Medicine and Health Sciences Commons^™

Molecular Serotype-Specific Identification Of Non-Type B Haemophilus Influenzae By Loop-Mediated Isothermal Amplification, Chika Takano, Yoko Kuramochi, Mitsuko Seki, Dong Wook Kim, Daisuke Omagari, Mari Sasano, Bin Chang, Makoto Ohnishi, Eun Jin Kim, Kazumasa Fuwa, Paul E. Kilgore, Tomonori Hoshino, Satoshi Hayakawa

Department of Pharmacy Practice

In children, the incidence of pneumococcal meningitis has decreased since the introduction of pneumococcal conjugate vaccine (PCV7 and PCV13). However, since the introduction of the vaccine, developed countries have seen the emergence of non-PCV13 serotypes. However, invasive pneumococcal disease (IPD) caused by PCV13-targeted serotypes still represents an important public health problem in resource-limited countries. To develop a rapid, simple, and cost-effective assay to detect serotypes of Streptococcus pneumoniae, we developed a novel loop-mediated isothermal amplification (LAMP) assay based on the sequences available for the 13 capsular types that are included in PCV13: 1, 3, 4, 5, 6 A, 6B, …

Finding Latent Groups In Observed Data: A Primer On Latent Profile Analysis In Mplus For Applied Researchers, Sarah L. Ferguson, E. Whitney G. Moore, Darrell M. Hull

Kinesiology, Health and Sport Studies

The present guide provides a practical guide to conducting latent profile analysis (LPA) in the Mplus software system. This guide is intended for researchers familiar with some latent variable modeling but not LPA specifically. A general procedure for conducting LPA is provided in six steps: (a) data inspection, (b) iterative evaluation of models, (c) model fit and interpretability, (d) investigation of patterns of profiles in a retained model, (e) covariate analysis, and (f) presentation of results. A worked example is provided with syntax and results to exemplify the steps.

Summary Of The International Patient Safety Conference, June 28-29, 2019, Kathmandu, Nepal, Deepak C. Bajracharya, Kshitij Karki, Chhiring Yangjen Lama, Rajesh Dhoj Joshi, Shankar Man Rai, Sudhakar Jayaram, Amit Tomer, John Zervos, Mohammad Imran Khan, Arjun Sapkota, Madan Kumar Upadhyaya, Paul E. Kilgore

Department of Pharmacy Practice

Globally, medical errors are associated with an estimated $42 billion in costs to healthcare systems. A variety of errors in the delivery of healthcare have been identified by the World Health Organization and it is believed that about 50% of all errors are preventable. Initiatives to improve patient safety are now garnering increased attention across a range of countries in all regions of the world. From June 28--29, 2019, the first International Patient Safety Conference (IPSC) was held in Kathmandu, Nepal and attended by over 200 healthcare professionals as well as hospital, government, and non-governmental organization leaders. During the conference, …

A Community-Based Survey To Assess Knowledge, Attitudes, Beliefs And Practices Regarding Herpes Zoster In An Urban Setting, Nour A. Baalbaki, Joseph P. Fava, Melanie Ng, Ezinwanne Okorafor, Asad Nawaz, Wesley Chiu, Abdulbaset Salim, Raymond Cha, Paul E. Kilgore

Department of Pharmacy Practice

Introduction: In the USA, nearly one in three people will experience herpes zoster (HZ) in their lifetime. Underserved communities may be at even higher risk due to several factors, including access to healthcare, education, and co-morbid conditions. The purpose of this study was to investigate current knowledge, attitudes, beliefs and practices (KABP) relative to HZ and HZ vaccines in a large urban city.

Methods: A cross-sectional KABP survey was conducted via in-person interview among 381 participants aged ≥ 50 years in Detroit, MI, USA, from June to August 2018. Survey results were stratified into two groups [< 60 and ≥ 60 years of age (YO)] for comparison.

Results: Of the …

The Relationship Of Motivational Climates, Mindsets, And Goal Orientations To Grit In Male Adolescent Soccer Players, Erin Albert, Trent A. Petrie, E. Whitney G. Moore

Kinesiology, Health and Sport Studies

Across a variety of domains, such as in academics and in the military, grit is a significant predictor of performance, even after controlling for dimensions of innate ability. However, little is known about how grit develops or the psychosocial factors that may contribute to its presence (i.e. motivational climates, mindsets, and goal orientations). Although sport is a natural context in which to examine grit, both as a predictor and an outcome, few studies have done so. Thus, within the framework of achievement motivation theory, we examined the relationships of the perceived motivational climate created by coaches (task-involving vs. ego-involving), athletes’ …

Strategies To Increase Athletes' Transformational Leadership Behaviors During Strength And Conditioning Sessions, Valerie Smith, E. Whitney G. Moore

Kinesiology, Health and Sport Studies

Often, leadership is presumed to naturally result from athletic experiences. However, leadership behaviors require practice. Strength and conditioning coaches (SCCs) can provide opportunities for all athletes to practice transformational leadership behaviors, which can increase team cohesion and performance. This article reviews athlete leadership, including leadership roles and four transformational leadership behaviors (idealized influence, inspirational motivation, individualized consideration, and intellectual stimulation). Then, daily strategies SCCs can incorporate into training to foster athletes’ transformational leadership are presented. Followed by strategies for larger, rotating leadership experiences. These strategies can work with athletes across age, gender, and competitive level.

Increasing Collegiate Strength And Conditioning Coaches' Communication Of Training Performance And Process Goals With Athlete, E. Whitney G. Moore, Alessandro Quartiroli, Rebecca Zakrajsek, Morgan Eckenrod

Kinesiology, Health and Sport Studies

The purpose of this paper is to present information about goal setting and how strength and conditioning coaches (SCCs) can incorporate goal setting strategies in their training of athletes. This paper presents an overview of outcome, performance, and process goals, and the SMAART framework. Strategies a SCC can utilize are presented to illustrate how to increase the effectiveness of the performance and process goals that informed the program periodization and feedback provided by the SCC. This paper aims to start bridging the gap between SCCs familiarity with goal setting and incorporation of this mental strategy into their communication with athletes …

Considering Physical Well-Being, Self-Perceptions, And Support Variables In Understanding Youth Academic Achievement, Erin E. Centeio, Cheryl L. Somers, E. Whitney G. Moore, Alex Garn, Noel Kulik, Jeffrey Martin, Bo Shen, Nate Mccaughtry

Kinesiology, Health and Sport Studies

The purpose of this study was to examine the relation between measures of students’ physical well-being and self-perception and their academic achievement. Specifically, we look at students’ social support for physical activity, physical activity perceptions, self-concept, self-efficacy, health behaviors, and cardiorespiratory fitness (as measured by the progressive aerobic cardiovascular endurance run [PACER] test). Students (n = 697 fifth graders) were surveyed at the beginning of the school year. A two-group path analysis revealed notable relationships between the predictor variables and proximal and distal outcomes, with some paths moderated by sex. One relationship that was significant for both sexes was …

Development Of A Novel Loop-Mediated Isothermal Amplification Method To Detect Guiana Extended-Spectrum (Ges) Β-Lactamase Genes In Pseudomonas Aeruginosa, Chika Takano, Mitsuko Seki, Dong Wook Kim, Humphrey Gardner, Robert E. Mclaughlin, Paul E. Kilgore, Kazunari Kumasaka, Satoshi Hayakawa

Department of Pharmacy Practice

Infections caused by multidrug-resistant Pseudomonas aeruginosa in hospitalized patients are often fatal, and nosocomial infections caused by Guiana extended-spectrum (GES) β-lactamase-producing strains are of growing concern. Several genotypes of the GES β-lactamase gene (bla_GES) include a single missense mutation, a change from G to A at nucleotide position 493 (G_493A) that changes glycine to serine; the mutant enzyme exhibits carbapenemase activity. Rapid and reliable identification of drug-resistance is important in clinical settings; however, culture methods remain the gold standard. Conventional and real-time PCR cannot identify carbapenemase-producing genotypes, and direct DNA sequencing is essential. We established …

Evaluation Of An Educational Campaign To Improve The Conscious Consumption Of Recreationally Caught Fish, Corey A. Krabbenhoft, Susan Manente, Donna R. Kashian

Environmental Science and Geology Faculty Research Publications

Consumption guidelines are a common way of improving conscious consumption behaviors in areas where game fish are known to contain contaminants. However, guideline information can be difficult to distribute, and effectiveness difficult to measure. To increase the distribution and effectiveness of guideline information for the Detroit River, an educational campaign was launched in 2010, which included distribution of pamphlets with consumption information, posting of permanent signs at popular fishing locations, and hiring River Walkers to personally communicate with anglers. In 2013 and 2015, we conducted in-person surveys of active shoreline anglers to determine the effectiveness of education and outreach efforts. …

Understanding Diabetes Through Pathway Analysis Evaluation, London Cavaletto

Research Opportunities for Engineering Undergraduates (ROEU) Program 2018-19

Metabolic disorders affect many people and identifying significantly perturbed biological processes in a metabolic disease can provide valuable insight into the disease’s mechanisms. Evaluating the proposed Metabolic Pathway Analysis Method (RAMP) will enable us to reliably use it to identify significantly perturbed metabolic pathways that could help identify disease mechanisms and potential therapy targets or disease bio-markers of a metabolic disorder.

Communication Of Deaf People Based On Myoware Muscle Sensor, Mohamad Ataya

Research Opportunities for Engineering Undergraduates (ROEU) Program 2018-19

The current project aims to create a product that enhances communication of deaf people. The developed product has the following features:

• a muscle sensor that transcribes sign language into actual letters

• a voice detector that translates speech into actual words

• the ability to receive and send emergency alerts.

Comparison Of Emla And Diclofenac On Reduction Of Pain And Phlebitis Caused By Peripheral Iv Catheter: A Randomized-Controlled Trial Study, Faezeh Babaieasl, Hossein Y. Yarandi, Seyedehtanaz Saeidzadeh, Motahareh Kheradmand

Nursing Faculty Research Publications

Peripheral venous catheters (PVC) are often used to provide hydration, medications, and blood products when the length of therapy is expected to be less that one week. Pain and phlebitis are frequent complications of PVC. Diclofenac and EMLA have been used to minimize these adverse effects, however, conflicting results have been reported regarding which has better outcomes. This double-blind, randomized controlled trial was conducted to compare the efficacy of EMLA and Diclofenac (TDP) in attenuating PVC pain and phlebitis. The inpatient setting was chosen because of the higher frequency of PVC insertions, allowing for a sufficient sample size. One hundred …