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Full-Text Articles in Medicine and Health Sciences

Expanding The Role Of Occupational Therapy For Oncology Patients: A Focus On Tumor- And Blood-Based Cancers, Erika N. Clark May 2022

Expanding The Role Of Occupational Therapy For Oncology Patients: A Focus On Tumor- And Blood-Based Cancers, Erika N. Clark

Occupational Therapy Capstone Presentations

Tumor and blood-based cancer diagnosis rates are increasing rapidly in the United States. To improve survivorship, treatment practices are constantly evolving, however, patients are often left to face the consequences of survival. With decreased range of motion, strength, and ability to participate in desired activities, patients may experience a decrease in overall quality of life. Through a holistic lens, occupational therapists are well suited to address the diverse needs of cancer patients through the duration of their cancer treatments. Unfortunately, occupational therapy remains a widely underutilized service for this population. This capstone experience worked to address this gap by expanding …


Combination Chemo-Pdt Ionic Nanomedicines As Enhanced Therapeutics For Cancer, Samantha Macchi Mar 2022

Combination Chemo-Pdt Ionic Nanomedicines As Enhanced Therapeutics For Cancer, Samantha Macchi

Arkansas Women in STEM Conference

Cancer remains as one of the leading causes of death in humans worldwide. Nanotechnology has made great strides in improving treatment for the disease. This work describes a simplistic approach to design self-assembled combination nanomedicines. A facile one-step ion exchange reaction is utilized to combine a chemotherapeutic (phosphonium) cation and photodynamic therapeutic (porphyrin) anion. An aqueous nanomedicine is prepared from the hydrophobic ionic combination drug via a single-step reprecipitation method. Upon conversion to ionic combination drug, improved photophysical properties of porphyrin were observed. These characteristics subsequently led to increased photodynamic therapeutic activity of nanomedicines—explained by greater singlet oxygen quantum yield. …


Detecting Multiple Myeloma In The Primary Care Setting, Anna Schweidler Jan 2022

Detecting Multiple Myeloma In The Primary Care Setting, Anna Schweidler

Capstone Showcase

Multiple myeloma (MM) is a hematological malignancy arising from differentiated B-lymphocyte white blood cells called plasma cells. Hematological malignancies are the fourth most diagnosed cancers, composing approximately 9% of all cancer diagnoses. Specifically, multiple myeloma attributes to approximately 2% of cancer diagnoses in the United States2. MM incidence has increased significantly over the past years, increasing 40% in the United States and 126% globally from 1990-2016 2. Affecting 7.0 out of every 100,000 people2, multiple myeloma is considered a rare form of blood cancer. Many strides have been made in the treatment of multiple myeloma …