Medicine and Health Sciences Commons^™

Glutamatergic Plasticity In Medial Prefrontal Cortex And Ventral Tegmental Area Following Extended-Access Cocaine Self-Administration, Behnam Ghasemzadeh, Preethi Vasudevan, Chad Giles, Anthony Purgianto, Chad Seubert, John R. Mantsch

Biomedical Sciences Faculty Research and Publications

Glutamate signaling in prefrontal cortex and ventral tegmental area plays an important role in the molecular and behavioral plasticity associated with addiction to drugs of abuse. The current study investigated the expression and postsynaptic density redistribution of glutamate receptors and synaptic scaffolding proteins in dorsomedial and ventromedial prefrontal cortex and ventral tegmental area after cocaine self-administration. After 14 days of extended-access (6 h/day) cocaine self-administration, rats were exposed to one of three withdrawal regimen for 10 days. Animals either stayed in home cages (Home), returned to self-administration boxes with the levers withdrawn (Box), or underwent extinction training (Extinction). Extinction training …

Recommendations For Sexuality Education For Early Adolescents, Kristin Haglund

College of Nursing Faculty Research and Publications

Objective: To determine community support and identify appropriate learning methodologies, parameters of delivery, and intervention content.

Design: Qualitative descriptive study in which participants were interviewed in a semistructured format. Data were analyzed thematically.

Setting: An urban pediatric primary care clinic from which youths and parents were recruited.

Participants: Ten youths, 10 parents, and 10 community members. Community members included professional and laypersons who had experience in working with early adolescents or in working with children of any age on sexuality issues. Overall, most participants were female (67%) and African American (67%).

Results: Descriptions of early adolescents ’ knowledge of sexuality, …