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Articles 1 - 6 of 6
Full-Text Articles in Medicine and Health Sciences
Review Of The Cardiovascular Toxicity Of Amitriptyline Treatment For Canine Neuropathic Pain, Saikaew Sutayatram, Kumpanart Soontornvipart, Piyasiri Glangosol
Review Of The Cardiovascular Toxicity Of Amitriptyline Treatment For Canine Neuropathic Pain, Saikaew Sutayatram, Kumpanart Soontornvipart, Piyasiri Glangosol
The Thai Journal of Veterinary Medicine
Nowadays, the lifespan of pets has been increased by improvements in veterinary practice but age-related disorders are also increasing. Several nervous system attenuations are well-known to be the result of aging and/or pathological lesions. In many cases, neuropathic pain (NP) can develop and cause a significant impact on the clinical outcome and quality of life. With the difficulty in identification of the specific cause of NP, most NP management is planned according to clinical manifestations and recommended trial therapy. The drug of choice for trial therapy seems to be amitriptyline, a tricyclic antidepressant with multiple effects on neurotransmitter receptors and …
Immunohistochemical Staining Of Peroxisome Proliferatoractivated Receptor Alpha And Gamma In Normal, Benign, And Malignant Canine Mammary Tissues, Wuthichai Klomkleaw, Promporn Raksaseri
Immunohistochemical Staining Of Peroxisome Proliferatoractivated Receptor Alpha And Gamma In Normal, Benign, And Malignant Canine Mammary Tissues, Wuthichai Klomkleaw, Promporn Raksaseri
The Thai Journal of Veterinary Medicine
The peroxisome proliferator-activated receptors (PPARs) belong to nuclear receptor superfamily acting as transcription factors related to lipid and glucose metabolism. There are 3 subtypes including PPARα, PPAR, and PPAR. PPARα and PPAR activations can inhibit tumor cell proliferation and differentiation in many cell types. However, the expressions of these receptors in canine mammary tissue are still unknown. This study was performed to investigate the expressions of PPARα and PPAR in normal, benign, and malignant canine mammary tissues. Twenty four bitches at the age of 5-15 years old, which undergone unilateral mastectomy, were used in the study. Mammary tissues were sectioned …
Detection Of Transforming Growth Factor Beta 1 In Normal Dogs And Dogs With Degenerative Mitral Valve Disease, Wiyada Winyuchonharoen, Somporn Techangamsuwan, Sirilak Disatian Surachetpong
Detection Of Transforming Growth Factor Beta 1 In Normal Dogs And Dogs With Degenerative Mitral Valve Disease, Wiyada Winyuchonharoen, Somporn Techangamsuwan, Sirilak Disatian Surachetpong
The Thai Journal of Veterinary Medicine
Degenerative mitral valve disease (DMVD) is a common finding of acquired heart diseases in small and medium-sized adult dogs. Transforming growth factor beta 1 (TGF-β1) was found to increase in valves of DMVD dogs. However, plasma TGF-β1 concentrations in dogs with DMVD have not been evaluated before. The objective of the present study was to compare the plasma concentration of TGF-β1 between normal dogs and dogs with DMVD by using an ELISA technique. This measurement might help to distinguish dogs with DMVD from healthy dogs. The Mann-Whitney U test was used to compare plasma TGF-β1 concentrations between the two groups. …
Prevalence Of Bacteremia In Dogs Admitted To An Intensive Care Unit With Intravenous Catheterization, Pattrarat Chanchaithong, Sukullaya Ritthikulprasert
Prevalence Of Bacteremia In Dogs Admitted To An Intensive Care Unit With Intravenous Catheterization, Pattrarat Chanchaithong, Sukullaya Ritthikulprasert
The Thai Journal of Veterinary Medicine
Bacteremia is a common complication in hospitalized patients, and intravenous catheterization is a routine intervention in dogs in intensive care units (ICU). This study aimed to investigate bacteria associated with bacteremia in an ICU of a veterinary teaching hospital during 2013-2014. Fifty dogs admitted to the ICU were included in this study. Twenty-four dogs (48.00%) presented bacteremia by blood culture. Bacterial species were identified, including Klebsiella pneumoniae (8/24), Pseudomonas aeruginosa (7/24), Staphylococcus pseudintermedius (3/24), Escherichia coli (2/24), Bacillus sp. (1/24), Acinetobacter sp. (2/24) and Burkholderia cepacia (1/24). Only five dogs had positive catheter colonization by identical bacterial species with those …
An Aged Canid With Behavioral Deficits Exhibits Blood And Cerebrospinal Fluid Amyloid Beta Oligomers, Clare Rusbridge, Francisco J. Salguero, Monique Antoinette David, Kiterie M. E. Faller, Jose T. Bras, Rita J. Guerreiro, Angela C. Richard-Londt, Duncan Grainger, Elizabeth Head, Sebastian G. P. Brandner, Brian Summers, John Hardy, Mourad Tayebi
An Aged Canid With Behavioral Deficits Exhibits Blood And Cerebrospinal Fluid Amyloid Beta Oligomers, Clare Rusbridge, Francisco J. Salguero, Monique Antoinette David, Kiterie M. E. Faller, Jose T. Bras, Rita J. Guerreiro, Angela C. Richard-Londt, Duncan Grainger, Elizabeth Head, Sebastian G. P. Brandner, Brian Summers, John Hardy, Mourad Tayebi
Pharmacology and Nutritional Sciences Faculty Publications
Many of the molecular and pathological features associated with human Alzheimer disease (AD) are mirrored in the naturally occurring age-associated neuropathology in the canine species. In aged dogs with declining learned behavior and memory the severity of cognitive dysfunction parallels the progressive build up and location of Aβ in the brain. The main aim of this work was to study the biological behavior of soluble oligomers isolated from an aged dog with cognitive dysfunction through investigating their interaction with a human cell line and synthetic Aβ peptides. We report that soluble oligomers were specifically detected in the dog's blood and …
Complications Of Ultrasound-Guided Cystocentesis In Companion Animals: 21 Cases (2005-2016), Sabrina Manfredi, Cibele Carvalho, Paolo Fonti, Giacomo Gnudi, Francesca Miduri, Martina Fabbi, Eleonora Daga, Manuela Ravera, Simona Morabito, Edoardo Auriemma, Ilaria Parroccini, Mattia Bonazzi, Antonella Volta
Complications Of Ultrasound-Guided Cystocentesis In Companion Animals: 21 Cases (2005-2016), Sabrina Manfredi, Cibele Carvalho, Paolo Fonti, Giacomo Gnudi, Francesca Miduri, Martina Fabbi, Eleonora Daga, Manuela Ravera, Simona Morabito, Edoardo Auriemma, Ilaria Parroccini, Mattia Bonazzi, Antonella Volta
Turkish Journal of Veterinary & Animal Sciences
Complications of cystocentesis in dogs and cats are seldom reported. The aim of this study was to describe clinical and ultrasonographic features of complications after diagnostic cystocentesis. Medical records of animals that underwent ultrasound-guided diagnostic cystocentesis (UGDC) were retrospectively reviewed to describe adverse events. The inclusion criteria were: ultrasound report describing the complication, signalment, clinical history, urine culture, and surgical exploration or necroscopic findings if present. Images of ultrasonographic examination were reviewed. Complications were classified as minor and major. Minor complications were defined as self-limited events; major complications were those that led to prolonged hospitalization and required intensive therapy or …