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Full-Text Articles in Medicine and Health Sciences

Soothing The Threatened Brain: Leveraging Contact Comfort With Emotionally Focused Therapy, Susan M. Johnson, Melissa Burgess Moser, Lane Beckes, Andra Smith, Rebecca Halchuk, Karen Hasselmo, Paul S. Greenman, Zul Merali, James A. Coan Nov 2013

Soothing The Threatened Brain: Leveraging Contact Comfort With Emotionally Focused Therapy, Susan M. Johnson, Melissa Burgess Moser, Lane Beckes, Andra Smith, Rebecca Halchuk, Karen Hasselmo, Paul S. Greenman, Zul Merali, James A. Coan

Brain and Mind Institute

Social relationships are tightly linked to health and well-being. Recent work suggests that social relationships can even serve vital emotion regulation functions by minimizing threat-related neural activity. But relationship distress remains a significant public health problem in North America and elsewhere. A promising approach to helping couples both resolve relationship distress and nurture effective interpersonal functioning is Emotionally Focused Therapy for couples (EFT), a manualized, empirically supported therapy that is strongly focused on repairing adult attachment bonds. We sought to examine a neural index of social emotion regulation as a potential mediator of the effects of EFT. Specifically, we examined …


Stress And Eating: A Dual Role For Bombesin-Like Peptides, Zul Merali, S. Graitson, J. C. Mackay, P. Kent Oct 2013

Stress And Eating: A Dual Role For Bombesin-Like Peptides, Zul Merali, S. Graitson, J. C. Mackay, P. Kent

Brain and Mind Institute

The current obesity "epidemic" in the developed world is a major health concern; over half of adult Canadians are now classified as overweight or obese. Although the reasons for high obesity rates remain unknown, an important factor appears to be the role stressors play in overconsumption of food and weight gain. In this context, increased stressor exposure and/or perceived stress may influence eating behavior and food choices. Stress-induced anorexia is often noted in rats exposed to chronic stress (e.g., repeated restraint) and access to standard Chow diet; associated reduced consumption and weight loss. However, if a similar stressor exposure takes …


Histology And Ultrastructure Of Transitional Changes In Skin Morphology In The Juvenile And Adult Four-Striped Mouse (Rhabdomys Pumilio), Eranée Stewart, Moyosore Salihu Ajao, Amadi O. Ihunwo Jan 2013

Histology And Ultrastructure Of Transitional Changes In Skin Morphology In The Juvenile And Adult Four-Striped Mouse (Rhabdomys Pumilio), Eranée Stewart, Moyosore Salihu Ajao, Amadi O. Ihunwo

Brain and Mind Institute

The four-striped mouse has a grey to brown coloured coat with four characteristic dark stripes interspersed with three lighter stripes running along its back. The histological differences in the skin of the juvenile and adult mouse were investigated by Haematoxylin and Eosin and Masson Trichrome staining, while melanocytes in the skin were studied through melanin-specific Ferro-ferricyanide staining. The ultrastructure of the juvenile skin, hair follicles, and melanocytes was also explored. In both the juvenile and adult four-striped mouse, pigment-containing cells were observed in the dermis and were homogeneously dispersed throughout this layer. Apart from these cells, the histology of the …