Medicine and Health Sciences Commons^™

Educating Anesthesia Providers On The Physiological Effects And Anesthesia Implications Of Cannabis, Carmel Loud

Doctor of Nursing Practice Projects

In the U.S., currently 37 states have legalized cannabis for medicinal use prescribed by qualified medical professionals (National Conference of State Legislatures [NCSL], 2022). In 2012, the legalization of recreational cannabis began; as of 2022, 19 states have legalized the recreational use of marijuana (NCSL, 2022). This project aimed to optimize care for patients using cannabis by increasing anesthesia provider knowledge about cannabis. The project's aim was accomplished through a thorough review of the current medical literature and implementation of education to anesthesia providers about the physiological effects and anesthesia implications of cannabis. Thirteen CRNAs took a pre- and post-quiz …

Sex Differences In The Effects Of Cortisol On Muscle Characteristics: A Meta-Analysis, Natalie Bitetti

CMC Senior Theses

Background: Cortisol plays a central role in both muscle breakdown and growth. These effects are highly dependent on dose and interactions with other hormones. It is known that men and women show considerable differences in their muscle structure and physiology, which are largely driven by hormonal differences. Cortisol release patterns may also vary between the sexes, with current research showing considerable disagreement. The interplay between cortisol and muscle, two highly variable and sexually dimorphic factors, may prove to have different effects in males versus females.

Objective: This meta-analysis integrates existing research on sex differences in cortisol-muscle physiology with existing research …

Impacts Of Environmental Stressors On Native South Dakota Amphibian Physiology And Survival, Danielle Jean Galvin

Dissertations and Theses

Amphibian populations around the world are declining, with some of the most likely drivers behind these declines including emerging infectious diseases and environmental contaminants. To address major gaps in the current literature, I sought to evaluate the effect of two major environmental stressors on various aspects of amphibian physiology: emerging infectious diseases and environmental contaminants. Emerging infectious diseases of amphibians include fungal, viral, and parasitic pathogens which have expanded in host range, either geographically or in competent host species. Environmental contaminants include chemicals which may be naturally occurring in the environment, or which may be introduced to the environment, often …

Identification And Assessment Of Fixed Versus Growth Mindsets In Human And Anatomy Physiology Undergraduate Students, Jayanti Shukla

Honors Theses

Fixed mindsets and growth mindsets are present in individual’s attitudes, affecting their motivations to complete responsibilities or overcome challenges. In this study, we aim to identify and assess the mindsets of undergraduate students partaking in the Human Anatomy and Physiology (HAP) undergraduate course at the University of Mississippi, the gateway course being well-known for its difficulty and being described as “daunting” to many allied-health majors. By utilizing Carol Dweck’s growth mindset model, we are interested in determining whether students possess a “fixed” mindset versus a “growth” mindset, in conjunction to assessing their classroom performance correlating with that demonstrated mindset. An …

Eco-Interoception: What Plants, Fungi And Protista Have Taught My Body, Sara Riley Dotterer

Art Theses and Dissertations

To me, ecology is the relational, full-body awareness that I am made up of and deeply connected to everything around me; and for better or worse, this is reciprocal. I form ecotones, an ecological transitional zone between two ecosystems, with the world around me. I use this ecotonal lens to blur binaries and dissolve boundaries between me and the world “outside my body.” During my Masters of Fine Arts at Southern Methodist University, I have continuously explored and represented the lives of various more-than-human species outside of my body, including plants, fungi and protista through an ecotonal lens. Although these …

Oxygen Consumption In Highly Skilled Baseball Pitchers, Jesse Clingman

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to describe the physiological demands of highly skilled baseball pitchers during pitching, along with pitch metrics. Three junior college and three professional (n = 6) baseball pitchers participated in this study. Participants completed a graded exercise test (GXT) to volitional exhaustion to determine maximal oxygen consumption (VO2 max) and estimated body fat percentage, height, and body mass were measured on day one of testing. Next, participants faced live batters on a baseball field while wearing a portable metabolic analyzer (Cosmed K5) to measure respiratory gases including oxygen consumption (VO2) and carbon dioxide produced (VCO2) …

Impacts Of Dietary Restriction On A Drosophila Model Of Werner Syndrome, Eileen Sember

College of Arts & Sciences Senior Honors Theses

Werner syndrome (WS) is an autosomal recessive disorder that results in premature aging and occurs in 1 in 1,000,0000 to 1 in 10,000,000 people. In humans, WS is the result of mutations that render the WRN gene, that contains a helicase and an exonuclease domain, non-functional. Currently, there is no cure for WS in humans, making dietary and lifestyle interventions attractive for increasing the quality and longevity of lives. Diet restriction (DR) has been shown to extend the lifespan of several model organisms, including Drosophila melanogaster, making it a strong candidate for WS treatment. In this thesis, mutant flies …

The Effect Of Golf Bag Load Carriage On Lower Body Force Expenditure, Ryan Collins-Smith

Honors College Theses

Golf is one of the fastest growing sports worldwide and as one of the most difficult sports to excel at, every area of improvement is important. Load carriage, lower body force production, and perceived exertion are keys to improving. The purpose of this project was to investigate the influence of a variety of golf bag load carriage styles on vertical jump performance and perceived exertion. The different modes of golf bag load carriage were no golf bag (1), single-strap golf bag (2), double-strap golf bag above sacrum height (3), double-strap golf bag below sacrum height (4), and push cart for …

Chronic Circadian Disruption Increases Risk For Cardiovascular Disease, Jazmine I Benjamin

All ETDs from UAB

Circadian disruption is a disturbance in biological timing which can occur within or between different organizational levels, ranging from molecular rhythms within specific cells to misalignment of behavioral and environmental cycles. Previous work has shown that changing the timing of food availability is sufficient to lower blood pressure and improve insulin sensitivity in prediabetic males, demonstrating the importance of timing of food intake for cardiovascular health. Findings from our group demonstrated that less than one week of mistimed feeding is sufficient to invert diurnal blood pressure rhythms, although kidney excretory rhythms and kidney function remained aligned with the light-dark cycle. …

An Examination Of Kinanthropometric And Physical Injury Risk Factors In Elite Australian Football, Callum J. Mccaskie

Theses: Doctorates and Masters

Kinanthropometric assessment is an integral part of understanding an athlete’s physical profile and readiness for competition. This typically includes a variety of different assessments which serve to quantify body shape, proportion, and composition in a bid to understand human physiology. Common assessments include stature, body mass, limb ratios, body circumferences, body mass index, skinfold testing, body composition testing, and musculoskeletal morphological evaluations. Specifically, kinanthropometric evaluations have involved the characterisation of athletes according to sport, sex, competition level and playing position. While this has provided researchers and practitioners with greater insight into athletic phenotypes, more purposeful kinanthropometric assessments which focus on …

Assessment Of Motivation In Human Anatomy And Physiology Students, Mary Whitehead

Honors Theses

Motivation is the key to success in difficult science courses such as Human Anatomy and Physiology. Students may possess intrinsic motivation, or motivation for enjoyment, extrinsic motivation, or motivation for a reward, or amotivation, a lack of motivation at all. The goal of this experiment was to identify better ways of helping students succeed in Human Anatomy and Physiology (HAP) at the University of Mississippi, determine when motivational efforts seem to decrease during the semester, and identify how to better develop intrinsic motivation in students. There was a significant relationship between many of the student’s survey responses to their exam …

Assessment Of Spatial Skills In Human Anatomy And Physiology Students, Abigail Carroll

Honors Theses

Visual spatial skills are an individual’s ability to mentally and manipulate the shapes, forms and positions of objects. Spatial skills are necessary for adequate learning in many settings. Few studies have assessed spatial skills compared to success in Anatomy and Physiology in undergraduate students. Most students in this course are on a health profession track. Due to the increasing health care demands and need for competent health care professionals, this study assesses the innate spatial skill ability in students and acquired additional learned spatial skills. This study tests 17 students with the paper-folding test, blank page test, and two surveys …

Ulcerative Colitis, Randy Kinietz

Nursing Student Class Projects (Formerly MSN)

This poster briefly covers the most important concepts of ulcerative colitis (UC). UC is a complex disease process and the exact etiology is not yet known. Many researchers are currently looking to find the cause of the disease and treatment options that can target the exact pathophysiological process. Nurses are instrumental in the care of UC, especially in an outpatient setting. Education on medications and proper follow-up appointments are the key to maintaining remission, reducing flare-ups, and cancer screening. Although UC is a complex disease, a multidisciplinary approach will reduce complications and prolong remission.

Physiological Stability During Oral Feeding In Preterm Infants: Associations With Feeding Behaviors And Cues, Cindy M. Lund

Graduate Research Theses & Dissertations

The purpose of this study was to examine the relationship between measures of physiological stability/instability during feeding. An additional aim was to determine if behaviors associated with physiological stability were also perceived as readiness or stress cues. Participants included 5 preterm infants (<37 weeks gestation) with no craniofacial anomalies. Infants were videotaped when they were taking at least 90% of prescribed volume. This study analyzed the common behaviors seen in preterm infants during bottle feeding to determine if there were associations with measures of physiological stability. Behaviors were also analyzed to determine which were perceived as indicating stress or readiness to feed by novice observers. Coding was conducted offline using Noldus Observer software.

Results revealed a statistically significant relationship between behaviors classified as stress cues and HR instability. There was not a significant association between stress cues and RR or SPO2. Binomial testing identified specific preterm infant feeding behaviors that were more often classified as stress cues, with significance noted in audible swallow and vocalization. Several of the specific preterm …

Impact Of 17-Beta Estradiol And Moderate-Intensity Exercise On Mesenteric Arterial Function Of Uc Davis Type-2 Diabetes Mellitus Rats, Md Rahatullah Razan

University of the Pacific Theses and Dissertations

The studies in this dissertation were designed to investigate the impacts of estrogen (17-β estradiol/E2) and moderate-intensity exercise (MIE) on the mesenteric arterial (MA) function of the University of California Davis type-2 diabetes mellitus (UCD-T2DM) Rat model. Our recent report suggests that diabetes impairs MA vasorelaxation in both sexes of the UCD-T2DM model. Particularly, we reported that MA from prediabetic male rats showed a greater impairment compared to that in prediabetic females. However, when females become diabetic, they exhibit a greater vascular dysfunction than males. Therefore, the aim of the first study was to investigate whether female sex hormone, specifically …

The Role Of Psychological Distress In Maintaining Exercise After Cancer Diagnosis, Patrick Tertulien

Walden Dissertations and Doctoral Studies

AbstractCancer affects the lives of thousands of people every day and is a leading cause of death. Exercise has been shown to yield mental and physical benefits for patients and survivors, but the experiences of cancer patients who face a multiplicity of psychological stressors have not been clearly described. The purpose of this qualitative study was to understand the psychological factors that are associated with continuing to exercise after cancer diagnosis, during and/or following their treatment. The focus was on how cancer survivors maintained a regular routine of exercise while experiencing psychological distress associated with cancer diagnosis, treatment, and concerns …

Viability Of Physiologically Timed Relaxation Interventions In Children With Asd, Nicholas Mendez

CMC Senior Theses

Autism Spectrum Disorder (ASD) is an increasingly common developmental disorder that changes how people experience the world and affects individuals’ social interactions and often leads to many adverse behaviors. Current literature dictates that a primary contributor to these adverse behaviors is that those with ASD have difficulty determining their own emotional states and determining the physiological signals that their body sends them. A study by Dr. Sarabadani et al. determined that it was possible to monitor the physiology of an individual with ASD and correlate certain signals to emotions, such as stress. These findings indicate the feasibility of establishing a …

Plasma Resuscitation Attenuates Intestinal Barrier Disturbance Following Hemorrhagic Shock., Jessica E. Schucht

Electronic Theses and Dissertations

Background: Intestinal ischemia-reperfusion injury (IIRI) following resuscitated hemorrhagic shock (HS/RES) leads to endothelial damage, microcirculatory dysfunction and intestinal barrier breakdown, increasing intestinal permeability. This pathologic process contributes pathophysiology of multiple organ dysfunction syndrome (MODS) in some trauma patients. Although vascular smooth muscle machinery remains intact, microvascular vasoconstriction occurs secondary to endothelial cell damage, resulting in further ischemia and organ injury. Used separately, resuscitation with Fresh Frozen Plasma (FFP) or Direct Peritoneal Resuscitation (DPR) improves the intestinal microcirculation and alleviates organ injury. Further examination of these effects individually or combined could aid in the resuscitation of hemorrhagic shock. Methods: Sprague Dawley …

Analyzing Leadership Opportunities Through Participant Perspective, Cathryn Yaggie Heinen

Theses/Capstones/Creative Projects

The Anatomy Academic Assistant (AAA) practicum is a peer-mentoring program that helps participants further develop leadership skills. The goal of this research was to analyze leadership qualities through participant perspective and analyze the effectiveness of the AAA practicum in enhancing these leadership qualities. A 25-question survey, measuring participant perspective, was designed to include both rating-scale questions and free response questions. Rating-scale questions used a Likert scale with a corresponding assigned value. Free response questions also provided qualitative data that was grouped into overarching themes in a generated word cloud. The assigned value averages showed that participants largely agreed with the …

Vocal Health Of Choral Singers From Kenya And The United States: Dysphonia And Vocal Fatigue In Relation To Musical Genres, Morgan Jolley Burburan

USF Tampa Graduate Theses and Dissertations

The purpose of this mixed-methods study was to investigate the vocal health of choral singers from Kenya and the United States and to determine whether genre (classical choral, traditional Kenya, and Contemporary Commercial Music [CCM]) had any impact on healthy vocal production, particularly as it related to vocal fatigue. Participants were adult singers (N = 94) in two semi-professional choirs, the Nairobi Chamber Chorus (NCC) from Kenya (n = 25) and the Festival Singers of Florida (FSOF) from the United States (n = 69). Singers’ perceived overall vocal health was measured using multiparametric clinical self-reporting instruments and acoustical assessment. Singers’ …

An Interpretive Phenomenological Study Of Adult Students’ Subjective Theories Of Critical Thinking In Anatomy And Physiology, Elizabeth Anne Dubofsky-Porter

Walden Dissertations and Doctoral Studies

Critical thinking is a vital skill for the success of recent graduates, both to increase academic success and improve employability after graduation, especially in health science fields. However, many adult students fail to engage in critical thinking, especially in core courses such as anatomy and physiology (A&P). The purpose of this interpretive phenomenological qualitative study was to better understand adult students’ subjective theories regarding critical thinking and how adult students perceive the use of and any barriers or challenges to critical thinking in A&P while enrolled at Technical University. The theoretical framework that grounded this study was the Paul-Elder theory …

Insurance Status And Obesity As Predictors Of Cost In Trauma Care, Emily Homer

University of the Pacific Theses and Dissertations

Insurance is a vital factor in the billed cost to the patient, but to what degree does insurance explain the amount a patient is left to pay? Also, does obesity further influence patient’s billed cost? This thesis assesses the type of thoracic trauma patient, insurance status, and their billed cost. Database variables were analyzed in IBM SPSS 25. Table 1 characteristics were evaluated based on demographics and systematic hospital factors. Linear regressions used Private0_Government1 and BMI Obese n_y_ as independent variables while Total Patient Cost was the dependent variable. Private0_Government1 insurance explained .03% of Total Patient Charges. Private0_Government1 and BMI …

Influence Of Heating And Biological Sex On Vascular Dysfunction Associated With Long-Duration Sitting And Standing, Aaron Richard Caldwell

Graduate Theses and Dissertations

Purpose: The purpose of these studies was to determine if arterial angulations (through sitting or standing), shear stress (through local heating), or a combination of these factors affected vascular function. Moreover, this studied estimated the magnitude of the effect that biological sex has on these vascular responses. Methods: Twenty-six healthy, young (18-40 years old) males (n=13) and females (n=13) completed two experimental trials (2-h sitting and 2-h standing). In a randomized fashion, one leg was passively heated in order to increase shear rate. Following a 48-h washout, participants returned to the laboratory to complete the other trial. Flow-mediated dilation (FMD) …

Integration Of Cone Photoreceptor Signals In Macaque Lgn Neurons, Paul B. Brown

All ETDs from UAB

Despite advances in the understanding of the primate visual system, much is yet to be learned about the way light signals sum to create our perception of the world. This is especially true at the simplest level of visual processing—the summation of two individual cone photoreceptor signals. How such signals combine to create visual perception has not been assessed in vivo. We used an adaptive optics scanning laser ophthalmoscope (AOSLO) to deliver binarized noise movies to identified groups of cones within the receptive fields of neurons in the macaque lateral geniculate nucleus (LGN). Recordings of neural action potentials within the …

The Manifestations Of Fatigue In Amateur Boxing Performance, Emily C. Dunn

Theses: Doctorates and Masters

A subjective method of judgment, the “Ten Point Must-System” (TPMS), was introduced into amateur boxing in 2013. To be successful, boxers must deliver forceful punches and exert dominance over an opponent. There has been limited research examining the strategies used by boxers to win fights under the TPMS and whether these strategies induce fatigue that is sufficient to significantly affect punch force. The overall objective of the five studies contained in this thesis was to describe, in relation to fatigue, the performance characteristics of male amateur boxers under the TPMS, and improve our understanding of the physical characteristics associated with …

Improving Techniques To Study Equine Cervical Mucociliary Clearance, Melissa A. Hawkes

Electronic Theses and Dissertations

Bacterial uterine infections inflict major losses on the equine breeding industry. These infections usually arise from bacteria introduced at breeding. Micro-currents propelled by ciliated cells between the folds of the uterus and cervix have been proposed as a means by which contaminants are expelled. Previous data have shown possible ciliary micro-currents propelling carbon particles, occasionally rotating, through cervical folds. However, adherence to the epithelium may have interfered with movement of carbon in these studies. Therefore, we tested potentially non-adherent substances to reveal ciliary micro-currents on the equine cervix under high magnification video-endoscopy. We hypothesized that polyethylene green microspheres 1 - …

Allergen Specific Immunotherapy And The Effect On Allergy Induced Asthma, Cord Tanner Landrum

Physician Assistant Scholarly Project Papers

Allergies are a major public health problem affecting over 300 million people worldwide (Asamoah et. al). An allergic response can occur when a harmless substance, such as tree pollen, is inhaled into the body and mistakenly identified as a harmful substance. Antibodies then bind to the allergen causing a release of chemicals that leads to symptoms such as nasal congestion, runny nose, itchy eyes or skin reactions. For some people, this reaction can also affect the lungs and airways leading to asthma symptoms.

This review analyzes articles from PubMed, Cochran, Clinical Key and references found from UpToDate articles to assess …

Improved Physiology And Psychosocial Well-Being For Children With Physical Disabilities Through Virtual Reality Immersion, Bethany D. Fralish

Honors Undergraduate Theses

The purpose of this case study was to examine the physiological and psychosocial effects of an immersive virtual reality (VR) system in a female, young adult with right side paralysis following a left hemisphere brain bleed in order to determine the usefulness of immersive VR for children with physical disabilities, in particular, cerebral palsy (CP). The current study consisted of six sessions over a span of three weeks, with each session lasting approximately 45 minutes. Physiological factors (upper body mobility, heart rate variability) were assessed via a hand use questionnaire and a heart rate monitor, while psychosocial factors (e.g. positive …

Gait Changes During Exhaustive Running, Nathaniel I. Smith

Masters Theses

Runners adopt altered gait patterns as they fatigue which may increase energy expenditure and susceptibility to certain overuse injuries. Previous investigations have described changes in muscle performance and kinematic gait variables resulting from running fatigue. The purpose of this investigation was to characterize changes in joint moment patterns that develop as runners fatigue in order to better understand the kinetic bases for kinematic fatigue effects. It was hypothesized that when fatigued, runners would demonstrate increases in stance time, peak stance phase knee flexion angle, peak knee extension moment, peak swing phase hip flexion moment, and hip extension and plantarflexion angular …

The Effects Of The Menstrual Cycle On Agility, Kheniser G. Karim

ETD Archive

It has long been speculated that the menstrual cycle affects athletic performance. Whether athletic performance is impacted by menstrual cycle phase is dependent upon an array of factors: the type of activity (i.e., aerobic or anaerobic); oral contraceptive (OC) use; and, possibly, if mental processing is required during the execution of the task. Prior research has indicated that alterations in estradiol (E2) affects cognitive performance. However, there is a paucity of information about whether E2 modulates the speed of cognitive processing in a sports setting, which may cause alterations in sport performance throughout the menstrual cycle. Additionally, variations in E2 …