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Full-Text Articles in Medicine and Health Sciences

Temporal Changes In The Levels Of Gamma-Aminobutyric Acid In The Brain Of The Cockroach, Leucophaea Maderae, Jonathan Newton Sep 1995

Temporal Changes In The Levels Of Gamma-Aminobutyric Acid In The Brain Of The Cockroach, Leucophaea Maderae, Jonathan Newton

Masters Theses & Specialist Projects

Circadian rhythms have been shown to exist in all studied species and play an important role in their survival. The cockroach is an excellent model organism in which to study circadian systems because of the wealth of background information regarding both its anatomy and circadian system. Clock activity measured electrophysiologically in the cockroach system is 180 degrees out of phase with locomotor activity, with the maximum neural output occurring in the morning, twelve hours prior to the onset of locomotor activity. This inverse relationship of locomotor and neural activity suggests that the clock output may be inhibitory. In vertebrates, the …


Site Directed Mutagenesis Of A Putative Protease Cleavage Site Within The 105 Kilodation Protein Of Southern Bean Mosaic Virus, Jingyu Shi Aug 1995

Site Directed Mutagenesis Of A Putative Protease Cleavage Site Within The 105 Kilodation Protein Of Southern Bean Mosaic Virus, Jingyu Shi

Masters Theses & Specialist Projects

There are four open reading frames (ORF) in three positive-sense translational phases of Southern Bean Mosaic Virus (SBMV). ORF2 codes for a 105 KDa polyprotein which is proposed to be autocatalytically cleaved into smaller functional proteins. Amino acid sequence homology between the SBMV and poliovirus, foot and mouth disease virus, and cowpea mosaic virus reveal that SBMV has a similar genomic organization to picornaviruses with a conserved order: Vpg (Viral protein, genome-linked )-protease-replicase. Two Gln-Ser (QS) amino acid pairs within the 105 KDa polyprotein, C75= 930-936, C60= 1305-1310, are proposed to be the cleavage sites based on 1) similar structural …


Antibody Response To Trypanosoma Cruzi During The Course Of Infection In Mice Held At Elevated Environmental Temperature, Lianyong Gao Aug 1995

Antibody Response To Trypanosoma Cruzi During The Course Of Infection In Mice Held At Elevated Environmental Temperature, Lianyong Gao

Masters Theses & Specialist Projects

It has been demonstrated that changes in environmental temperature can influence the resistance of mice to Trypanosoma cruzi (the causative agent of Chagas' disease in humans) infection. This increased resistance is not only reflected by decreased parasitemias and increased longevity but also by enhanced parasite-specific and nonspecific immune responsiveness in infected mice. The antibody response to heterologous antigen has been demonstrated to be greatly enhanced in infected mice held at elevated temperature. However, the parasite-specific antibody response was reported to be lower in infected mice maintained at 36°C than at room temperature (RT) during early stage of infection, although it …


Military Recreation Programs: Their Role In Quality Of Life Of United States' Service Men And Women And Their Families, Michael Gorham Aug 1995

Military Recreation Programs: Their Role In Quality Of Life Of United States' Service Men And Women And Their Families, Michael Gorham

Masters Theses & Specialist Projects

This thesis was designed to determine the importance of military recreation programs in improving the quality of life of United States service men and women. The study utilized a survey conducted on Fort Campbell, Kentucky, in the Spring of 1995. The results were analyzed individually and as a group. The findings were that military recreation programs play an important role in the quality of life of United States service men and women and their families. These findings were supported by the review of related literature and results from the survey which showed that 70% of the respondent's "Agreed" or "Strongly …


The Relationship Between Vision And Athletic Performance, Steven Richard Wininger Aug 1995

The Relationship Between Vision And Athletic Performance, Steven Richard Wininger

Masters Theses & Specialist Projects

In today's competitive world of athletics it is not uncommon to discover a few athletes actively involved in some form of vision enhancement motivated by the promise that the exercises will improve their athletic performance. A review of past and present literature in the area of sports vision revealed that these athletes are performing exercises based upon a very weak scientific foundation. Most of the research investigating the relationship between vision and athletic performance has been plagued by flawed methodology, as well as extremely low numbers of subjects. The purpose of this study was to test for any relationship between …


The Effect Of Dietary Supplemented Vitamin E And Selenium On Experimental Chagas' Disease, Brenda Bennett Aug 1995

The Effect Of Dietary Supplemented Vitamin E And Selenium On Experimental Chagas' Disease, Brenda Bennett

Masters Theses & Specialist Projects

Dietary supplementation with increased levels of vitamin E can enhance the immune system of C3HeB/FeJ mice to enable many of them to survive an otherwise lethal dose of Trypanosoma cruzi, the causative agent of Chagas' disease. To study the role of diet on the course of experimental Chagas' disease, C3HeB/FeJ mice were fed pelleted, synthetic food containing no vitamin E and selenium, 800 IU/kg vitamin E, 2 ppm selenium, or food containing 800 IU/kg vitamin E plus 2 ppm selenium. Mice on synthetic food were compared to control mice fed a commonly used Purina rodent chow # 5001. After diet …


The Relationship Between Risk For Drug Abuse And Meaning In Life, Paul Turner Jul 1995

The Relationship Between Risk For Drug Abuse And Meaning In Life, Paul Turner

Masters Theses & Specialist Projects

Drug abuse continues to be one of the most significant problems in the United States today. Attempts to understand drug abuse have produced numerous multidimensional prevention and treatment models. These models have resulted in the identification of psychological, social and biological risk factors related to drug abuse. In this study, the risk for drug abuse was assessed in 311 college students. A questionnaire was developed to measure risk. The questionnaire assessed risk for abuse predicted by the following factors: academic performance, coping and psychological health, religiosity, family and peer drug use, and the individual's past and current drug use. Based …


Factors Which Predict The Initiation And Use Of Alcohol In Rural Adolescents, Charlotte Swint Apr 1995

Factors Which Predict The Initiation And Use Of Alcohol In Rural Adolescents, Charlotte Swint

Masters Theses & Specialist Projects

The purpose of this research was to determine whether a selected group of factors are significant when trying to predict the use of alcohol by adolescents who live in rural areas. This research is important because most of the studies concerning drug and alcohol use in adolescents have focused on adolescents who live in urban areas. The results of such studies may not be generalizable to rural populations. The factors investigated included the following: availability of alcohol, peer influence, parental influence, tobacco use, gender, and grade level. These factors were chosen based on their inclusion in four prominent theories regarding …


Health Attitude Changes As A Result Of Participating In A Worksite Prenatial Education Program, Vickie Gibson Apr 1995

Health Attitude Changes As A Result Of Participating In A Worksite Prenatial Education Program, Vickie Gibson

Masters Theses & Specialist Projects

The purpose of this study was to determine whether differences in health beliefs exist between participants attending worksite prenatal education classes and participants receiving only prenatal education self-help materials. A multiple treatment study was performed on a sample of convenience of 169 women enrolled in Fruit of the Loom's worksite prenatal education program. Group 1 subjects received class and materials while Group 2 subjects received materials only. Study participants were asked to complete an 18-item Likert scale questionnaire prior to enrolling in the program and again upon completion. Sixty-two subjects completed both the pre- and posttest questionnaires. Analysis of covariance …


Site-Directed Mutagenesis Of Southern Bean Mosaic Virus (Cowpea Strain): In Search Of A Viral Protease, Alan Simmons Jan 1995

Site-Directed Mutagenesis Of Southern Bean Mosaic Virus (Cowpea Strain): In Search Of A Viral Protease, Alan Simmons

Masters Theses & Specialist Projects

The second and largest open reading frame within the southern bean mosaic virus (SBMV) genome encodes a 105 kDa polyprotein. Following translation, the polyprotein is cleaved to liberate various proteins necessary for SBMV replication. The elements within polyproteins of the picornavirus superfamily members have a conserved order: Vpg (viral protein, genome-linked)-protease-replicase. Amino acid sequence homologies indicate that the 105 kDa protein of SBMV contains a replicase very similar to those identified in polyproteins of the picorna-like viruses. The presence of a VPg covalently attached to the 5' end of the SBMV genome further suggests that SBMV may be considered a …