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Edith Cowan University

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2020

Toxicology

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Full-Text Articles in Medicine and Health Sciences

Co-Occurrence Across Time And Space Of Drug- And Cannabinoid- Exposure And Adverse Mental Health Outcomes In The National Survey Of Drug Use And Health Dataset 2: Combined Ecological Geotemporospatial And Causal Inference Analysis [Dataset], Albert Stuart Reece Jan 2020

Co-Occurrence Across Time And Space Of Drug- And Cannabinoid- Exposure And Adverse Mental Health Outcomes In The National Survey Of Drug Use And Health Dataset 2: Combined Ecological Geotemporospatial And Causal Inference Analysis [Dataset], Albert Stuart Reece

Research Datasets

Background: Whilst many studies have linked increased drug and cannabis exposure to adverse mental health (MH) outcomes their effects on whole populations and geotemporospatial relationships are not well understood.

Objectives: Determine: (1) if cannabis use is associated with major MH outcomes ascross space and time, (2) if such impacts are robust to multivariable adjustment and (3) if the relationship is causal.

Methods. Ecological cohort study of National Survey of Drug Use and Health (NSDUH) geographically-linked substate-shapefiles 2010-2012 and 2014-2016 supplemented by five-year US American Community Survey. Drugs: cigarettes, alcohol abuse, last-month cannabis use and last-year cocaine use. MH: any mental …


Contemporary Epidemiology Of Rising Atrial Septal Defect Trends Across Usa 1991-2016: A Combined Ecological Geotemporospatial And Causal Inferential Study [Dataset], Albert Stuart Reece Jan 2020

Contemporary Epidemiology Of Rising Atrial Septal Defect Trends Across Usa 1991-2016: A Combined Ecological Geotemporospatial And Causal Inferential Study [Dataset], Albert Stuart Reece

Research Datasets

Background: Cardiovascular anomalies are the largest group of congenital anomalies and the major cause of death in young children, with a range of data linking rising atrial septal defect incidence (ASDI) with prenatal cannabis exposure. Objectives / Hypotheses. Is cannabis associated with ASDI in USA? Is this relationship causal?

Methods: Geospatiotemporal cohort study, 1991-2016. Census populations of adults, babies, congenital anomalies, income and ethnicity. Drug exposure data on cigarettes, alcohol abuse, past month cannabis use, analgesia abuse and cocaine taken from National Survey of Drug Use and Health (78.9% response rate). Cannabinoid concentrations from Drug Enforcement Agency. Inverse probability weighted …