fail to describe interventions adequately. For example, a review of 80 studies selected for the journal Evidence Based Medicine as both valid and important for clinical practice found that clinicians could replicate the intervention in only half the studies.² Interventions may be used incorrectly or not at all if …


Tonsillectomy Or Adeno-Tonsillectomy Versus Non-Surgical Treatment For Chronic/Recurrent Acute Tonsillitis (Review), Martin Burton, Paul Glasziou Jan 2009

Tonsillectomy Or Adeno-Tonsillectomy Versus Non-Surgical Treatment For Chronic/Recurrent Acute Tonsillitis (Review), Martin Burton, Paul Glasziou

Paul Glasziou

Background: Surgical removal of the tonsils, with or without adenoidectomy (adeno-/tonsillectomy), is a common ENT operation but the indications for surgery are controversial.

Objectives: To determine the effects of tonsillectomy, with and without adenoidectomy, in patients with chronic/recurrent acute tonsillitis. Search methods: The Cochrane Ear, Nose and Throat Disorders Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2008, issue 2), MEDLINE (1966 to 2008), EMBASE (1974 to 2008), bibliographies, and additional sources were searched for published and unpublished trials. The date of the last search was 11 April 2008.

Selection criteria: Randomised controlled …