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Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Description And Practical Application Of The Physiologic Distribution Of 3’-Deoxy-3’-[18f]Fluorothymidine In Companion Animals, Joshua Alan Rowe
Description And Practical Application Of The Physiologic Distribution Of 3’-Deoxy-3’-[18f]Fluorothymidine In Companion Animals, Joshua Alan Rowe
Doctoral Dissertations
Access to positron emission tomography (PET), and more recently PET combined with computed tomography (PET/CT), is increasing in veterinary medicine. This molecular imaging technology allows clinicians to map biological functions within patients based on the distribution and selective uptake of specialized positron-emitting radiopharmaceuticals. Although most clinical studies utilize 2-deoxy-2-[18F]fluoro-Dglucose (18FDG), a versatile but relatively nonspecific tracer that interrogates the energy metabolism of tissues, there is a growing need to establish reference values for alternative or adjunct tracers in veterinary species. Among these is 3’-deoxy-3’- [18F]fluorothymidine (18FLT), a thymidine analog that selectively accumulates …
Management Of Multiple Intracranial Granular Cell Tumors In A Golden Retiever, Pichanun Linharattanaruksa, Pakthorn Lewchalermwong, Muhammad Khalid, Kannika Siripattarapravat
Management Of Multiple Intracranial Granular Cell Tumors In A Golden Retiever, Pichanun Linharattanaruksa, Pakthorn Lewchalermwong, Muhammad Khalid, Kannika Siripattarapravat
The Thai Journal of Veterinary Medicine
A 9-year-old, neutered female Golden Retriever was presented with generalized seizures, abnormal mentation and ataxia. Magnetic resonance imaging revealed five separated masses at the left dorsal meninges, caudodorsal cerebellum, right cerebral cortex, olfactory lobe and right occipital lobe. Right rostrotentorial craniectomy was performed to debulk the tumor at the right cerebral cortex. On the basis of histopathological evaluation, the mass was diagnosed as GCTs. Immunohistochemistry of the mass demonstrated immunopositivity for vimentin and immunonegativity for GFAP, NSE, Desmin, S-100, CK14, CK8/18, CK19, and Ki67. Postoperative neurological deficits were resolved, but six months later neurological signs recurred with higher frequency of …
Outcomes Of Spatially Fractionated Radiotherapy (Grid) For Bulky Soft Tissue Sarcomas In A Large Animal Model, Michael W. Nolan, Tracy L. Gieger, Alexander A. Karakashian, Mariana N. Nikolova‑Karakashian, Lysa P. Posner, Donald M. Roback, Judith N. Rivera, Sha Chang
Outcomes Of Spatially Fractionated Radiotherapy (Grid) For Bulky Soft Tissue Sarcomas In A Large Animal Model, Michael W. Nolan, Tracy L. Gieger, Alexander A. Karakashian, Mariana N. Nikolova‑Karakashian, Lysa P. Posner, Donald M. Roback, Judith N. Rivera, Sha Chang
Physiology Faculty Publications
GRID directs alternating regions of high- and low-dose radiation at tumors. A large animal model mimicking the geometries of human treatments is needed to complement existing rodent systems (eg, microbeam) and clarify the physical and biological attributes of GRID. A pilot study was undertaken in pet dogs with spontaneous soft tissue sarcomas to characterize responses to GRID. Subjects were treated with either 20 Gy (3 dogs) or 25 Gy (3 dogs), delivered using 6 MV X-rays and a commercial GRID collimator. Acute toxicity and tumor responses were assessed 2, 4, and 6 weeks later. Acute Radiation Therapy Oncology Group grade …
The Effects Of Reward-Based Training On The Behavioral Assessment Of The Domestic Dog, Shelby Vandergraff, Shelby K. Vandergraff
The Effects Of Reward-Based Training On The Behavioral Assessment Of The Domestic Dog, Shelby Vandergraff, Shelby K. Vandergraff
Murray State Theses and Dissertations
Contrary to popular belief, pet overpopulation is caused more by owners failing to keep their dog than with accidental or intentional breeding (Moulton et al., 1991). Factors related to relinquishment have been researched, and concluded that behavioral problems are the most reoccurring reasons observed (Bailey, 1992; Miller at al., 1996; Patronek et al., 1996; Serpell, 1966; Salman et al., 1998, 2000; Scarlett et al, 1999; New et al., 2000; Shore et al., 2003, 2005; Mondelli 2004, Blackwell et al., 2008). When animals are relinquished to the shelter, the likelihood of the animal being euthanized increases. The purpose of this research …
Development Of Leptospiral Outer Membrane Protein-Based Dot-Elisa Assays And Immunoprofiling For Diagnosis Of Acute Canine Leptospirosis, Vamshi Krishna Sriram, Siju Joseph, Ambily Ramachandran, Mini Mangattumuruppel
Development Of Leptospiral Outer Membrane Protein-Based Dot-Elisa Assays And Immunoprofiling For Diagnosis Of Acute Canine Leptospirosis, Vamshi Krishna Sriram, Siju Joseph, Ambily Ramachandran, Mini Mangattumuruppel
Turkish Journal of Veterinary & Animal Sciences
The present study was carried out to evaluate outer membrane protein (OMP)-based relatively simple dot-ELISA assays for the diagnosis of acute canine leptospirosis and to identify the differential expression of leptospiral OMPs for identifying the markers of acute infection, if any. Among 91 canine serum samples screened, 63 samples were found to be positive by MAT. All the samples were tested by OMP-based IgM and IgG dot ELISAs. The sensitivities of IgM and IgG dot ELISA in comparison to MAT (titer: ≥1:400) were found to be 100%, whereas the specificities were found to be 89.71% and 45.31%, respectively. IgM and …