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Full-Text Articles in Medicine and Health Sciences
Cardiovascular Dynamics During Exercise Are Related To Blood Rheology, Michael Simmonds, Julien Tripette, Surendran Sabapathy, Sonya Marshall-Gradisnik, Philippe Connes
Cardiovascular Dynamics During Exercise Are Related To Blood Rheology, Michael Simmonds, Julien Tripette, Surendran Sabapathy, Sonya Marshall-Gradisnik, Philippe Connes
Sonya Marshall-Gradisnik
Background: The principal determinants of oxygen uptake (VO2) kinetics are controversial, with dynamic changes in central and peripheral factors mediating oxygen supply and utilisation suggested to be limiting. The aim of this study was to determine whether important parameters of blood rheology were related to the exercise-induced time-course changes in VO2 and cardiac output (Qc), or steady-state arteriovenous oxygen difference (a-vO2D) during submaximal cycling.Methods and Results: Blood was collected from ten healthy, recreationally active males and females (age: 21.7 ± 1.3 yr; bodymass index: 22.7 ± 2.0 kg..m-2), before each subject cycled at 105% of the first ventilatory threshold. Red …
Heart Rate Variability Is Related To Impaired Haemorheology In Older Women With Type 2 Diabetes, Michael Simmonds, Surendran Sabapathy, Gregory Gass, Sonya Marshall-Gradisnik, Luke Hassler, Rhys Christy, Clare Minahan
Heart Rate Variability Is Related To Impaired Haemorheology In Older Women With Type 2 Diabetes, Michael Simmonds, Surendran Sabapathy, Gregory Gass, Sonya Marshall-Gradisnik, Luke Hassler, Rhys Christy, Clare Minahan
Sonya Marshall-Gradisnik
Impaired heart rate variability (HRV)and haemorheology are independently associated with cardiovascular disease and diabetic complications. The aim of the present study was to investigate the relationships between parameters of HRV,and red blood cell (RBC) aggregation and deformability, in older women with type 2 diabetes. Twenty women (age 69 ± 2 yr) with uncomplicated type 2 diabetes and twenty controls (age 69 ± 3 yr) participated in the study. Beat-to-beat cardiac (RR) intervals over 5 min were analysed for HRV parameters in the time and frequency domains. Blood was sampled for RBC deformability, as well as RBC aggregation in two suspending …
Haemorheology Of The Eastern Grey Kangaroo And The Tasmanian Devil, Michael Simmonds, Oguz Baskurt, Herbert Meiselman, Michael Pyne, Michael Kakanis, Ekua Brenu, James Keane, Rhys Christy, Sonya Marshall-Gradisnik
Haemorheology Of The Eastern Grey Kangaroo And The Tasmanian Devil, Michael Simmonds, Oguz Baskurt, Herbert Meiselman, Michael Pyne, Michael Kakanis, Ekua Brenu, James Keane, Rhys Christy, Sonya Marshall-Gradisnik
Sonya Marshall-Gradisnik
The blood of two Australian marsupials, the eastern grey kangaroo (Macropus giganteus) and the Tasmanian devil (Sarcophilus harrisii), has been reported to have greater oxygen-carrying capacity (i.e. haemoglobin content) when compared with that of placental mammals. We investigated whether alterations of blood rheological properties are associated with the increased oxygen-carrying capacity of these marsupials. Eastern grey kangaroos (n = 6) and Tasmanian devils (n = 4) were anaesthetised for blood sampling; human blood (n = 6) was also sampled for comparison. Laboratory measurements included blood and plasma viscosity, red blood cell (RBC) deformability, RBC aggregation and the intrinsic tendency of …
A Comparison Of Capillary And Venous Blood Sampling Methods For The Use In Haemorheology Studies, Michael Simmonds, Oguz Baskurt, Herbert Meiselman, Sonya Marshall-Gradisnik
A Comparison Of Capillary And Venous Blood Sampling Methods For The Use In Haemorheology Studies, Michael Simmonds, Oguz Baskurt, Herbert Meiselman, Sonya Marshall-Gradisnik
Sonya Marshall-Gradisnik
There is accumulating evidence that exercise may improve disturbed haemorheological parameters that are typically observed in various chronic diseases, thus there is a growing interest in exploring the influence of various exercise models for the improvement of haemorheology. Blood sampling using venipuncture, however, can be limiting during exercise and/or in field settings. The purpose of the present study was to investigate whether venous and capillary blood samples yield comparable red blood cell (RBC) deformability and aggregation indices. Twelve healthy volunteers (6 males and 6 females; age 30±9 yrs; body mass index 24.9±2.8 kgm−2) provided blood samples that were collected simultaneously …