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Full-Text Articles in Medicine and Health Sciences

Managing Data For The International, Multicentre Intergrowth-21st Project, E O. Ohuma, L Hoch, C Cosgrove, H E. Knight, L Cheikh Ismail, L Juodvirsiene, A T. Papageorghiou, H Al-Jabri, M Domingues, P Gilli, N Kunnawar, N Musee, F Roseman, A Carter, M Wu, D G. Altman Sep 2013

Managing Data For The International, Multicentre Intergrowth-21st Project, E O. Ohuma, L Hoch, C Cosgrove, H E. Knight, L Cheikh Ismail, L Juodvirsiene, A T. Papageorghiou, H Al-Jabri, M Domingues, P Gilli, N Kunnawar, N Musee, F Roseman, A Carter, M Wu, D G. Altman

Obstetrics and Gynaecology, East Africa

The INTERGROWTH-21st Project data management was structured incorporating both a centralised and decentralised system for the eight study centres, which all used the same database and standardised data collection instruments, manuals and processes. Each centre was responsible for the entry and validation of their country-specific data, which were entered onto a centralised system maintained by the Data Coordinating Unit in Oxford. A comprehensive data management system was designed to handle the very large volumes of data. It contained internal validations to prevent incorrect and inconsistent values being captured, and allowed online data entry by local Data Management Units, as well …


Ultrasound Methodology Used To Construct The Fetal Growth Standards In The Intergrowth-21st Project, Papageorghiou A. T, Sarris I, Oannou C I, Todros T, Maria Carvalho, Pilu G, Salomon L. J Sep 2013

Ultrasound Methodology Used To Construct The Fetal Growth Standards In The Intergrowth-21st Project, Papageorghiou A. T, Sarris I, Oannou C I, Todros T, Maria Carvalho, Pilu G, Salomon L. J

Imaging & Diagnostic Radiology, East Africa

A unified protocol is essential to ensure that fetal ultrasound measurements taken in multicentre research studies are accurate and reproducible. This paper describes the methodology used to take two-dimensional, ultrasound measurements in the longitudinal, fetal growth component of the INTERGROWTH-21st Project. These standardised methods should minimise the systematic errors associated with pooling data from different study sites. They represent a model for carrying out similar research studies in the future.


Implementation Of The Intergrowth-21st Project In Kenya, Maria Carvalho, Sudhir Vinayak, Roseline Ochieng, V Choksey, N Musee, W Stones, H E. Knight, L Cheikh Ismail May 2013

Implementation Of The Intergrowth-21st Project In Kenya, Maria Carvalho, Sudhir Vinayak, Roseline Ochieng, V Choksey, N Musee, W Stones, H E. Knight, L Cheikh Ismail

Obstetrics and Gynaecology, East Africa

The African site in the INTERGROWTH-21(st) Project was Parklands, a wealthy suburb of Nairobi, Kenya, with a largely middle-to-high socio-economic status population. There are three hospitals with obstetric units in Parklands, with approximately 4300 births per year. The Newborn Cross-Sectional Study (NCSS) sample was drawn from all three hospitals, covering 100% of births in this target population. The Fetal Growth Longitudinal Study (FGLS) sample was recruited from antenatal clinics serving these hospitals, using the eligibility criteria in the INTERGROWTH-21(st) protocol. Special activities to raise awareness of the study included securing media coverage and distributing leaflets in antenatal clinic waiting rooms. …