Medicine and Health Sciences Commons^™

Medical Therapy Vs Early Revascularization In Diabetics With Chronic Total Occlusions: A Meta-Analysis And Systematic Review, Muhammad Shayan Khan, Farhad Sami, Hemindermeet Singh, Waqas Ullah, Ma'en Al-Dabbas, Khalid Hamid Changal, Tanveer Mir, Zain Ali, Ameer Kabour

Abington Jefferson Health Papers

BACKGROUND: Management of chronic total occlusions (CTO) in diabetics is challenging, with a recent trend towards early revascularization [ER: Percutaneous coronary intervention (PCI) and bypass grafting] instead of optimal medical therapy (OMT). We hypothesize that ER improves morbidity and mortality outcomes in diabetic patients with CTOs as compared to OMT.

AIM: To determine the long term clinical outcomes and to compare morbidity and mortality between OMT and ER in diabetic patients with CTOs.

METHODS: Potentially relevant published clinical trials were identified in Medline, Embase, chemical abstracts and Biosis (from start of the databases till date) and pooled hazard ratios (HR) …

Implementation And Sustainment Of A Statewide Telemedicine Diabetic Retinopathy Screening Network For Federally Designated Safety-Net Clinics, Ana Bastos De Carvalho, S. Lee Ware, Feitong Lei, Heather M. Bush, Robert Sprang, Eric B. Higgins

Ophthalmology and Visual Science Faculty Publications

CONTEXT: Diabetic retinopathy (DR) is the leading cause of incident blindness among working-age adults in the United States. Federally designated safety-net clinics (FDSC) often serve as point-of-contact for patients least likely to receive recommended DR screenings, creating opportunity for targeted interventions to increase screening access and compliance.

STUDY DESIGN AND METHODS: With such a goal, we implemented and assessed the longitudinal performance of an FDSC-based telemedicine DR screening (TDRS) network of 22 clinical sites providing nonmydriatic fundus photography with remote interpretation and reporting. Retrospective analysis of patient encounters between February 2014 and January 2019 was performed to assess rates of …

A Comparative Study Of Coronary Risk Factors Between Urban And Rural Diabetics In Gaza Strip, Akram Al-Taher

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Background: Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Higher risk of coronary heart disease (CHD) is seen in DM patients who smoke, have lipid abnormalities and hypertension and are obese.
Aim: The aim of this study is to compare the lipid profile levels and other CHD risk factors among DM patients in an urban region (Gaza governorate) with those of the rural region (the eastern region of Khanyounis Governorate) of Gaza Strip. Methods: The study is cross-sectional and included 200 DM patients, aged 10-65 years, whose diabetes …

Diabetes Mellitus Does Not Predict Discharge In Hospitalized Patients With Acute Pyelonephritis: A Study From Karachi, Pakistan, Syed Furrukh Omair, Fazal Ur Rehman, Imrana Amin, Syed Ahsan Ali, Bakhtawar J. Rind, Bilal Ahmed

Section of Nephrology

Introduction: The incidence of acute pyelonephritis (APN) in the diabetic population is comparatively higher and tends to be more complicated, with serious outcomes. Although complicated pyelonephritis (PN) needs hospital admission and intravenous antibiotics, the magnitude of hospital stay due to comorbidities is limited. This study's aim was to assess the impact of diabetes mellitus on length of hospital stay among patients with PN.
Methods: We did a retrospective data review of 520 randomly selected hospitalized patients of PN from March 2015 to December 2019 from a tertiary care center. Electronic medical records were used for identifying medical conditions through ICD-10 …

Study Of Effect Of Glycemic Gap On Adverse Outcomes In Critically Ill Patients With Diabetes, Adel A. S. El Eslam, Sanaa S. Gazareen, Shimaa K. Zewain

Menoufia Medical Journal

Objective To study if higher levels of glycemic gap can be used as a tool to predict adverse outcomes in patients with diabetes mellitus admitted with critical illness. Background The glycemic gap is calculated as a difference between the A1C-derived average glucose and the admission glucose and may be a better reflector of outcomes. Patients and methods This study was conducted on 150 patients with type 2 diabetes mellitus who were admitted to the ICUs of Menoufia University Hospitals and Benha Teaching Hospital. Full detailed history, Simplified Acute Physiologic Score II, Sequential Organ Failure Assessment, Acute Physiology and Chronic Health …

The Association Between Osteoporosis And Diabetic Neuropathy In Patients With Type 2 Diabetes, Hytham R. Badr, Mohammad G. Alhelbawy, Mostafa M. El-Najjar, Nabil A. El-Kafrawy, Walid A. Shehab Eldin

Menoufia Medical Journal

Objective The objective of this study was to evaluate the association between osteoporosis and diabetic peripheral neuropathy in patients with type 2 diabetes mellitus (T2DM). Background Diabetic complications and osteoporotic fractures are two of the most important causes of morbidity and mortality in older patients. There is increased fracture rate associated with T2DM, despite these patients having greater bone mineral density. Osteocalcin, one of the bone turnover markers, is a peptide secreted by bone cells and reflects bone formation and consequently indicates bone remodeling status; which is the major mechanism underlying osteoporosis. Patients and methods This case–control study was done …

Serum Adiponectin Level In Osteoporotic Postmenopausal Women With Type 2 Diabetes Mellitus, Mohammed A. Shaaban, Mohammed G. Habsh, Rasha G. Mostafa, Shimaa K. Zewain

Menoufia Medical Journal

Objective The aim was to evaluate the relationships between serum adiponectin level and lumbar bone mineral density (BMD) in osteoporotic postmenopausal women with or without type 2 diabetes mellitus. Background Adiponectin is a novel adipocytokine that could influence bone metabolism. Patients and methods This case–control study was conducted on 55 postmenopausal women selected from diabetic endocrinology inpatient and outpatient clinics. Patients were divided into three groups: osteoporotic group (group A), which included 20 nondiabetic osteoporotic postmenopausal women; diabetic osteoporotic group (group B), which included 20 type 2 diabetic osteoporotic postmenopausal women; and control group (group C), which included 15 nonosteoporotic, …

Hemoglobina Glicosilada Un Factor Aliado En La Prevención De Infección Postquirúrgica Del Pie Diabético, Angela Marcela Villanueva Del Busto, Fiorella Rocío Arce-Huaroto

Revista de la Facultad de Medicina Humana

En este trabajo se ha realizado una búsqueda exhaustiva de estudios que evidencien el efecto de la Hemoglobina glicosilada (HbA1c) en el desarrollo de infección post quirúrgica en paciente con pie diabético. En nuestro país la prevalencia de pacientes con diabetes mellitus alcanza hasta un 8.4%, al respecto se sabe que una de las mayores complicaciones de esta enfermedad es el desarrollo de pie diabético y que consecuentemente a esta patología hasta un 20% de estos pacientes termina en una amputación, se sabe también que los pacientes con diabetes mellitus tienen un alto riesgo de complicaciones postoperatorias, incluyendo infecciones, curación …

Effect Of High Glucose On Ocular Surface Epithelial Cell Barrier And Tight Junction Proteins, Saleh M. Alfuraih, Ashley Barbarino, Christopher Ross, Kiumars Shamloo, Vishal Jhanji, Miao Zhang, Ajay Sharma

Pharmacy Faculty Articles and Research

PURPOSE. Patients with diabetes mellitus are reported to have ocular surface defects, impaired ocular surface barrier function, and a higher incidence of corneal and conjunctival infections. Tight junctions are critical for ocular surface barrier function. The present study was designed to investigate the effect of high glucose exposure on human corneal and conjunctival epithelial cell barrier function and tight junction proteins.

METHODS. Human corneal and conjunctival epithelial cells were exposed to 15 mM and 30 mM glucose for 24 and 72 hours. The barrier function was measured using transepithelial electrical resistance (TEER). The cell migration was quantified using scratch assay. …

Frequency Of Silent Carotid Artery Stenosis In Diabetics And Its Associated Factors: An Analysis In Tertiary Care Hospital, Faiza Sadaqat Ali, Nimrah Bader, Bader Faiyaz Zuberi, Sabiha Banu

Section of Diabetes, Endocrinology and Metabolism

Objective: To estimate frequency of silent carotid artery stenosis and its associated factors in diabetic patients attending a tertiary care hospital.
Methods: This cross-sectional study was conducted in tertiary care Civil Hospital, Karachi from March 2019 to September 2019,. A total of 166 patients with Diabetes Mellitus were included in this study. Brief history was taken for the duration of DM, treatment, and smoking habits. Carotid artery stenosis (CAS) wafrs measured by Doppler ultrasound of right and left common, internal, and external carotid arteries.
Results: Frequency of silent carotid artery stenosis (CAS) in diabetic patients was observed in 28.92% (48/166) …

Understanding Type 2 Diabetes Mellitus Among Haitian American Women: A Cultural Perspective, Balkys L. Bivins, Indra R Hershorin, Lonar M. Umadhay

Faculty Articles

The prevalence of type 2 diabetes mellitus (T2DM) is 19.7% in Haiti (DeGennaro et al., 2018). Haitian American women (HAW) experience difficulties with adherence to T2DM treatment and management (Bivins, 2016; Magny-Normilus et al., 2019; Vimalananda et al., 2011; Huffman et al., 2013); however, no previous study was found that focused exclusively on Haitian American women with T2DM. Van Manen's six research activities guided this phenomenological qualitative inquiry. Recruitment included 25 Haitian American women (N = 25) with T2DM from three South Florida counties. Data were collected using a vignette and audio-recorded semi-structured interviews with open-ended questions. Recordings were then …

Diabetes Mellitus, Cara Young

Nursing Student Class Projects (Formerly MSN)

There are two types of diabetes mellitus, Type 1 which involves a decrease in insulin production and Type 2 which is related to an impaired sensitivity to insulin due to peripheral insulin resistance (Chesworth, 2019). Type 1 diabetes is a dysfunction of the pancreas that an individual is usually born with and affects about 10 percent of the diabetic population. Type 2 diabetes is a product of obesity and age that affect the body’s sensitivity to insulin, not a problem with its production, and affects the remaining 90 percent of the diabetic population (Chesworth, 2019). The hyperglycemia that comes with …

The Benefits Of Intermittent Fasting On Patients With Diabetes Mellitus, Alissa Guinto

Physician Assistant Studies | Student Articles

Diabetes mellitus is the 7^th leading cause of death in the United States, comprising about 10% of the population. With intermittent fasting gaining popularity in the media as a method to lose weight and control chronic illness, patients with diabetes would likely turn to any of the fasting methods in order to better manage their disease. However, there is a paucity of information to support whether intermittent fasting is an effective method to control diabetes, in conjunction with lifestyle modifications and anti-diabetic pharmacotherapy. This review sought to identify clinically relevant human studies that provide evidence that intermittent fasting is …

Supporting Positive Lifestyle Changes Among Patients With Diabetes Mellitus Type 2, Alison Tynan

Nursing | Senior Theses

The following thesis is a compilation of literature reviewed to formulate background research for a pilot study. The literature reviewed pertains to the potential benefit of added case management for patients with diabetes mellitus type 2. A proposed pilot study, based off of this research, aims to identify topics, tools, facts, and changes that can be made to case management to improve not just the biological aspects, like HbA1c levels, but the mental and emotional as well to allow for whole person care.

The primary question being asked is “what types of support do people with diabetes mellitus type 2 …

Transitioning To Value-Based Diabetes Care: A Call For Action Derived From Primary Care Providers In South Florida, Francois Sainfort, Julie A. Jacko, Johannes Vieweg

HCA Healthcare Journal of Medicine

Background: In Florida, 2.4 million people have diabetes and 5.8 million are pre-diabetic. Not only has the prevalence of diabetes doubled over the past 20 years from 5.2 in 1992 to 11.2 in 2014, but the Centers for Disease Control and Prevention expects 1 out of every 3 adults will have diabetes by the year 2050. In addition, in every year since 1996, Florida well exceeds the national levels in terms of prevalence of diabetes, and the gap is getting wider. A study was conducted to gather information from key physician stakeholders as to how to address unmet needs of …

An Assessment Of Oral Health Discussion Between Primary Care Providers And Their Patients With Diabetes, Rocio Huizar

Dental Hygiene ETDs

Individuals diagnosed with diabetes mellitus, are not given information regarding the relationship between diabetes and oral health. The purpose of this study was to assess whether primary care providers discuss the association between oral health and diabetes mellitus to their patients with diabetes, if they refer to dental providers and where is oral health ranked in importance during a routine exam.

A secure electronic survey was sent to the Medical Director of the Department of Family and Community Medicine, requesting it be forwarded to providers in each primary care clinical facility. Survey was open for two weeks, ten surveys were …

Diabetes Mellitus And Necrotizing Fasciitis – A Deadly Combination; Case Report, Alexandra Toma, Laura Mazilu, Andra Iulia Suceveanu, Florentina Gherghiceanu, Camelia Sandu, Cristina Bica, Liliana Florina Andronache, Ioana Paunica, Lavinia Alexandra Moroianu

Journal of Mind and Medical Sciences

Necrotizing fasciitis is a rapidly destructive affliction of soft tissues, with a mortality rate that may reach 73% of the cases. It is characterized by a progressive inflammation and extended necrosis of the subcutaneous tissue and the fascia. Necrotizing fasciitis was first described in 1848, and later in 1920 Meleney identified 20 patients in China in which the infection was presumably triggered by hemolytic streptococcus, linking pathological bacteria to the condition. In 1952, Wilson coined the term necrotizing fasciitis although without successfully identifying the specific pathological bacteria involved. In most cases, both risk and aggravating factors are present, the main …

Effects Of Prolactin On Ventricular Myocyte Shortening And Calcium Transport In The Streptozotocin-Induced Diabetic Rat, Frank C. Howarth, Gunnar Norstedt, Oleksiy I. Boldyriev, Muhammad A. Qureshi, Ozaz Mohamed, Khatija Parekh, Balaji Venkataraman, Sandeep Subramanya, Anatoliy Shmygol, Lina T. Al Kury

All Works

© 2020 Cardiology; Cell biology; Endocrinology; Molecular Biology; Pathophysiology; Pharmacology; Physiology; prolactin; Diabetes mellitus; heart; Ventricular myocytes; Contraction; Calcium

Juvenile Diabetes Mellitus With Exocrine Pancreatic Insufficiency In A Thai Bangkaew Dog: A Case Report, Jeerawat Soonthornsit, Weerachai Anpranit

The Thai Journal of Veterinary Medicine

An 8-month-old intact male Thai Bangkaew bred dog presented with polyuria, polydipsia, polyphagia, exercise intolerance and weight loss over 2 weeks. The serum biochemistry profiles revealed hyperglycemia, glycosuria and high serum fructosamine concentrations indicating the development of diabetes mellitus. The dog had a good response to a half-dose of intermediate-insulin injection twice daily monitored by the improvement of clinical signs and serum fructosamine. This was supposed to be due to the partial destruction of islets of Langerhans. Two months later, voluminous diarrhea with greasy stools, dry coat hair and generalized alopecia were observed. However, the clinical signs of diabetes mellitus, …

Relationship Between Oral Health And Clinical Osteoporosis Among Hospitalized Patients With And Without Diabetes, Kenneth Izoura, Gayle Allenback, Amber Champion, Civon Gewelber, Michael Neubauer

School of Medicine Faculty Publications

Objective: Diabetes mellitus (DM) is associated with poor oral health and osteoporosis (OP). The aim of this study was to assess the relationship between OP, periodontal disease (PD), and other dental and health outcomes in a cohort of hospitalized patients with and without DM. Method: Using a cross-sectional study design, we enrolled consecutive hospitalized patients. We administered a questionnaire to gather demographic information, oral health history, smoking history, and history of OP. We inspected their dentition and reviewed their charts. Data were analyzed using t-tests, chi-square tests, and logistic regression models. Result: Out of 301 patients enrolled, 275 had PD, …

Diabetic Cardiomyopathy: Understanding The Independent Relationship Between Diabetes And Heart Failure, W. Tyler Crawley, Rage Geringer Md, Jason Snarr Do, Elizabeth Hicks Md, Oliwier Dziadkowiec

Internal Medicine

No abstract provided.

La Carga Global De La Diabetes: Prevalencia, Prevención Y Recomendaciones, Miguel Pérez, Jenette Smith

Revista de la Facultad de Medicina Humana

La carga mundial de diabetes, una de las principales causas de muerte, morbilidad y gastos en atención médica, ahora representa una de las mayores amenazas para la salud y el desarrollo mundiales. Los principales determinantes biológicos y de comportamiento de la diabetes son las dietas de azúcares y grasas procesadas, los bajos niveles de actividad física, el sobrepeso y la obesidad (Birn, Pillay, y Holtz, 2017). Como una de las cuatro principales enfermedades no transmisibles (ENT), Diabetes Mellitus (DM) ha atraído una gran atención por parte de las autoridades sanitarias mundiales. De hecho, la Organización Mundial de la Salud ha …

Diabetes And Depression: Relation To Glycemic Control, Hala Ahmadieh

BAU Journal - Health and Wellbeing

Diabetes mellitus is a worldwide highly prevalent chronic metabolic disorder, characterized by hyperglycemia, and is associated with significant complications, including the microvascular complications such as neuropathy, retinopathy and nephropathy and the macrovascular complications such as cardiovascular, cerebrovascular disease and peripheral vascular disease, thus leading to significant morbidity and mortality. Patients with diabetes were found to be 1.4-3 times more likely to suffer from comorbid depression when compared to non-diabetics, and depression in diabetes is usually persistent and/or recurrent. Depression was found to be increased among patients with type I and type II diabetes mellitus, which have higher glycosylated hemoglobin. Association …

Mapping Of Diabetes Susceptibility Loci In A Domestic Cat Breed With An Unusually High Incidence Of Diabetes Mellitus, Lois Balmer, Caroline Ann O’Leary, Marilyn Menotti-Raymond, Victor David, Stephen O’Brien, Belinda Penglis, Sher Hendrickson, Mia Reeves-Johnson, Susan Gottlieb, Linda Fleeman, Dianne Vankan, Jacquie Rand, Grant Morahan

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Genetic variants that are associated with susceptibility to type 2 diabetes (T2D) are important for identification of individuals at risk and can provide insights into the molecular basis of disease. Analysis of T2D in domestic animals provides both the opportunity to improve veterinary management and breeding programs as well as to identify novel T2D risk genes. Australian-bred Burmese (ABB) cats have a 4-fold increased incidence of type 2 diabetes (T2D) compared to Burmese cats bred in the United States. This is likely attributable to a genetic founder effect. We investigated this …

Systematic Review Of Loss-Frame Messaging And Change In Health Behavior, Eddie Jean Simmons

Walden Dissertations and Doctoral Studies

Recent analysis estimates Type II diabetes affects 23.4 million people in the US. Approximately 30% of these patients are not in optimal control of their diabetes, raising risks for blindness, amputation, and cardiac disease. A gap in diabetes education practice is that traditional positive-framed messaging has not persuaded many patients to modify their self-management behaviors. There is a need for alternative ways to communicate the risks of not managing the disease to patients who may have different health beliefs. The purpose of this systematic review was to examine the best available evidence regarding the efficacy of loss-frame messaging when used …

Validity And Reliability Of The Turkish Version Of The Michigan Neuropathy Screeninginstrument, Duygu Aktar Reyhani̇oğlu, Süleyman Cem Adiyaman, Murat Bektaş, Onur Bulut, Başak Özgen Saydam, Firat Bayraktar, Bi̇lge Kara

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to demonstrate the validity and reliability of the Turkish version of the Michigan Neuropathy Screening Instrument (MNSI-TR). Materials and methods: The study included 127 patients aged 45-76 years who were previously diagnosed with type 1 or 2 diabetes. Stability of the instrument was assessed by intraclass correlation coefficient. Reliability of the MNSI-TR was assessed using the Kuder- Richardson formula 20 test, item-total correlations, and floor/ceiling effect. Validity was evaluated with receiver operating characteristic curve analysis. A logistic regression model was used to determine to what degree the MNSI-TR explain nerve conduction study (NCS) …

Improving Assessment, Documentation, And Ordering Of Diabetic Retinopathy Screenings In A Primary Care Clinic, Lauren N. Motto

DNP Projects

Abstract

BACKGROUND: Diabetes mellitus (DM) is the leading cause of new blindness in American adults. As the number of people with type 2 diabetes continues to increase, the total number of people affected by diabetic retinopathy (DR) will continue to rise. Improved access to screening for DR, followed by treatment, if necessary, can reduce the progression to vision loss. Despite national recommendations, less than half of Americans with DM complete annual diabetic retinopathy screenings (DRS).

PURPOSE: The purpose of this project was to improve assessment, education, documentation, and ordering of DRS for patients with a diagnosis of type 1 and/or …