Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Animals (1)
- Apoptosis (1)
- Candida albicans (1)
- Candidiasis (1)
- Combined Modality Therapy (1)
-
- Cutaneous (1)
- Delayed (1)
- Female (1)
- Ficusin (1)
- G-Protein-Coupled (1)
- Humans (1)
- Hypersensitivity (1)
- Hypersensitivity, Delayed (1)
- Immune Tolerance (1)
- Immunosuppression (1)
- Inflammation (1)
- Interleukin-10 (1)
- Knockout (1)
- Lymphoma (1)
- Lymphoma, T-Cell, Cutaneous (1)
- Male (1)
- Mice (1)
- Mice, Knockout (1)
- PUVA Therapy (1)
- Platelet Activating Factor (1)
- Platelet Membrane Glycoproteins (1)
- Psoriasis (1)
- Receptors (1)
- Receptors, G-Protein-Coupled (1)
- Signal Transduction (1)
- Publication
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Platelet-Activating Factor Is Crucial In Psoralen And Ultraviolet A-Induced Immune Suppression, Inflammation, And Apoptosis., Peter Wolf, Dat X Nghiem, Jeffrey P Walterscheid, Scott Byrne, Yumi Matsumura, Yasuhiro Matsumura, Cora Bucana, Honnavara N Ananthaswamy, Stephen E Ullrich
Platelet-Activating Factor Is Crucial In Psoralen And Ultraviolet A-Induced Immune Suppression, Inflammation, And Apoptosis., Peter Wolf, Dat X Nghiem, Jeffrey P Walterscheid, Scott Byrne, Yumi Matsumura, Yasuhiro Matsumura, Cora Bucana, Honnavara N Ananthaswamy, Stephen E Ullrich
Journal Articles
Psoralen plus UVA (PUVA) is used as a very effective treatment modality for various diseases, including psoriasis and cutaneous T-cell lymphoma. PUVA-induced immune suppression and/or apoptosis are thought to be responsible for the therapeutic action. However, the molecular mechanisms by which PUVA acts are not well understood. We have previously identified platelet-activating factor (PAF), a potent phospholipid mediator, as a crucial substance triggering ultraviolet B radiation-induced immune suppression. In this study, we used PAF receptor knockout mice, a selective PAF receptor antagonist, a COX-2 inhibitor (presumably blocking downstream effects of PAF), and PAF-like molecules to test the role of PAF …
Caring Minds, University Of Texas Health Science Center At Houston School Of Nursing
Caring Minds, University Of Texas Health Science Center At Houston School Of Nursing
Caring Minds
- Welcome from Dean Patricia Starck
- The Face of Health Care
- Leading Technology
- School of Nursing Collaborates to Initiate Texas Medical Center’s First Digital Repository
- Nursing Research, A Growing Field
- Nursing in the Wake of the Storm
- Profile: Huaping Liu, RN, PhD, Dean and Associate Professor, School of Nursing at Peking Union Medical College
- Newsbrief: Planning for the Future with a New Doctor of Nursing Practice Program in Fall 2006
- Newsbrief: Fast Track Nursing Program Gives Students a Speedy Start
- Profile: Susan Bankston, RN, BSN, Psychiatric Nursing, Currently enrolled in the MSN to DSN track
- Newsbrief: University of Texas Health Services …
Dose-Response Characteristics Of Methylphenidate On Locomotor Behavior And On Sensory Evoked Potentials Recorded From The Vta, Nac, And Pfc In Freely Behaving Rats, Pamela B Yang, Alan C Swann, Nachum Dafny
Dose-Response Characteristics Of Methylphenidate On Locomotor Behavior And On Sensory Evoked Potentials Recorded From The Vta, Nac, And Pfc In Freely Behaving Rats, Pamela B Yang, Alan C Swann, Nachum Dafny
Journal Articles
BACKGROUND: Methylphenidate (MPD) is a psychostimulant commonly prescribed for attention deficit/hyperactivity disorder. The mode of action of the brain circuitry responsible for initiating the animals' behavior in response to psychostimulants is not well understood. There is some evidence that psychostimulants activate the ventral tegmental area (VTA), nucleus accumbens (NAc), and prefrontal cortex (PFC).
METHODS: The present study was designed to investigate the acute dose-response of MPD (0.6, 2.5, and 10.0 mg/kg) on locomotor behavior and sensory evoked potentials recorded from the VTA, NAc, and PFC in freely behaving rats previously implanted with permanent electrodes. For locomotor behavior, adult male Wistar-Kyoto …