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Medicine and Health Sciences Commons

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Aga Khan University

Section of Gastroenterology

2004

Articles 1 - 3 of 3

Full-Text Articles in Medicine and Health Sciences

Thymosin Alpha 1 In Combination With Interferon Alpha And Ribavirin In Chronic Hepatitis C Patients Who Are Non-Responders Or Relapsers To Interferon Alpha Plus Ribavirin, Z Abbas, S S. Hamid, S Tabassum, W Jafri Nov 2004

Thymosin Alpha 1 In Combination With Interferon Alpha And Ribavirin In Chronic Hepatitis C Patients Who Are Non-Responders Or Relapsers To Interferon Alpha Plus Ribavirin, Z Abbas, S S. Hamid, S Tabassum, W Jafri

Section of Gastroenterology

Objective: Interferon alpha (IFN-alpha) with or without ribavirin is an approved therapy for patients with chronic hepatitis C. However, a sustained response is achieved in less than 40% of all treated cases. Retreatment of relapsers or non-responders usually fails. Thymosin alpha 1 (Ta-1) is a polypeptide with immunomodulatory properties that has been suggested to increase response rates in patients with chronic hepatitis C. The aim of present study was to evaluate the efficacy of a novel triple regimen which includes Ta-1 for relapsers and non-responders to the combination of TA-1 and ribavirin.Methods: In the present study, 11 patients who relapsed …


Irritable Bowel Syndrome: In Search Of An Etiology: Role Of Blastocystis Hominis., Javed Yakoob, Wasim Jafri, Nadim Jafri, Rustam Khan, Muhammad Islam, M. Asim Beg, Viqar Zaman Apr 2004

Irritable Bowel Syndrome: In Search Of An Etiology: Role Of Blastocystis Hominis., Javed Yakoob, Wasim Jafri, Nadim Jafri, Rustam Khan, Muhammad Islam, M. Asim Beg, Viqar Zaman

Section of Gastroenterology

This study was designed to examine stool specimens of irritable bowel syndrome (IBS) patients for Blastocystis hominis, a common intestinal parasite. One hundred fifty patients were enrolled, 95 IBS cases and 55 controls. These patients provided a medical history, and underwent physical and laboratory evaluations that included stool microscopy and culture for B. hominis and colonoscopy. The 95 cases (51 males and 44 females) had a mean +/- SD age of 37.8 +/- 13.2 years. Stool microscopy was positive for B. hominis in 32% (30 of 95) of the cases and 7% (4 of 55) of the controls (P = …


Esophageal Cancer--A Review, A Alidina, T Siddiqui, I Burney, W Jafri, F Hussain, M Ahmed Mar 2004

Esophageal Cancer--A Review, A Alidina, T Siddiqui, I Burney, W Jafri, F Hussain, M Ahmed

Section of Gastroenterology

No abstract provided.