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Full-Text Articles in Medicine and Health Sciences

An Otopathological Assessment Of Dogs Exposed To Excessive Dietary Fluoride And/Or Suspected Water Borne Toxins, Barbara Ann Hannah Apr 1987

An Otopathological Assessment Of Dogs Exposed To Excessive Dietary Fluoride And/Or Suspected Water Borne Toxins, Barbara Ann Hannah

Masters Theses

In 1970, a once very productive Allegan, Michigan dog kennel began experiencing a rash o£ unexplained perinatal deaths and reproductive anomalies in Shetland pups. Anomalies including cleft palate and lip, kinked tails, twisted feet and convulsions immediately before death plagued the neonates. The adult dogs were reported to have tooth mottling, exostoses and auditory and vestibular problems.

Because the dogs had been on high fluoride diets and because the kennel well water was suspected of harboring toxins, a group of 20 Shetland dogs was used to try to find if there was any correlation between the reproductive problems and the …


The Effects Of Insulin On Hepatic Glucocorticoid Receptor Content In The Diabetic Rat, Jeffrey John Yourick Apr 1983

The Effects Of Insulin On Hepatic Glucocorticoid Receptor Content In The Diabetic Rat, Jeffrey John Yourick

Masters Theses

The streptozotocin-induced diabetic rat liver was analyzed for glucocorticoid receptor (GCR) content by a saturation and Scatchard analysis. A preliminary study was performed on the stabilization of the cytoplasmic GCR in a frozen cytosol preparation. The addition of 10% glycerol (V/V), 10 mM sodium molybdate, and 0.2 mg/ml trypsin inhibitor resulted in an approximate 20% sparing of GCR content upon freezing.

The hepatic GCR content of diabetic rats was significantly decreased from a control level of 0.1667 ± 0.0142 pmol/mg protein to 0.1094 ± 0.007 pmol/mg protein. Insulin replacement therapy to the diabetic rat dramatically increased the hepatic GCR content. …


The Effects Of Prostaglandin E2 On The Healing Processes Of Rat Perforated Tympanic Membranes, Diane Sue Saylor Apr 1983

The Effects Of Prostaglandin E2 On The Healing Processes Of Rat Perforated Tympanic Membranes, Diane Sue Saylor

Masters Theses

Prostaglandin E2 (PGE2) was topically administered to perforated rat tympanic membranes in an attempt to facilitate regrowth of the membranes. Every 24 hours for the first four postperforation days, two groups of tympanic membranes were processed and examined histologically for differences between PGE2 treated and control animals.

At 24 hours postperforation granulocyte infiltration at the perforation site was greater in the test animals. By 48 hours blood clots were larger in PGE2 treated animals. Finally, the epithelium was thinner in test animals than in control animals at 96 hours.

Slight tendencies for the test animals …


Temporal Pattern Of Gluconeogenesis In Diabetic And Non-Diabetic Chinese Hamsters, John P. Ofenstein Aug 1982

Temporal Pattern Of Gluconeogenesis In Diabetic And Non-Diabetic Chinese Hamsters, John P. Ofenstein

Masters Theses

Gluconeogenesis is a normal physiological response of an individual to low blood glucose levels by which proteins are utilized in order to synthesize new glucose. Gluconeogenic rates in diabetic and normal Chinese hamsters were measured, on four different occasions over a 24 hour period, by injecting a radio-labelled precursor (14C-lactate) into the animals. Then blood was tested for incorporation of the label into glucose. In the fed state, gluconeogenesis shows a circadian change in nondiabetic hamsters as well as in diabetic hamsters, with the diabetic hamsters showing a significantly greater gluconeogenic rate than the non-diabetic hamsters for every …


Glucocorticoid Receptors In Liver Cytosol Of Adrenalectomized Diabetic And Nondiabetic Chinese Hamsters, Richard E. Gibson Apr 1980

Glucocorticoid Receptors In Liver Cytosol Of Adrenalectomized Diabetic And Nondiabetic Chinese Hamsters, Richard E. Gibson

Masters Theses

The binding characteristics of glucocorticoid receptors in the liver cytosol of Chinese hamsters of the BE, BD (diabetic), and AV (nondiabetic) lines were studied and compared using a charcoal adsorption technique and 3H-dexamethasone. High affinity receptors(Kd ≃ 3 x 10-9 M) were found with concentrations of 180 fmoles/mg protein in the nondiabetic and 260 fmoles/mg protein in the diabetic hamsters. Behavior of the receptor-steroid complex in 5 to 20% sucrose gradients of low and high salt concentrations (0.0 and 0.3 M KCl) and the competitive binding of other steroids were consistent with findings for rat liver glucocorticoid …


Time-Related Changes In Rat Androgen Binding Protein Following A Sterilizing Dose Of 3-Chloro-1, 2-Propanediol, Shirley J. Stein Aug 1979

Time-Related Changes In Rat Androgen Binding Protein Following A Sterilizing Dose Of 3-Chloro-1, 2-Propanediol, Shirley J. Stein

Masters Theses

Androgen binding protein (ABP) is produced by the Sertoli cell, regulated by FSH and androgens, secreted into the testicular fluid, and transported into the caput epididymis where it is thought to play a role in sperm maturation. In this study, the response of ABP to a lesion created chemically by administration of a single, oral 60 mg/kg dose of alpha-chlorohydrin was examined in ninety day old male rats. Total testicular ABP content increased progressively for four days after treatment and there after declined whereas, epididymal ABP concentration decreased immediately. Serum testosterone showed no significant variation from controls, however, serum FSH …


An In Vitro Study Of The Effects Of 17Β Estradiol On A Possible Atherosclerotic-Causing Enzyme, Xanthine Oxidase, Peter E. Malo Aug 1978

An In Vitro Study Of The Effects Of 17Β Estradiol On A Possible Atherosclerotic-Causing Enzyme, Xanthine Oxidase, Peter E. Malo

Masters Theses

No abstract provided.


The Effects Of Body Size, Hair And Brown Adipose Tissue Upon Fever In The Rabbit, Reginald L. Dean Apr 1978

The Effects Of Body Size, Hair And Brown Adipose Tissue Upon Fever In The Rabbit, Reginald L. Dean

Masters Theses

No abstract provided.


The Effect Of Prostaglandins And Aspirin On Insulin Release From Isolated Normal Rat Islets, Barbara Ann Hopps Apr 1978

The Effect Of Prostaglandins And Aspirin On Insulin Release From Isolated Normal Rat Islets, Barbara Ann Hopps

Masters Theses

No abstract provided.


An Investigation Into The Nature Of Action Of The Hyperglycemic Factor Present In The Suprapharyngeal Ganglia Of Lumbricus Terrestris, Bruce M. Taylor Aug 1977

An Investigation Into The Nature Of Action Of The Hyperglycemic Factor Present In The Suprapharyngeal Ganglia Of Lumbricus Terrestris, Bruce M. Taylor

Masters Theses

No abstract provided.


Inhibition Of Gastric Secretion And Ulcer Formation By Lithium Chloride In The Rat, Thomas H. Adair Aug 1976

Inhibition Of Gastric Secretion And Ulcer Formation By Lithium Chloride In The Rat, Thomas H. Adair

Masters Theses

No abstract provided.


Progesterone And Cortisol In The Hamster: Their Role In Parturition, As Well As The Growth And Lactogenesis Of The Mammary Glands, Anne Christine Flook Apr 1975

Progesterone And Cortisol In The Hamster: Their Role In Parturition, As Well As The Growth And Lactogenesis Of The Mammary Glands, Anne Christine Flook

Masters Theses

No abstract provided.


Metabolic Abnormalities In Liver And Pancreas Of A Diabetic (Toronto-Kk) Strain Of Mouse, Michael Clayton Appel Aug 1973

Metabolic Abnormalities In Liver And Pancreas Of A Diabetic (Toronto-Kk) Strain Of Mouse, Michael Clayton Appel

Masters Theses

No abstract provided.


A Study Of Regulation Of Oxidative Metabolism By Substances Present In The Suprapharyngeal Ganglia And Ventral Nerve Cord In Lumbricus Terrestris, Mary Peremuh Aug 1973

A Study Of Regulation Of Oxidative Metabolism By Substances Present In The Suprapharyngeal Ganglia And Ventral Nerve Cord In Lumbricus Terrestris, Mary Peremuh

Masters Theses

No abstract provided.


The Influence Of Nicotine On The Effect Of Secretin On Gastric Secretion In The Rat And Dog, Donald H. Currie Aug 1973

The Influence Of Nicotine On The Effect Of Secretin On Gastric Secretion In The Rat And Dog, Donald H. Currie

Masters Theses

No abstract provided.


Thyroid And Ldh Activity In Coho Salmon From West Coast And Lake Michigan Regions, Robert A. Drongowski Dec 1972

Thyroid And Ldh Activity In Coho Salmon From West Coast And Lake Michigan Regions, Robert A. Drongowski

Masters Theses

No abstract provided.


Ovum Transport In Rabbits Injected With Prostaglandin E1 Or F, James Vernon Ellinger Dec 1972

Ovum Transport In Rabbits Injected With Prostaglandin E1 Or F2Α, James Vernon Ellinger

Masters Theses

No abstract provided.


Daily Patterns Of Oxygen Consumption In Limnodrilus Hoffmeisteri, Thomas Charles Beck Dec 1972

Daily Patterns Of Oxygen Consumption In Limnodrilus Hoffmeisteri, Thomas Charles Beck

Masters Theses

No abstract provided.


Peripheral Blood Changes In Canada Geese And The Reproductive Condition Of Three Michigan Flocks, William B. Potter Apr 1971

Peripheral Blood Changes In Canada Geese And The Reproductive Condition Of Three Michigan Flocks, William B. Potter

Masters Theses

No abstract provided.


In Vitro Hypothalamic Stimulation Of Fsh Synthesis And Release In Anterior Pituitaries From Five- And Twenty-Five-Day-Old Female Rats, James A. Dibbet Dec 1970

In Vitro Hypothalamic Stimulation Of Fsh Synthesis And Release In Anterior Pituitaries From Five- And Twenty-Five-Day-Old Female Rats, James A. Dibbet

Masters Theses

No abstract provided.


Immunological And Reproductive Responses In The Male Rat Following Challenge With Homologous Or Autologous Sperm, James M. Andress Dec 1970

Immunological And Reproductive Responses In The Male Rat Following Challenge With Homologous Or Autologous Sperm, James M. Andress

Masters Theses

No abstract provided.


The Biodegradability Of Detergents And The Effects Of Biodegradable Detergents Upon Root Elongation Of Certain Plants, Nancy Lou Bishop Aug 1970

The Biodegradability Of Detergents And The Effects Of Biodegradable Detergents Upon Root Elongation Of Certain Plants, Nancy Lou Bishop

Masters Theses

The effects of three biodegradable detergents upon root elongation of Cucumis sativus and Avena sativa was determined. All three detergents inhibit root elongation; the degree of inhibition depends on the brand of detergent and the species tested. Contact of the detergents with a sandy-loam results in reversal of inhibition of root elongation; the degree of reversal varies with detergent and species. However, reversal after 48 hours contact with soil does not appear to be due to degradation by microorganisms. Effects of aeration and of pH on test solutions are discussed.


The Role Of The Suprapharyngeal Ganglia Of Lumbricus Terrestris In Respiratory Metabolism, John D. Nelson Dec 1969

The Role Of The Suprapharyngeal Ganglia Of Lumbricus Terrestris In Respiratory Metabolism, John D. Nelson

Masters Theses

No abstract provided.


A Study Of Blood Constituent Levels And The Influence Of Certain Environmental Factors Upon Them In The Wild Mallard Duck, Christopher Louis Schatte Sep 1968

A Study Of Blood Constituent Levels And The Influence Of Certain Environmental Factors Upon Them In The Wild Mallard Duck, Christopher Louis Schatte

Masters Theses

No abstract provided.


The Effect Of Pregnancy And Lactation On Steroid-Induced Ulcers In The Rat, Paul A. Kelly Apr 1968

The Effect Of Pregnancy And Lactation On Steroid-Induced Ulcers In The Rat, Paul A. Kelly

Masters Theses

No abstract provided.


A Study Of Dietary Effects On Peripheral Blood Constituents Of The Female Mallard Under Estrogen Stimulation, Nickolias George Smyrnios Dec 1967

A Study Of Dietary Effects On Peripheral Blood Constituents Of The Female Mallard Under Estrogen Stimulation, Nickolias George Smyrnios

Masters Theses

No abstract provided.


Influence Of Some Stressors On Peripheral Blood Response To Estrogen Stimulation In The Female Mallard Duck, Morton S. Rickless Sep 1967

Influence Of Some Stressors On Peripheral Blood Response To Estrogen Stimulation In The Female Mallard Duck, Morton S. Rickless

Masters Theses

No abstract provided.


Nickelous Nitrate Hexahydrate And Its Effect On Reproduction In The Mouse, Marvin R. Guthaus Dec 1966

Nickelous Nitrate Hexahydrate And Its Effect On Reproduction In The Mouse, Marvin R. Guthaus

Masters Theses

No abstract provided.