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Illawarra Health and Medical Research Institute

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Full-Text Articles in Medicine and Health Sciences

Effectiveness Of Quality Incentive Payments In General Practice (Equip-Gp): A Study Protocol For A Cluster-Randomised Trial Of An Outcomes-Based Funding Model In Australian General Practice To Improve Patient Care, Gregory Peterson, Grant Russell, Jan Radford, Nicholas Arnold Zwar, Danielle Mazza, Simon Eckermann, Judy Mullan, Marijka Batterham, Athena Hammond, Andrew D. Bonney Jan 2019

Effectiveness Of Quality Incentive Payments In General Practice (Equip-Gp): A Study Protocol For A Cluster-Randomised Trial Of An Outcomes-Based Funding Model In Australian General Practice To Improve Patient Care, Gregory Peterson, Grant Russell, Jan Radford, Nicholas Arnold Zwar, Danielle Mazza, Simon Eckermann, Judy Mullan, Marijka Batterham, Athena Hammond, Andrew D. Bonney

Illawarra Health and Medical Research Institute

Background There is international interest in whether improved primary care, in particular for patients with chronic or complex conditions, can lead to decreased use of health resources and whether financial incentives help achieve this goal. This trial (EQuIP-GP) will investigate whether a funding model based upon targeted, continuous quality incentive payments for Australian general practices increases relational continuity of care, and lessens health-service utilisation, for high-risk patients and children. Methods We will use a mixed methods approach incorporating a two-arm pragmatic cluster randomised control trial with nested qualitative case studies. We aim to recruit 36 general practices from Practice-Based Research …


Application Of The Integrated Behavioral Model To Oral Self‐Care Behavior Of Community‐Dwelling Middle‐Aged And Older People In Taiwan, Mu-Hsing Ho, H.C. Chang, Yen-Kuang Lin, Victoria Traynor, Hung-Huey Tsai, Kathleen Buckwalter, Megan F. Liu, Chia-Chi Chang Jan 2019

Application Of The Integrated Behavioral Model To Oral Self‐Care Behavior Of Community‐Dwelling Middle‐Aged And Older People In Taiwan, Mu-Hsing Ho, H.C. Chang, Yen-Kuang Lin, Victoria Traynor, Hung-Huey Tsai, Kathleen Buckwalter, Megan F. Liu, Chia-Chi Chang

Illawarra Health and Medical Research Institute

Objectives This study evaluated the Integrated Behavioral Model and examined oral self‐care behavior of community‐dwelling middle‐aged and older people. Design A cross‐sectional design was used. Sample Purposive sampling was employed to recruit middle and older age community‐dwelling individuals, with research locations in public health centers in northern Taiwan. Measurements Structured questionnaires comprised: participant demographics, oral health literacy, oral self‐care attitude, self‐efficacy, intention, and behavior, and significant others' perceptions and beliefs as well as environmental constraints. The Model verification was evaluated by path analysis. Results Two hundred and sixty‐three participants (N = 263) completed the questionnaire survey. Results identified significant direct …


Evaluation Of A Brief Intervention Within A Stepped Care Whole Of Service Model For Personality Disorder, Elizabeth A. Huxley, Kate L. Lewis, Adam Coates, Wayne Borg, Caitlin Miller, Michelle L. Townsend, Brin F. S Grenyer Jan 2019

Evaluation Of A Brief Intervention Within A Stepped Care Whole Of Service Model For Personality Disorder, Elizabeth A. Huxley, Kate L. Lewis, Adam Coates, Wayne Borg, Caitlin Miller, Michelle L. Townsend, Brin F. S Grenyer

Illawarra Health and Medical Research Institute

Background Although there is growing evidence that stepped models of care are useful for providing appropriate, person centered care, there are very few studies applied to personality disorders. A brief, four session, psychological treatment intervention for personality disorder within a whole of service stepped care model was evaluated. The intervention stepped between acute emergency crisis mental health services and longer-term outpatient treatments. Methods Study 1 used service utilization data from 191 individuals referred to the brief intervention at a single community health site in a metropolitan health service. Proportions of individuals retained across the intervention and the referral pathways accessed …


Improved Social Interaction, Recognition And Working Memory With Cannabidiol Treatment In A Prenatal Infection (Poly I:C) Rat Model, Ashleigh L. Osborne, Nadia Solowij, Ilijana Babic, Xu-Feng Huang, Katrina Weston-Green Jan 2017

Improved Social Interaction, Recognition And Working Memory With Cannabidiol Treatment In A Prenatal Infection (Poly I:C) Rat Model, Ashleigh L. Osborne, Nadia Solowij, Ilijana Babic, Xu-Feng Huang, Katrina Weston-Green

Illawarra Health and Medical Research Institute

Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment, including learning, memory and attention deficits. Antipsychotic drugs are limited in their efficacy to improve cognition; therefore, new therapeutic agents are required. Cannabidiol (CBD), the non-intoxicating component of cannabis, has anti-inflammatory, neuroprotective and antipsychotic-like properties; however, its ability to improve the cognitive deficits of schizophrenia remains unclear. Using a prenatal infection model, we examined the effect of chronic CBD treatment on cognition and social interaction. Time-mated pregnant Sprague-Dawley rats (n=16) were administered polyinosinic-polycytidilic acid (poly I:C) (POLY; 4 mg/kg) or saline (CONT) at gestation day 15. Male offspring …


Heme Consumption Reduces Hepatic Triglyceride And Fatty Acid Accumulation In A Rat Model Of Nafld Fed Westernized Diet, Soon Yew Tang, Irwin Kee M. Cheah, Pei Ern Ng, Aina Hoi, Andrew M. Jenner Jan 2014

Heme Consumption Reduces Hepatic Triglyceride And Fatty Acid Accumulation In A Rat Model Of Nafld Fed Westernized Diet, Soon Yew Tang, Irwin Kee M. Cheah, Pei Ern Ng, Aina Hoi, Andrew M. Jenner

Illawarra Health and Medical Research Institute

Studies have identified that serum-free hemoglobin subunits correlate positively with the severity of nonalcoholic fatty liver disease (NAFLD). However, the role of hemoglobin in the development of NAFLD remains unclear. In the present study, a rat model of NAFLD was developed, using a westernized diet high in saturated fat and refined sugar. Since a "westernized" diet is also high in red meat, we tested the effect of hemoglobin as a dietary source of heme in our model. Sprague-Dawley rats were fed ad libitum for 4 weeks either control diet (7% fat), westernized diet (WD, 18% fat + 1% cholesterol), hemoglobin …


Novel Behavioural Characteristics Of The Appswe/Ps1Δe9 Transgenic Mouse Model Of Alzheimer's Disease, David Cheng, Warren Logge, Jac Kee Low, Brett Garner, Tim Karl Jan 2013

Novel Behavioural Characteristics Of The Appswe/Ps1Δe9 Transgenic Mouse Model Of Alzheimer's Disease, David Cheng, Warren Logge, Jac Kee Low, Brett Garner, Tim Karl

Illawarra Health and Medical Research Institute

In order to better understand animal models of Alzheimer's disease, novel phenotyping strategies have been established for transgenic mouse models. In line with this, the current study characterised male APPxPS1 transgenic mice on mixed C57BL/6JxC3H/HeJ background for the first time for social recognition memory, sensorimotor gating, and spatial memory using the cheeseboard test as an alternative to the Morris water maze. Furthermore, locomotion, anxiety, and fear conditioning were evaluated in transgenic and wild type-like animals. APPxPS1 males displayed task-dependent hyperlocomotion and anxiety behaviours and exhibited social recognition memory impairments compared to wild type-like littermates. Spatial learning and memory, fear conditioning, …