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Articles 1 - 12 of 12
Full-Text Articles in Medicine and Health Sciences
Efficacy Of Probiotics Lactobacillus Rhamnosus Gg And Saccharomyces Boulardii In The Treatment Of Antibiotic-Associated Diarrhea And Clostridium Diffiicile-Associated Disease, Estie Klugmann
The Science Journal of the Lander College of Arts and Sciences
Antibiotic therapy may cause serious side effects. Two disturbing effects of antibiotic administration are antibiotic-associated diarrhea and Clostridium difficile-associated disorder. Antibiotic-associated diarrhea occurs as a direct result of the normal flora destruction due to the antibiotics - which do not discriminate against pathogens or healthy forms of bacteria. C. diff disorder also occurs as an indirect result of antibiotic administration, because the destruction of the normal flora prevents people from having healthy bacteria to prevent disease. There have been studies conducted to determine if replacing the destroyed normal flora with probiotics, or beneficial microorganisms will prevent or treat these conditions. …
Huntington's Disease And Its Effect On The Brain, Shaina Rivkin-Drizin
Huntington's Disease And Its Effect On The Brain, Shaina Rivkin-Drizin
The Science Journal of the Lander College of Arts and Sciences
Huntington's disease is a neurodegenerative disease that leads to gradual extensive brain damage, especially in the striatum and the cerebral cortex. Initial symptoms are cognitive difficulties, loss of motor contra and sudden mood imbalances. Cognitive function slowly declines into dementia, coupled with behavioral and psychiatric problems. Sufferers die within 20 years due to illness complications: a fall, pneumonia, or heart disease (Walker, 2007). This paper reviews the principle biological cause of the disease, its effect on the brain, diagnosis, and treatment.
What Is The Role Of Incretin Mimetics In The Treatment Of Type 2 Diabetes?, Isaac Silberstein
What Is The Role Of Incretin Mimetics In The Treatment Of Type 2 Diabetes?, Isaac Silberstein
The Science Journal of the Lander College of Arts and Sciences
Type 2 diabetes mellitus (DM) is an intricate disorder defined by insulin resistance, impaired insulin secretion, hyperglycemia, and both microvascular and macrovascular complications. Standard antidiabetic agents like metformin, insulin, sulfonylureas and thiazolidinediones are often insufficient at glucoregulation and do not address the decline in beta cell function that characterizes type 2 diabetes. Moreover, the adverse effects of some of these pharmaceuticals, such as hypoglycemia and weight gain, are disappointing and further limit their clinical utility. Research demonstrates that the actions of two potent incretins. Glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP), address these concerns as they stimulate beta …
Is There An Alternative Way Of Treating Drug Resistant Epilepsy? The Effects Of The Ketogenic Diet In Children With Intractable Epilepsy, Chaya M. Weinberg
Is There An Alternative Way Of Treating Drug Resistant Epilepsy? The Effects Of The Ketogenic Diet In Children With Intractable Epilepsy, Chaya M. Weinberg
The Science Journal of the Lander College of Arts and Sciences
Many children with epilepsy experience seizures that cannot be resolved with medication. Since surgical intervention is not always an option, the ketogenic diet (KD). a high fat, low carbohydrate and protein diet, offers a chance for seizure reduction and in some cases freedom from seizures and medication. Side effects do exist, although none are serious. Efficacy has been proven through many studies. The mechanism of the KD's effectiveness is still unknown, although several hypotheses exist, including the theory that ketone bodies themselves are anticonvulsant, and the hypothesis that glucose restriction stops seizures. Adenosine A1 receptors are also thought to have …
Are Oncolytic Viruses A Cure For Cancer? A Look At Reovirus, Adenovirus, And Hsv-1 In Cancer Treatment, Yehuda Rosenberg
Are Oncolytic Viruses A Cure For Cancer? A Look At Reovirus, Adenovirus, And Hsv-1 In Cancer Treatment, Yehuda Rosenberg
The Science Journal of the Lander College of Arts and Sciences
This paper aims to evaluate the option of utilizing Oncolytic Viruses as a viable treatment in fighting cancer. However, due to the broad nature of the subject, a more limited purview is necessary. With that in mind, the focus will be on a few of the more researched ones: Reovirus, Adenovirus, and HSV-1. In each case, we will examine what makes each of these potential options. This will include an examination of each one's tumor-specificity. Cancer and viral physiology will be discussed as necessary to examine the distinct protein expressions in tumor cells, so that the virus's method of battling …
The Common Allergic Mechanism Of Rhinitis And Asthma, Esther Feinstein
The Common Allergic Mechanism Of Rhinitis And Asthma, Esther Feinstein
The Science Journal of the Lander College of Arts and Sciences
Allergic rhinitis and asthma are closely linked diseases which are very prevalent within the population, affecting millions. They are both characterized by chronic airway inflammation. They are often present in the same patients and rhinitis is even considered an independent risk factor for asthma. Treating allergic rhinitis can reduce the severity of asthma. Mechanisms connecting the two have been researched for many years. Studies show that they have a similar allergic mechanism that is mediated by the same cells. The allergic inflammation is characterized by the presence of eosinophils and is mediated by T-helper type 2 lymphocytes. The circulation of …
Are Epidermal Barrier Defects Responsible For The Underlying Pathology Of Atopic Dermatitis?, Naomi Davis
Are Epidermal Barrier Defects Responsible For The Underlying Pathology Of Atopic Dermatitis?, Naomi Davis
The Science Journal of the Lander College of Arts and Sciences
Atopic dermatitis, often referred to as eczema, is a chronic inflammatory skin condition frequently seen in young children. It is a complex disease involving environmental factors, genetics and immune dysregulation. There is currently no cure with conflicting opinions from physicians regarding treatment and management. A clearer understanding of pathogenesis of atopic dermatitis can hopefully lead to new and improved treatment options for patients. Current evidence seems to support epidermal skin barrier defects as the cause of this disease. This paper seeks to investigate if this out-in hypothesis can be responsible as the sole pathogenesis of atopic dermatitis. To write this …
Complex Regional Pain Syndrome: A Review Of Current Treatments, Yosef Lewis
Complex Regional Pain Syndrome: A Review Of Current Treatments, Yosef Lewis
The Science Journal of the Lander College of Arts and Sciences
Complex Regional Pain Syndrome (CRPS) is a syndrome that develops infrequently in patients that experience a minor or severe trauma to a bodily extremity. CRPS has two subtypes; Type-I and II, both are clinically characterized by hyperalgesia. During its acute stage, CRPS hyperalgesia is clinically characterized by edema in the subcutaneous tissues of the epidermis, allodynia, and localized bone resorption. In the later chronic stage, hyperalgesia is aroused by the disregulation of blood flow to the extremity and permanent dystonic and trophic changes to the skin. Because the epidemiology and central causation of CRPS remains unknown until today, health professionals …
Cancer Immunotherapy Treatments, Shifra Sadowsky
Cancer Immunotherapy Treatments, Shifra Sadowsky
The Science Journal of the Lander College of Arts and Sciences
Cancer is the second leading cause of death in American, with over half a million deaths from cancer reported in 2009. Cancer chemotherapy treatments were developed in the nineteen hundreds and remain the backbone of current treatments; however, they have some limitations. New immunotherapy cancer treatments, where biologic agents are given to patients to influence the body’s natural immune response, are being researched. Among these immunotherapy treatments are co-inhibition blockade of T cells, and combination blockade treatments together with chemotherapy treatment. This review will discuss T cell activation and the role of T cell coinhibitors such as CTLA-4 and PD-1 …
Alopecia Areata: An Overview, Chaya Gestetner
Alopecia Areata: An Overview, Chaya Gestetner
The Science Journal of the Lander College of Arts and Sciences
This review seeks to find the most efficient treatment for alopecia areata. Alopecia is not very well understood as demonstrated by the unsatisfactory treatment options. The author reviewed many studies with different treatment options and concluded that treatment with Diphenylcyclopropenone (DPCP), a topical sensitizer, has the best results and that extensive research into the pathogenesis of alopecia areata is still necessary and may result in better treatment options for those afflicted with the disease.
The Pathogenesis And Treatment Of Gout, Daniel Silberstein
The Pathogenesis And Treatment Of Gout, Daniel Silberstein
The Science Journal of the Lander College of Arts and Sciences
In the past, the etiology of gout was simplistically believed to be based in the generous indulgence of rich foods and alcohol. However, research has revealed that gout has complex environmental and genetic origins. Specifically, researchers have begun to focus attention on the molecular basis of gout and its related features. These features include hyperuricemia, the stages of gout, and the decreased solubility of uric acid. Furthermore, with epidemiologic evidence indicating that the prevalence of gout is consistently rising, it is imperative that medical providers understand the research-based guidelines for treatment. This includes what medications to administer, monitoring for drug-induced …
Can Healthy Transplanted Tissue Be Used To Restore Motor Function In Patients With Parkinson's Disease?, Aliza Erlbaum
Can Healthy Transplanted Tissue Be Used To Restore Motor Function In Patients With Parkinson's Disease?, Aliza Erlbaum
The Science Journal of the Lander College of Arts and Sciences
Parkinson’s Disease is a condition that disrupts the lives the many people. The disease is characterized by a loss of dopamine producing neurons in the pars compacta of the substantia nigra of the ventral midbrain, and symptoms include a lack of motor control and rigidity in motion. Currently, there are many treatments available to treat patients with Parkinson’s disease. However, each treatment involves many adverse side effects that most wish to avoid. Science is discovering possible innovative, alternative options to treat Parkinson’s disease such as the transplantation of healthy dopaminergic neurons directly into the striatum of the patient. Methods include …