Medicine and Health Sciences Commons^™

Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

Use your break to expand your knowledge by checking out the many Grand Rounds posted in the Jefferson Digital Commons. Topics range from nasal reconstruction to sexuality and aging. With hours of Grand Rounds to experience (see some samples below), your holiday will transform from boredom to excitement! Happy holidays from the Jefferson Digital Commons!

A Word From The Writing Center (November 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Stylish academic writing
• The Write Stuff

Successes And Limitations Of Hepatitis C Screening In The Inpatient Setting: Initial Impact Of Pa Act Of 87 (Apha Roundtable Discussion), Madalene Zale, Mph Candidate, Ashley Park, Mph, Francis Nelson, Ms, Priya Mammen, Md, Mph

College of Population Health Lectures, Presentations, Workshops

The Problem:

• Estimated 3.2 million in US with chronic HCV; Baby Boomers 5 times more likely to be infected compared to other cohorts
• Complex nature of HCV requires confirmation of HCV Ab screens to determine management and treatment needs.

Round table held at 2017 Annual APHA meeting in Atlanta, Georgia

Delaware Health Sciences Alliance Global Health Symposium: Refugee And Immigrant Access To Care Locally And Globally

Global Health Events

Welcome to the 6th annual Global Health Symposium! As always, we are pleased to highlight the latest in our growing Global Health interests across the DHSA. The Delaware Health Sciences Alliance is a partnership of:

• Christiana Care Health System
• Jefferson Philadelphia University & Thomas Jefferson University
• Nemours / Alfred I. duPont Institute for Children
• University of Delaware

A Word From The Writing Center (October 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Selecting a target journal using journalguide.com
• Teaching and Communication Skills workshops

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 66, Issue 2, Fall 2017

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• Introducing the New Jefferson: One Name. Two Legacies. Infinite Possibilities
• The PhiladelphiaU Story: A History of Change and Innovation
• Two Alumnae, One Vision: A New Home Base for All Graduates
• Second Opinions for Docs, Second Chances for Patients: The Jefferson Angioplasty Center Helps Cardiac Patients Avoid Open Heart Surgery
• Dean's Column
• Findings: Molecule May Help Maintain Brain's Synaptic Balance
• The Families We Choose: A Message from Elizabeth Dale
• On Campus
• Basil Harris, MD '02: Merging Medicine, Engineering, and Design to Revolutionize Digital Healthcare
• Big Things, Small Beginnings: Jefferson Surgeons Are Exploring New Therapies That May Make Standard …

A Word From The Writing Center (September 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing Tip: Sentences that start with the word there
• Communication Skills Workshop Series: Communicate Like a Pro: Think like a...

Interprofessional Grand Rounds: Student Hotspotting Team 2016-2017, Caroline Komanecky, Peter Sacci, Danielle Mcfadden, Nuriya Neumann, Michaela Scotten, Melissa Murphy

Department of Occupational Therapy Posters and Presentations

No abstract provided.

Utilization Of Care By Infants With Neonatal Abstinence Syndrome In Delaware, Michele K. Savin, Msn, Nnp-Bc

College of Nursing Faculty Papers & Presentations

From 1999-2013, the nationwide incidence of neonatal abstinence syndrome (NAS) due to maternal drug use rose from 1.5/1000 to 6/1000 hospital births. There is a dearth of information regarding what happens to these children when they are discharged. The purpose of this Practice Inquiry Project is to utilize existing Delaware Medicaid data to retrospectively explore the utilization of services and gaps in care for the infant with NAS in the first year of life. Key findings include less than expected well child visits and immunizations along with higher hospital re-admission rates. This represents missed opportunities for care, also demonstrating the …

A Word From The Writing Center (July 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Grammar tip: affect vs effect
• Opportunity for online writing workshop for scientists

Jefferson Digital Commons Quarterly Report: April-June 2017, Daniel G. Kipnis, Msi, Kelsey Duinkerken, Msi, James Copeland, Libt

Jefferson Digital Commons Reports

For Full-Text access download report.

Jefferson Digital Commons Quarterly Report: April-June 2017

The Jefferson Digital Commons had another very busy quarter with assets being deposited from across the enterprise.

• Total number of assets deposited this quarter: 371
• Total downloads for this quarter: 113,261(April 10, 2017 highest download count: 1,763)
• 7,500 different institutions accessed content in the JDC Asset with the most downloads this quarter: 2017 issue of Inside Out
• Countries visiting the JDC this quarter: 196

Below are highlighted assets that were added to the inventory along with more feedback from researchers that continue to arrive from around the globe …

The Effects Of C5-Substituted 2,4-Diaminoquinazolines On Selected Transcript Expression In Spinal Muscular Atrophy Cells., Cinsley Gentillon, Andrew J Connell, Ryan W Kirk, Matthew E R Butchbach

Department of Pediatrics Faculty Papers

C5-substituted 2,4-diaminoquinazolines (2,4-DAQs) ameliorate disease severity in SMA mice. It is uncertain, however, that these compounds increase SMN protein levels in vivo even though they were identified as activators of the SMN2 promoter. These compounds also regulate the expression of other transcripts in neuroblastoma cells. In this study, we investigate the mechanism by which the 2,4-DAQs regulate the expression of SMN2 as well as other targets. D156844, D158872, D157161 and D157495 (RG3039) increased SMN2 promoter-driven reporter gene activity by at least 3-fold in NSC-34 cells. These compounds, however, did not significantly increase SMN2 mRNA levels in type II SMA fibroblasts …

A Delayed H3k27me3 Accumulation After Dna Replication Of Embryonic Stem Cells Opens Chromatin For Lineage Specific Transcription Factors To Bind And Initiate Differentiation, Jingli Cai, Svetlana Petruk, Robyn Sussman, Sina K. Kovermann, Samantha Mariani, Bruno Calabretta, Steven B Mcmahon, Hugh W. Brock, Lorraine Iacovitti, Alexander Mazo

Department of Neuroscience Faculty Papers

Introduction

Pluripotent stem cells (PSCs) have been useful to generate differentiated progenies for cell replacement therapy, and disease models. The Parkinson’s Disease (PD) field was arguably one of the first to have embraced the promise of stem cells. However, regardless of the differentiation protocols used, cultures and grafts continue to contain multiple cell types with midbrain dopamine (mDA) neural progenitors (NPs) and neurons representing only a fraction of total cells in the dish or graft. During cell differentiation, recruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional programs, which is impeded by condensed …

A Word From The Writing Center (June 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing tip: Purpose of semicolons and colons
• Tips on preparing posters

Interdisciplinary Learning Project, Demetrius H. Bagley, Md, Maryann Sonzogni, Rn, Bsn, Bridget Weissinger, Cst, Kelly A. Healy, Md

Department of Urology Faculty Papers

Description

With a 20 year history, we have implemented a multifaceted IPE program for members of the urology team. These include urologists, both faculty and community, residents, medical students, nurses, nurse practitioners, physician assistants, medical technicians/assistants and administrative/ clerical personnel with patient contact. The program was designed with three components: a yearly symposium for all, and journal club(JC) and lectures for non-physicians. Participation is on a voluntary, noncompensatory basis. Outcome measures include routine anonymous participant feedback via questionnaire.

Results

The programs were very positively received. Limiting obstacles were also observed. Initially too many papers were assigned in the Journal club. …

Aboriginal Urban Design For Health, Kate Clark, Mpa, Kirby Broadnax, Antionette Carroll, Jonathan Cha, Naomi Doerner, Allie Kast, Matthew Kennedy, Michael Mendez, Pascale C. Annoual, Carrie Martin, Wendall Nicholas

College of Population Health Lectures, Presentations, Workshops

Montreal’s Aboriginal population is growing rapidly, yet the community lacks a culturally safe and holistic health service center that is accessible to all Aboriginal people. On Friday, June 2, 2017 The Montreal Urban Aboriginal Health Centre (MUAHC) joined forces with Next City & Concordia University to co-create a 7-minute pitch for a $7,000 prize through the Vangaurd Conference Big Idea Challenge. An interdisciplinary team of 8 conference attendees worked with MUAHC leadership to design a short-term solution that would be a step in the right direction towards MUAHC’s goal to build a fully functioning and independent health center dedicated …

Firing Up Instead Of Burning Out: Tales From The Front Line Of The Cake Committee, Britainy Stephens, Msw, Lsw, Lora Rhodes, Msw, Lsw, Alison Petok, Msw, Lcsw, Gregory Garber, Msw, Lcsw

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

This presentation will focus on an underutilized model of supportive care that can help bring back some of the human moments that can often be lost in delivering supportive oncology care. Handling the often complicated issues that arise in oncology care can take a toll on social workers and our oncology co-workers in other disciplines. In oncology care, especially in an outpatient setting, social workers often fulfill the role of emotional support not just for our patients but also for other oncology professionals. Though we are not employed to act as such, we dually assume the position of therapist and …

Gathering Qualitative Feedback And Demonstrating Value For An Institutional Repository (Ir), Daniel G. Kipnis, Msi

Academic Commons and Scott Memorial Library Staff Papers and Presentations

Objective:

To gather qualitative feedback demonstrating value for assets discovered in institutional repository from researchers across the globe.

Poster presented at 117th Medical Library Association Annual Conference in Seattle, Washington.

Health Sciences Libraries To The Rescue: Bolstering The Library's Role With Repository And Publishing Services, Daniel G. Kipnis, Msi

Academic Commons and Scott Memorial Library Staff Papers and Presentations

Panel discussion sponsored by Bepress showcasing repositories and how they can increase the visibility and relevance of the health sciences library by providing crucial services. Attendees will come away with a concrete sense of how they can identify needs on campus, reach out to various stakeholders, and get support from strategic partners.

Effect Of Oral Iron Repletion On Exercise Capacity In Patients With Heart Failure With Reduced Ejection Fraction And Iron Deficiency: The Ironout Hf Randomized Clinical Trial., Gregory D Lewis, Rajeev Malhotra, Adrian F Hernandez, Steven E Mcnulty, Andrew Smith, G Michael Felker, W H Wilson Tang, Shane J Larue, Margaret M Redfield, Marc J Semigran, Michael M Givertz, Peter Van Buren, David J Whellan, Kevin J Anstrom, Monica R Shah, Patrice Desvigne-Nickens, Javed Butler, Eugene Braunwald

Department of Medicine Faculty Papers

Importance: Iron deficiency is present in approximately 50% of patients with heart failure with reduced left ventricular ejection fraction (HFrEF) and is an independent predictor of reduced functional capacity and mortality. However, the efficacy of inexpensive readily available oral iron supplementation in heart failure is unknown.

Objective: To test whether therapy with oral iron improves peak exercise capacity in patients with HFrEF and iron deficiency.

Design, Setting, and Participants: Phase 2, double-blind, placebo-controlled randomized clinical trial of patients with HFrEF (

Interventions: Oral iron polysaccharide (n = 111) or placebo (n = 114), 150 mg twice daily for 16 weeks. …

A Word From The Writing Center (May 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Grammar writing tip on ZOMBIE nouns!
• Keep Reading with BrowZine

Conference Posters Archived In The Jefferson Digital Commons, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

The Jefferson Digital Commons has archived over 680 conference posters. Here are some of the most recent additions to the collection:

• Evaluating Value-Based Frameworks Used for Relapsed or Refractory Multiple Myeloma Regimens: ICER Report, ASCO Value Framework, and NCCN Evidence Blocks
• Looking Beyond the Traditional: Integrating a New Curriculum Design into an Immersion Practicum Evaluation Tool
• Infection Prevention and Control in Baccalaureate Nursing Education: Identifying Content, Teaching Strategies and Gaps
• Book Club at Intern Orientation to Help Frame Professional Identity

And many more posters!

Socioeconomic Status And Stroke Outcome, Sophia Dang, Jonathan C. Li, Kimon Bekelis, Md, Stavropoula Tjoumakaris, Md

Sigma Xi Student Research Day

Introduction

• International studies find socioeconomic status (SES) to be predictive of functional impairment after stroke.^1,2
• Lower socioeconomic status (LSE) is associated with increased severity of stroke onset, higher incidence of risk factors, and worse outcomes.³
• We sought to confirm the predictive significance of SES on acute ischemic stroke patient outcomes at a large urban, U.S. stroke center.

Image-Guided High-Dose Rate Intracavitary Brachytherapy In The Treatment Of Medically Inoperable Early-Stage Endometrioid Type Endometrial Adenocarcinoma, Scott E. Jordan, Md, Ida Micaily, Md, Enrique Hernandez, Md, J. Stuart Ferriss, Md, Curtis T. Miyamoto, Md, Facr, Shidong Li, Phd, Bizhan Micaily, Md

Division of Internal Medicine Faculty Papers & Presentations

To report the experience with high dose rate, image guided intracavitary brachytherapy in the treatment of medically inoperable, early stage endometrial cancer.

Poster presented at:

American Brachytherapy Society Annual Meeting April 20-22, 2017 in Boston MA.

Jefferson College Of Population Health Capstones New To The Jefferson Digital Commons, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

A new batch of capstone presentations from the Jefferson College of Population Health have been loaded in the Jefferson Digital Commons:

MPH Capstone Presentations:

• Borders and Blood Pressure: Identifying the Association of Acculturation with Hypertension Diagnoses Among Hispanic-American Immigrants
• Partnerships to Improve Community Health (PICH) Initiative on Nutrition in Wilmington, DE: An Assessment of Fruit and Vegetable Consumption
• Perceptions of Living with Chronic Illness as Type 2 Diabetic Transgender Adults
• Addressing Obesity in the Early Head Start Community Through Environmental and Educational Means (Pilot Program)
• Screening for Adolescent Alcohol and Other Drug Use by Jefferson Providers: Methods, Barriers and …

Jefferson Digital Commons Quarterly Report (January – March 2017) Now Available, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

The Jefferson Digital Commons quarterly report for January-March 2017 is now available. The JDC got off to a great start in 2017 with over 300 new assets added, including the first Global Research Day hosted at Jefferson, a variety of Grand Rounds, podcasts, posters, and continued feedback from users from around the world. View the report to learn more.

Jefferson Digital Commons Quarterly Report: January-March 2017, Daniel G. Kipnis, Msi, Kelsey Duinkerken, Msi, James Copeland, Libt

Jefferson Digital Commons Reports

Quarterly report includes highlights of assets added to the JDC along with feedback from researchers.

The Use Of Quiet Books With People With Late Stage Dementia: A Case Study, Monique Chabot, Otd, Otr/L, Clipp, Caps, Cla, Jaime Galaton, Mot, Otr/L

Department of Occupational Therapy Posters and Presentations

Discussion of the use of Quiet Books as a method to provide sensory stimulation to people with late stage dementia to reduce agitation and combativeness with activities of daily living. Supporting literature for the use of sensory stimulation with people with dementia is also highlighted.

Poster presented at AOTA 2017 Annual Conference in Philadelphia PA and POTA 2016 Annual Conference

A Word From The Writing Center (April 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing Tip: Punctuation
• Organizing your Research using a citation manager
• Writing Café hours

Neonatal Implications Of Substance Use Treatment During Pregnancy, Michele K. Savin, Msn, Nnp-Bc

College of Nursing Faculty Papers & Presentations

I am writing in response to “Pharmacologic Treatment of Opioid Addiction During Pregnancy” by Keough and Fantasia (2017). The article nicely compares and summarizes the use of methadone and buprenorphine to treat substance use in pregnant women. I was dismayed, however, by the sections regarding neonatal considerations and breastfeeding, which contained some problematic assertions and some inaccurate conclusions.