Medicine and Health Sciences Commons^™

Intracranial Eeg Patient Analysis: Seizure Reduction In Refractory Epilepsy Following Depth Electrode Insertion, Shreyashish Roy-Chowdhury

Undergraduate Student Research Internships Conference

Rationale: The implantation effect describes an immediate reduction in seizure frequency following the insertion of intracranial electrodes. There is limited information regarding which patients will experience a reduction of seizures and the reason for the implantation effect. This study focuses on describing predictor factors for the reduction in seizure frequency in patients with medically resistant epilepsy implanted with depth electrodes.

Methods: We conducted a retrospective chart review of 89 patients who underwent intracranial electroencephalography (iEEG) monitoring with depth electrodes. Sixty-five of these patients had no subsequent therapeutic interventions and had a 3-6 month follow-up. Patients were grouped as either responders …

Return To Physical Activity Post-Total Knee Arthroplasty And Total Hip Arthroplasty, Bob T. Gao, Ashley Lowndes, Denise M. Connelly

Undergraduate Student Research Internships Conference

No abstract provided.

Screen-Viewing Among Young Children In Childcare: An Updated Systematic Review, Leann Blake

Undergraduate Student Research Internships Conference

Screen-viewing is one of the main forms of sedentary activity in which young children engage (De Decker et al., 2013). Despite health risks of sedentary behaviour in the early years being well documented (Statistics Canada, 2019), there remains a lack of research focusing on sedentary activities within the context of childcare settings in which children participate. The purpose of the current systematic review is to update and expand on Vanderloo’s (2014) systematic review and provide a synthesis of all relevant research on the levels of screen-viewing among young children (0-5 years) attending childcare (i.e., centre-and home-based childcare). In addition, this …

The Shadow Pandemic: A Systematic Review On The Effects Of The Covid-19 Pandemic On Children And Adolescents Obsessive-Compulsive Disorder., Nasong A. Luginaah

Undergraduate Student Research Internships Conference

No abstract provided.

A Review Of Accessibility And Return To Sport (Covid-19) Policy In Provincial And Territorial Sport Organizations Across Canada, Elias Boussoulas

Undergraduate Student Research Internships Conference

Issues with lack of accessibility in sport for those with both physical and mental disabilities have been prevalent throughout Canada. In order to understand and address these concerns, we must first review the provincial and territorial sport structure as well as accessibility policy in each provincial/territorial sport organization across Canada.

As a result of COVID-19, many provincial and territorial sport organizations found challenges in returning to play successfully while following provincial and territorial phased plans.The setbacks and restrictions put in place created a difficult environment for organizations to return to play, and without a sport-specific Return to Sport plan many …

Metabolomic Approach For Earlier Diagnosis Of Cisplatin-Induced Acute Kidney Injury, Steven Xiu, James (Yong Jin) Lim

Undergraduate Student Research Internships Conference

Cisplatin is a chemotherapeutic agent complicated by its dose-limiting nephrotoxicity. This commonly presents as acute kidney injury (AKI), which is characterized by a reversible decline in kidney function. AKI is currently diagnosed by increased serum creatinine (SCr) levels, but this rise in SCr is delayed limiting diagnosis to when significant renal damage has already occurred. Currently, there are no known biomarkers capable of predicting or diagnosing early-stage cisplatin-induced AKI. Metabolomics was used to identify novel predictive/early diagnostic biomarkers for cisplatin-induced AKI. We hypothesized that differences in metabolic profiles will be able to predict and/or diagnose cisplatin-induced AKI prior to rise …

Methodological Challenges In Pharmacoeconomic Submissions For Cancer Drug Reimbursement In Canada From 2019-2021, Nupur Krishnan

Undergraduate Student Research Internships Conference

Cancer is the leading cause of death in Canada, carrying a mortality rate of 1 in 4 Canadians. As new therapeutic options are developed, high drug costs place a huge burden on patients and the healthcare system. Due to budget limitations, not all pharmaceuticals can be publicly funded, so difficult decisions must be made for which drugs are funded and in what contexts. The pan-Canadian Oncology Drug Review (pCODR) evaluates submissions for new oncological pharmaceuticals to make reimbursement recommendations. Comprehensive analyses assessing limitations in recent oncology drug submissions have not yet been performed. The objective of this project, therefore, was …