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MCV/Q, Medical College of Virginia Quarterly

Annual McGuire Lecture Series

Publication Year

Articles 1 - 26 of 26

Full-Text Articles in Medicine and Health Sciences

Surgical Treatment Of The Upper Extremity In Rheumatoid Arthritis, Charles L. Mcdowell Jan 1974

Surgical Treatment Of The Upper Extremity In Rheumatoid Arthritis, Charles L. Mcdowell

MCV/Q, Medical College of Virginia Quarterly

All surgical procedures designed to preserve or improve function in the extremities, whether in rheumatoid arthritis or not, must consider the functional emphasis of the upper extremity as compared to the lower extremity. The upper extremity has, as its primary goal, mobility and prehension, whereas in the lower extremity, stability is the most important goal, mobility the next in order of importance, and prehension the least important. For example, the feet fulfill a need for stability with very little requirement for prehension, but the hand is more an instrument for prehension and there is less need to consider stability. I …


Diagnostic Concordance Of Serological Tests For Antiglobulin Antibodies, Marion Waller Jan 1974

Diagnostic Concordance Of Serological Tests For Antiglobulin Antibodies, Marion Waller

MCV/Q, Medical College of Virginia Quarterly

Rheumatoid factors are present in a variety of disease states and in normal persons, usually in low titer. High titers of rheumatoid factors are almost exclusively associated with rheumatoid arthritis.


Modern Immunology: Cells And Molecules, Franklin Mullinax Jan 1974

Modern Immunology: Cells And Molecules, Franklin Mullinax

MCV/Q, Medical College of Virginia Quarterly

In this presentation I shall discuss 1) some historical highlights n the field of immunology; 2) the molecules of immunity, particularly the immunoglobulins; and 3) the cells of immunity, particularly the immunocytes. This presentation may provide a background for subsequent articles.


Surgical Care Of The Lower Extremity In Rheumatoid Arthritis, Roby C. Thompson Jan 1974

Surgical Care Of The Lower Extremity In Rheumatoid Arthritis, Roby C. Thompson

MCV/Q, Medical College of Virginia Quarterly

One of the most important things for the physician to recognize in referring a patient to the orthopedic surgeon for treatment of rheumatoid arthritis is the goal of surgical correction. The primary goal in surgical treatment of diseased joints in the lower extremity is relief of pain. Some pain-free patients have such severe deformities that a surgical procedure may be undertaken in order to improve and restore function, accepting certain calculated risks; however, to improve function surgically in a pain-free joint requires complete and full understanding on the part of the patient as well as the physician.


Introduction, Robert Irby Jan 1974

Introduction, Robert Irby

MCV/Q, Medical College of Virginia Quarterly

The 45th Annual McGuire Lecture Series has been devoted to the subject of Immunology and the Rheumatic Diseases. In this two-day period, 22 outstanding physicians in the field of immunology and rheumatology brought an up-to-date overall concept in the field of rheumatic diseases. Subjects included not only aspects of pathogenesis but also modern laboratory methods in the diagnosis of various connective tissues diseases. The remedial surgical approaches for prevention of pain and disability in rheumatoid arthritis were discussed from a practical viewpoint.


Recent Advances In Synovial Fluid Analysis, Duncan S. Owen Jr. Jan 1974

Recent Advances In Synovial Fluid Analysis, Duncan S. Owen Jr.

MCV/Q, Medical College of Virginia Quarterly

Synovial fluid analysis is a frequently ignored examination except in suspected cases of septic conditions. It has been shown that it is an extremely valuable procedure in making rapid and accurate diagnoses in many types of joint diseases.


Summary Of Papers Presented At The 45th Annual Mcguire Lecture Series, Robert Irby Jan 1974

Summary Of Papers Presented At The 45th Annual Mcguire Lecture Series, Robert Irby

MCV/Q, Medical College of Virginia Quarterly

It is the purpose of this presentation to quickly review some of the important points of the papers which were presented at the 45th Annual McGuire Lecture Series on the subject of immunology and rheumatic diseases.


Surgery In Rheumatoid Arthritis: General Indications And Philosophic Considerations, R. S. Bryan Jan 1974

Surgery In Rheumatoid Arthritis: General Indications And Philosophic Considerations, R. S. Bryan

MCV/Q, Medical College of Virginia Quarterly

In summary, orthopedic surgery has much to offer the rheumatoid patient, particularly if the proper patient is chosen at the proper time. The advent of the total joint replacements, now in its infancy, gives renewed hope for the salvage of many derelicts and for the prevention of the severe disabilities and deformities which were all too frequent in the past.


Still's Disease In Adults, William M. Edwards, Stephen R. Koller, Michael J. Miller Jan 1974

Still's Disease In Adults, William M. Edwards, Stephen R. Koller, Michael J. Miller

MCV/Q, Medical College of Virginia Quarterly

In 1897, Dr. George F. Still described 22 children with a form of chronic joint disease which differed from rheumatic fever. Twelve of these children had a syndrome characterized by glandular and splenic enlargement which, with a characteristic fever pattern, rash, and arthritis, has become known as Still's disease. Subsequent investigators have described patients over age 16 presenting with similar signs and symptoms suggesting that this syndrome is not specific for children. We recently studied a patient in whom the diagnosis of adult onset Still's disease was made.


Advancing Technology Of Clinical Laboratory Practice, George Z. Williams Jan 1973

Advancing Technology Of Clinical Laboratory Practice, George Z. Williams

MCV/Q, Medical College of Virginia Quarterly

In spite of the temporary antitechnology attitude of a portion of our society, the future will be an era of automated technology. Buckminster Fuller has reviewed the progress of industrial technology and points out that continuing scientific advances are inevitable and that technical applications will provide more equitable distribution of wealth, more time, more opportunity for education and intellectual pursuits.


Meaningful Toxicology, Robert V. Blanke Jan 1973

Meaningful Toxicology, Robert V. Blanke

MCV/Q, Medical College of Virginia Quarterly

The scope of toxicology, therefore, may extend from the study of a single element such as lead to a complex, chemically uncharacterized substance such as snake venom; from an overdose of heroin to the effects of long-term exposure to low levels of pesticides on anticonvulsant therapy. For the purpose of this discussion, we shall narrow the limits of the broad field of toxicology considerably, but it is important to be aware of the breadth and depth to which toxicology may at times extend.


The Modernization Of The Autopsy: Application Of Ultrastructural And Biochemical Methods To Human Disease, Benjamin F. Trump, Jon M. Valigorsky, Jane H. Dees, Wolfgang J. Mergner, Kook M. Kim, Raymond T. Jones, Robert E. Pendergrass, Joel Garbus, Julio H. Garcia, Jesus E. Viloria, Junichi Tanaka, Hannu Kalimo, Yoshinari Kamijyo, R. Adams Cowley Jan 1973

The Modernization Of The Autopsy: Application Of Ultrastructural And Biochemical Methods To Human Disease, Benjamin F. Trump, Jon M. Valigorsky, Jane H. Dees, Wolfgang J. Mergner, Kook M. Kim, Raymond T. Jones, Robert E. Pendergrass, Joel Garbus, Julio H. Garcia, Jesus E. Viloria, Junichi Tanaka, Hannu Kalimo, Yoshinari Kamijyo, R. Adams Cowley

MCV/Q, Medical College of Virginia Quarterly

The autopsy has provided, and still provides, the stimulus for many attempts to reproduce disease in experimental animal models. This approach has become increasingly difficult, however, in the case of human disease, principally shock. The study of some pathological states in animal models requires testing in several species and final confirmation in man before this knowledge can be applied to living patients. In our studies the application of cell biology techniques at autopsy has permitted the generation of new hypotheses which are more amenable to further exploration in experimental models and can be more precisely related to human disease.


The Value Of Chemical Screening Profiles On Blood, Seymour Bakerman Jan 1973

The Value Of Chemical Screening Profiles On Blood, Seymour Bakerman

MCV/Q, Medical College of Virginia Quarterly

Chemical screening profiles on blood specimens are designed to yield information that may lead to new and additional clinical diagnoses, to revision of clinically established diagnoses, to confirmed impressions of the physician and to following the course of diseases during a patient's hospitalization. Screening profiles on blood are designed to indicate disease of the liver, kidney, heart, striated muscle and other organs; they may be helpful in the diagnosis of anemia, diabetes mellitus, gout, congestive heart failure, osteomalacia, and hyperlipidemia, hyperparathyroidism and other diseases. When these screening profiles were first introduced, there was widespread skepticism among physicians as to their …


Multitest Screening In Hematology, Charles L. Johnston Jr. Jan 1973

Multitest Screening In Hematology, Charles L. Johnston Jr.

MCV/Q, Medical College of Virginia Quarterly

The concept of multitest screening for hematological disorders is not necessarily a new one. Implementation of such ideas has recently become possible, for the automated electronic instruments performing sequential multiple analyses within very short periods of time are a very significant advancement in the technology of the hematology laboratory. It must be emphasized, however, that the value of such instrumentation lies not only in the rapidity, but also in the accuracy and precision as well as the number and nature of the tests performed. While the data on samples have been reported on individual patients three and a half years …


Utilization Of Blood And Its Products, Robert D. Langdell Jan 1973

Utilization Of Blood And Its Products, Robert D. Langdell

MCV/Q, Medical College of Virginia Quarterly

At present time there are a number of blood components that are more suitable for transfusion purposes than is whole blood. In order to make maximum use of blood, it is necessary that there be close cooperation between the blood bank personnel and those responsible for patient care.


Laboratory Aspects Of Venereal Disease, Mario R. Escobar Jan 1973

Laboratory Aspects Of Venereal Disease, Mario R. Escobar

MCV/Q, Medical College of Virginia Quarterly

Introducing the laboratory aspects of venereal diseases, I would like to define the criteria according to which certain infectious diseases are considered to be "sexually transmitted." The expression "sexually transmitted disorder" is less weighted with moral overtones than the term "venereal" and may therefore be more acceptable to both medical practitioners and the general public.


Unique Characteristics And Implications Of Individual Health Profiles, George Z. Williams Jan 1973

Unique Characteristics And Implications Of Individual Health Profiles, George Z. Williams

MCV/Q, Medical College of Virginia Quarterly

During the era of the prescientific medicine, people were divided into two categories: those who were sick and those who were not sick. Physicians found it necessary to establish criteria to differentiate the ill and separate them according to symptoms and signs characteristic of classifiable diseases. Because of preoccupation with disease, the concept of the "normal" versus the pathological, as two opposite and definable conditions, was inevitable in the absence of scientific knowledge of human chemistry and physiology. This concept has carried over into the present era of scientific medicine.


Pitfalls In Unqualified Acceptance Of Laboratory Data, Myrton F. Beeler Jan 1973

Pitfalls In Unqualified Acceptance Of Laboratory Data, Myrton F. Beeler

MCV/Q, Medical College of Virginia Quarterly

One can never be absolutely certain that any single laboratory report is correct. As a general rule, therefore, do not undertake potentially serious action on behalf of any patient solely because of a single laboratory report. This is especially important if the result is unexpected or not in harmony with the rest of the clinical information available.


Haa (Hb Ag) Evaluation-State Of The Art, Ali A. Hossaini, Mario R. Escobar Jan 1973

Haa (Hb Ag) Evaluation-State Of The Art, Ali A. Hossaini, Mario R. Escobar

MCV/Q, Medical College of Virginia Quarterly

In conclusion, this study supports the claim that the RIA is the most sensitive of all assay methods for detection of HB Ag in use today. Because of the inability to verify the presence of HB Ag in those sera positive by RIA alone, however, this claim must be taken only at face value. Further studies are needed to confirm the specificity of these positive reactions.


Evaluation Of Prepackaged "Kits", Rex B. Conn Jr. Jan 1973

Evaluation Of Prepackaged "Kits", Rex B. Conn Jr.

MCV/Q, Medical College of Virginia Quarterly

Prepackaged laboratory kits for performing diagnostic procedures are frequently the most suitable alternative in the selection of laboratory methods, especially in the physicians' offices and small laboratories. Because of the previous lack of governmental regulations covering the manufacture of kits, many kits now on the market do not perform adequately and may produce misleading results. Each laboratory must evaluate each type of kit before it is put into routine use. This evaluation should include a review of published experimental data, comparison of results using the kit to results using a reference method and an experimental evaluation of the kit in …


Microbial Monitoring, Harry P. Dalton Jan 1973

Microbial Monitoring, Harry P. Dalton

MCV/Q, Medical College of Virginia Quarterly

The need for monitoring both areas for alteration in microbial flora, which may result in invasion or adverse effect on internal organs of the host, has been an accepted scientific fact of modern medicine for years. Questions remain, however, on how much monitoring needs to be done. What areas of the patients and the environment should be tested, and what are the practical uses of the results of such monitoring? Before attempting to answer these questions, let me give you an overview of how microbial monitoring has been used at the Medical College of Virginia hospitals and other institutions to …


Quality Control In The Office Laboratory, Joseph H. Riddick Jr. Jan 1973

Quality Control In The Office Laboratory, Joseph H. Riddick Jr.

MCV/Q, Medical College of Virginia Quarterly

First, how can the quality of the office laboratory be assured and documented? Second, how can this information be disseminated to legislators and the general public? The first is an easily solved technical problem toward which this paper is directed. The second and probably the most difficult is a media problem beyond the scope of a technical journal.


Contents Jan 1973

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1973, Volume Nine, Number Four.


Newer Techniques In Clinical Cytology: Aspiration Biopsy And Brushing Cytology, William J. Frable Jan 1973

Newer Techniques In Clinical Cytology: Aspiration Biopsy And Brushing Cytology, William J. Frable

MCV/Q, Medical College of Virginia Quarterly

Since its introduction some twenty years ago the Papanicolaou technique for cervical-vaginal cytology has had a tremendous impact on the detection of precancerous lesions and in situ cancer in the female genital tract. It has forced the clinician and pathologist to study the "early lesions" of cancer, particularly in the female genital tract and has brought about a better understanding of their biology. Cytology has over the years been extended to other areas, particularly the respiratory tract. Two recent areas of emphasis are the thin-needle aspiration biopsy and direct brushing of mucosal surfaces through the various fiber optic scopes now …


Commercial And Reference Laboratories, George J. Carroll Jan 1973

Commercial And Reference Laboratories, George J. Carroll

MCV/Q, Medical College of Virginia Quarterly

In summary, there are now in existence many good commercial and reference laboratories. I would use those laboratories with which you are most familiar, where you know the staff, those which can demonstrate reasonable speed in testing and can assure good quality testing and control at what you feel is a reasonable cost to the patient.


Introduction, George P. Vennart Jan 1973

Introduction, George P. Vennart

MCV/Q, Medical College of Virginia Quarterly

This issue of the Medical College of Virginia Quarterly is devoted to the 44th Annual McGuire Lecture Series held in March 1973, under the auspices of the Division of Clinical Pathology, Department of Pathology, and the Department of Continuing Education.