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Full-Text Articles in Medicine and Health Sciences
Total Antioxidant Capacity As An Aging Marker In Egyptian Patients With Alzheimer Disease, Ahmed A. Sonbol, Amr S. Shalaby, Dalia H. Abou-Elela, Mariam A. Fouaad, Rawhia H. El-Edel
Total Antioxidant Capacity As An Aging Marker In Egyptian Patients With Alzheimer Disease, Ahmed A. Sonbol, Amr S. Shalaby, Dalia H. Abou-Elela, Mariam A. Fouaad, Rawhia H. El-Edel
Menoufia Medical Journal
Objective This study aimed to evaluate the total antioxidant capacity (TAC) as an aging marker in patients with Alzheimer disease (AD). Background AD is a neurodegenerative disorder that affects elderly and is the most common type of dementia. Reactive oxygen species is a major risk factor of Alzheimer. Oxidative stress, the most important factor in the pathogenesis of Alzheimer, occurs when reactive oxygen species and reactive nitrogen species increase and/or antioxidant defense system decreases. TAC is a marker of DNA oxidation. These data will explain pathogenesis and prevention and help in the treatment of AD. Patients and methods This study …
A Comparative Study On The Effect Of Aging On The Hippocampal Ca1 Area Of Male Albino Rat, Abeer E. El-Mehi, Fatma El-Nabawia A El-Safti, Rasha R. Selima, Wael B. El-Kholoy
A Comparative Study On The Effect Of Aging On The Hippocampal Ca1 Area Of Male Albino Rat, Abeer E. El-Mehi, Fatma El-Nabawia A El-Safti, Rasha R. Selima, Wael B. El-Kholoy
Menoufia Medical Journal
Objectives This work aimed to study the effect of aging on the structure of the hippocampus in the adult and aged male albino rats. Background Dementia is one of the most important problems nowadays. Aging is associated with learning and memory impairments. Aging is the progressive accumulation of changes with time that are associated with or responsible for the ever-increasing susceptibility to disease and death, which accompanies advancing age. The hippocampal formation is one of the most common brain areas affected by aging in both humans and other mammalian species. Materials and methods Eighteen male albino rats were divided into …